How much real world damage could they be in for if c60 in a blood transfusion was combined with chemotherapy drugs? I read an article that goes a bit beyond my understanding but I gather it increases the ability for the drug to kill cells (both good and tumour affected) Is that right? That study used c60 in water and in this abstract doesn't seem clear as to the route of c60 exposure eg oral, injected i.p i.v or s.c.
And then there is the 'second hand' method where one person takes something orally and then a part of the blood from that person then put in another person as a method of administration.
C60(Nd) nanoparticles enhance chemotherapeutic susceptibility of cancer cells by modulation of autophagy.
Abstract
Autophagy, an evolutionally conserved intracellular process degrading cytoplasmic proteins and organelles for recycling, has become one of the most remarkable strategies applied in cancer research. The fullerene C60 nanoparticle (nC60) has been shown to induce autophagy and sensitize chemotherapeutic killing of cancer cells, but the details still remain unknown. Here we show that a water-dispersed nanoparticle solution of derivatized fullerene C60, C60(Nd) nanoparticles (nC60(Nd)), has greater potential in inducing autophagy and sensitizing chemotherapeutic killing of both normal and drug-resistant cancer cells than nC60 does in an autophagy-dependent fashion. Additionally we further demonstrated that autophagy induced by nC60/C60(Nd) and Rapamycin had completely different roles in cancer chemotherapy. Our results, for the first time, revealed a novel and more potent derivative of the C60 nanoparticle in enhancing the cytotoxicity of chemotherapeutic agents and reducing drug resistance through autophagy modulation, which may ultimately lead to novel therapeutic strategies in cancer therapy.
http://www.ncbi.nlm....pubmed/21071824
The language doesn't seem to advise caution rather that it looks like a new and exciting way to deal with cancer. But would this mean that if someone was on chemotherapy drugs and supplemented on c60, they would require less chemotherapy to do the job and that their 'normal' dose when not on c60 is now an 'overdose' when on c60?
The guidelines on donation eligibility look pretty strict but also 'lax'. If I needed blood, I could end up with someone who has derivitives of a cocktail of medications for depression, blood pressure, hormones, aspirin etc. Maybe he/she is very unhealthy and has a diet loaded with transfats. The same person could be a chain smoker and had a bit to drink the night before (but not enough to look drunk at time of donation) and despite all this in the end, it would still save my life but if I could 'choose' I wouldn't choose from that particular donor.
Also if I was megadosing supplements like fish oil, maybe I shouldn't donate also because of blood thinning and the recipent could be someone on warfarin?
If I told the guys that I take Chlorella and Spirulina would they not want my blood also? Its an algae, 'maybe' not clean and 'could' have side effects in someone else.
So much of my diet is 'experimenting' with my own health. Yes I do want to see if c60 has a visual effect on the blood though, so I asked if anyone out there has added any to a vial of blood??
Edited by shifter, 23 July 2014 - 04:00 AM.