LONGECITY

 

Edited by crowdcell, 18 October 2014 - 11:41 PM.

what about increase or reverse this aging process in a smarter manner ? Supplementing in the raw component can have adverse effect. It seems like supplementing with co Q10 or hyaluronic acic.. Im really not a big fan

Thanks Tom, but have you read the book? This is a tiny piece of a comprehensive program. The question in no way addresses a possibility of any alternative, or what you might refer to 'smarter' manner of reversing aging. I am asking a very specific question related to the purity of PC. Kurzweil and Grossman must have based their advice on some research. I am trying to get hold of that particular piece of research. Maybe someone knows Ray or Terry well enough so they could ask them?

It looks like Ray and Terry sell standard 35% phosphatidylcholine. The label says 420 mg phosphatidylcholine and 10 calories, and 10 calories would make it ~1200 mg total weight.

Thanks for the link krillin! Even though the weight of components on the label is not straightforward for me, I found this list of literature at the webpage you gave the link to (see below).

 

References:

1. J Nutr. 1995. Jun;125(6): 1484-1489. S. Y. Chung et al.
2. Clin Neuropharmacol. 1993. Dec;16(6): 540-549.S. L. Ladd et al.\
3. Journal of Lipid Research. 2001. Oct(42): 1586-1593. M. N. Nanjee et al.
4. Circ Res. 2002. May 17;90(9): 974-980. G. Chiesa.
5. Circulation. 2001. Jun 26;103(25): 3047-3050. P. K. Shah et al.

If anyone is willing to help by going through these documents (this is what I found online for the references mentioned above):

1. J Nutr.: http://www.ncbi.nlm..../pubmed/7782901

2. Clin Neuropharmacol.: http://www.ncbi.nlm..../pubmed/9377589

3. Journal of Lipid Research: http://www.jlr.org/content/by/year

4. Circ Res.: http://circres.ahajo...t/90/9/974.long

5. Circulation: http://circ.ahajourn...tent/103/25.toc

 

These may or may not explain the reason why more pure PH is advised, however.

I will also write to info@rayandterry.com and if they give me an answer, I'll post it here myself.

 

Feel free to answer if you find the explanation first.

Maybe a bit offtopic, but NTFactor[1] came to my mind when reading this. I have always thought that NTFactor is some mumbo-jumbo and I have been reluctant to try it.

This is a good review of the so called "Lipid replacement therapy" [2]

 

[1] http://ntfactor.com/#&panel1-1

[2] http://www.nleducati...une-connection/

Thanks mitomutant. Ray Kurzweil and Terry Grossman actually give a list of chemical compounds that is quite similar to Lipid replacement therapy (LRT) you mentioned. Phosphatidylcholine (aka PC, or PtC) is just one component of the many suggested in the book, and one of several components that comprise the LRT therapy (in your links).

 

I am trying to use one source of supplement recommendations (the book TRANSCEND by Kurzweil and Grossman) at the moment to keep things simple. The simplicity also comes from the fact that the authors provide recommendations for one chemical compound at a time rather than giving a patented mixture (as is the case with LRT). Each chemical recommendation is supported by extensive research. However, sometimes the book contains somewhat ambiguous statements that lack specific references to proper research. That was the reason I started this topic. 

 

Edited by crowdcell, 29 October 2014 - 12:46 PM.

Thanks mitomutant. Ray Kurzweil and Terry Grossman actually give a list of chemical compounds that is quite similar to Lipid replacement therapy (LRT) you mentioned. 

Phosphatidylcholine (aka PC, or PtC) is just one component of the many suggested in the book, and one of several components that comprise the LRT therapy (in your links).

 

 

I am trying to use one source of supplement recommendations (the book TRANSCEND by Kurzweil and Grossman) at the moment to keep things simple. The simplicity also comes from the fact that the authors provide recommendations for each chemical compound at a time rather than giving you a patented mixture (as is the case with LRT). Each chemical recommendation is supported by extensive research, but, unfortunately, sometimes the book contains somewhat ambiguous statements that lack references to proper research, which is why I started this topic. 

Too bad I didn´t know about this book. Just bought the Kindle version.

 

Now that I think about it, protecting the mitochondrial membrane is actually a good line of defense for my condition. Maybe I have been too centered in reducing ROS and it´s time to explore this. Thanks.

I contacted customer support at the site of the book (info@rayandterry.com) a couple of times and finally got the answer. I asked them the initial question and also asked why the product they sell differs from what they recommend in the book. Here is their answer (shortened):

 

3) How did Ray and Terry come up with that 50% purity level? (Please point me to a specific research paper.)

"The reason R&T recommend such a high purity is because of the difficulty in absorbing PtC orally. There are no specific citations regarding this advice and specific number. ...

You could email Terry directly, perhaps he could offer you a more in depth answer regarding the percentage. Also he may be able to refer you to a physician offering IV PtC. ..."

 

 

Clean lecithin (i.e. no trimethylamine (TMA) contamination) does not result in TMA in the urine, while free choline does. That implies that the choline in phosphatidyl choline is completely absorbed before it can get to the gut bacteria that make TMA.
 

Thanks krillin! That page looks like it's about to disappear (with graphs missing). So I attached it to this letter. This is the quote from the paper to which (I think) you are referring:

 

Annoying.  My impression is hucksters Kurzweil/Grossman are once again just talking out of their bums.  They are conflating choline with PC.  PC is only 13% choline, so I think what they really mean is they want a relatively larger dose of choline than the pityful 195mg in a tablespoon of lecithin, which is only 23% PC, and to be able to sell such a product at premium like all their other overpriced, privately labeled supplements.

 

The solution to me seems to be just take choline bitartrate which is about 41% choline.  Nature's Way sells a mislabeled elephant-sized 1300mg tablet which provides 500mg of choline.  For $8 or so.

Edited by MachineGhostX, 19 January 2015 - 01:48 PM.

doesn't seem to difficult too get high concentration of PC : http://www.americanl.../aboutphos.html

Edited by logan113, 24 January 2015 - 10:42 AM.

Your body likes a negative ion environment to heal and grow. A cheap phosphorus rich supplement has an adverse effect on this environment forcing the body to dump precious alkalines like magnesium to maintain the status quo. Thats why its good to do green juicing but even plants have mineral deficiencies! I found PC could use all my available zinc stores in a couple of days, even on half dose!! PC from solgar and prienerspride (or something) are the ones I have tried and I must say the stuff is fantastic at rebuilding the whole body period. Im in my mid forties and can read the bottom line on the eye test chart and can hear them pesky anti loitering alarms on some days! It stops pulled muscles, stiff necks, rebuilds organs, it made my heart shrink as my left part of breast bone was raised beforehand(reasearch swollen hearts) I am currently fighting a blood fungus infection that will go away soon (I have been trying remedies for a year now lol but its under control, honest). It improves cognative functions but long term memory relies on your plasma fields so I recommend Magnesium (not oxide or citrated!!). Don't forget its the whole diet that gets results things will slow down if something is missing. I have a friend who added L-Proline to great effect, but just go easy with the aminos or you'll be mega dosing the vitamins before you know it lol.

It must be in oil form at least. The nano sized droplets can go through the tiny pores in a cell wall and also resist stomach actions when in an oil form.