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TCA/Sedating AD with less antihistaminic (H1) effect?

tca antihistamic effect

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#1 Agomelatinehope

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Posted 10 September 2014 - 09:55 AM


Hi, My dr has tried to put me on several TCAs /Sedating ADs in low doses to sleep and I have read on the internet that they usually work quite well.

 

The problem is that I'm extremely sensitive to antihistamines (even a quarter of a pill of Doxylamine will completely make me zombie for 24h). 

 

I know each TCA has different actions on the different receptors and that some of them are more sedating or have more antihistaminic effect

 

Which one has the less antihistaminic effect?

 

Thank you







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