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[vini]

So I've been flirting with nootropics for a while know, and I'd like to give it a shot.

I have previously been on sulbitiamine+vinpocetine under my neurologist's order, but I didn't even know what nootropics were then.

 

I've been doing some research, and most of the "traditional" nootropics (racetams, noopept, etc) aren't available in my country (brazil).

Also, the nootropics that are regularly used to treat dementia and other neurological disorders are usually heavily controlled (such as phenytoin, gabapentin, pregabalin, selegiline, etc.)

 

So I have limited choices.

I did some research on DDAVP (desmopressin) and found some good results on pubmed and the nootropic community, plus it is available Rx-free for me.

However, I'd like to know how good it really is, since most of the experiences I read seemed to glorify ddavp and portrayed it as a miracle drug.

So, anyone tried it before?

 

PS.: other nootropics that are easily found here, that seemed to be nice: DMAE, DL-phenylalanine and sulbutiamine.

[gamesguru]

Probably very similar in effect to vasopressin:

Delayed nootropic effects of arginine vasopressin after early postnatal chronic administration to albino rat pups.
Intranasal administration of arginine vasopressin (10 microg/kg) to albino rat pups had a strong nootropic effect during training with positive and negative reinforcement. This effect was different in animals of various age groups: training with positive reinforcement was improved in "adolescent" rats and pubertal animals, while during training with negative reinforcement, the nootropic effect of the peptide was more prolonged and persisted also in adult animals.

 

 

you could get a similar boost from ginkgo, ginseng, or green tea [there's much to be said about EC, EGCG, caffeine, theanine], eg:

Neuropharmacological Review of the Nootropic Herb Bacopa monnieri

In a meta-analysis, Neale et al.134 compared the nootropic effects of BM to Panax ginseng and modafinil (an eugeroic-wakefulness drug). Chronic BM produced the most consistent and largest effect sizes of the three. BM showed small- to medium-effect sizes for attention and information processing tasks. Larger-effect sizes were evident for auditory verbal learning tasks, sizes ranging from d=0.23 for delayed word pair memory to d=0.95 for delayed word recall (on the Auditory Verbal Learning Test) and d=1.01 for protection from proactive interference during delayed memory. These findings evidence the potency of BM, particularly in measures of verbal recall. Remarkably, contemporary findings appear to support the alleged use of BM in Vedic antiquity by scholars memorizing lengthy hymns.