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Bacopa tolerance

bacopa tolerance anxiety sleep aid

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10 replies to this topic

#1 ccnootropics

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Posted 21 May 2014 - 01:40 AM


I recently started taking bacopa as a sleep aid and to help with daytime anxiety.  I'm worried about tolerance developing over time or, worse, dependance.  Has anybody heard about or experienced long-term bacopa use as an anxiolytic?  Thanks!



#2 ILIkeBeer

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Posted 21 May 2014 - 02:21 AM

Does it work for anxiety for you?


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#3 ccnootropics

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Posted 21 May 2014 - 02:58 AM

Yes!!!  Sometimes a little too sedating, actually, which surprised me.



#4 ILIkeBeer

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Posted 21 May 2014 - 03:31 AM

Yes!!!  Sometimes a little too sedating, actually, which surprised me.

 

Sorry I have no experience using it... I bought some and have not used it yet I am trying lions mane out... can you tell me does bacopa work right away or does it take time to build up?



#5 ccnootropics

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Posted 21 May 2014 - 03:55 AM

For anxiety, yes - I felt the effects soon after taking the supplement (probably within 30 minutes).  



#6 AlmostEasy

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Posted 22 May 2014 - 09:53 AM

From studies I've read it actually takes a full 12 weeks for it to hit its saturation point and then the effects also remains for 4+ weeks after stopping administration of the herb.

 

I also read a few people's testimonies and there was talk of it causing anxiety, and that it stopped when they began taking the supplement at night instead of in the morning.

 

I'm not too sure if this drug does work in a way that would require tolerance monitoring but I do know for sure that it takes up to 3 months for its cognitive effects to fully kick in.  

 

If you do some searching around the forums you'll find the study I'm talking about, I'll try to remember to post the link here when I have more time.

 

Good luck!



#7 ccnootropics

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Posted 24 May 2014 - 06:19 PM

Thanks!  Yeah, I've done quite a bit of searching (although I don't think I'd found the specific study to which you were referring, so thanks for that :)).  I still haven't found much regarding tolerance though, so I thought I'd try my luck here lol.  Thanks again!



#8 gamesguru

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Posted 29 May 2014 - 05:09 PM

I noticed it peaked in effectiveness around the 6th week, then diminished. I suspect it activates the brain most during the 5-7th weeks.  I only use it 8-10 weeks in a row, then usually take 1-4 off. So tolerance, yes, unfortunately. Perhaps after the 6th week would be a good time to pull another ace out of your sleeve: ciltep, tulip, or other supplements.

 

I didn't notice any significant dependence or withdrawal, on the contrary, there seems to be a moderate lingering adaptogenic cumulative benefit, as AlmostEasy says, for 4+ weeks.



#9 Liquidfire

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Posted 30 May 2014 - 11:45 PM

Bacopa is one of my favorite Nootropics, and I try to keep it in all the time. It works wonders on my short term memory, aswell as sedating my stimulants(Ritalin, ALCAR, Oxi, Caf), together with L-theanine it's awesome.
It does make me feel like I am sedated like I am high, without the weed from time to time, but it evens out when I take a stimulant.


I have a question though, should it be taken in Fat solution, a water solution or with food?



#10 Gerrans

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Posted 31 May 2014 - 09:49 AM

I have a question though, should it be taken in Fat solution, a water solution or with food?

 

Bacopa is a water-based plant, so it is best not taken in water. To help it survive in water its nutrients need to be able to resist aqueous dissolution. Ethanolic extractions performed better in an antimicrobial study than aqueous solutions. (See Sampathkumar et al, 2008)
 

http://scialert.net/...jp.2008.230.232


Edited by Gerrans, 31 May 2014 - 09:51 AM.


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#11 gamesguru

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Posted 31 May 2014 - 05:33 PM

Probably best to take with food, assuming the axiolytics are lipophilic and the anxiogenics hydrophilic. Though, you could try taking it with water on an empty stomach as an experiment, who knows, it might work better that way.

 

Do you take bacopa with food? When I take it with fatty food it induces sleep and is very anxiolytic. When I take it on an empty stomach it tends to be stimulating. It seems that the sedative/relaxing bacopasides require a lipid transporter, and the more water-soluble ones seem to have stimulating and even anxiogenic properties.

I recommend eating something fatty like yogurt, bacon, olive oil, or coconut oil about 15 minutes before taking it for a more beneficial effect."

 







Also tagged with one or more of these keywords: bacopa, tolerance, anxiety, sleep aid

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