2 replies to this topic

[Iamnobodi]

I recently started taking Brintelix my first AD 4 days ago. But for the past 2 years I have had troubles with low libido as a 22 yr old male which may have been caused by MDMA use. 

 

I am now reading that Wellbutrin can help with libido. Am seeing my psychiatrist on Thursday. 

 

So I was thinking of asking psychiatrist to switch to Wellbutrin as it helps with libido....what do you guys think?

[Mind_Paralysis]

Seems logical, but there's a few things to take into consideration - do you have anxiety as well? Bupropion (wellbutrin, voxra, etc ) is known to cause anxiety and agitation in some patients - more than other antidepressants, even.

 

I can vouch for this myself, as it pretty much turns me into a rage-monster the first two weeks or so of treatment.

 

So, do you have anger-management or anxiety -issues? Then I don't recommend it...

 

Well, unless you have ADHD of some kind as well? Then Bupropion is a really good starting-medication - it actually helps with some of the symptoms.

 

Otherwise, have you used cholinergic substances any? Bupropion is also a nicotinic acetylcholine receptor antagonist - meaning it helps with stopping smoking - however, if you are sensitive to anticholinergics, this will turn you into a complete dumb-ass... as anti-improved memory, especially verbal memory, is one of the less common side-effects.

 

I'm actually suffering from it myself at the moment! I can't remember what the opposite of improved is! And it's been more than two weeks, and the rage is gone, but I'm still a verbal dumb-ass.

[gamesguru]

yes, mdma is rumored to induce a condition not very distinguishable from pssd. lowering dietary tryptophan, expressing SERT, and promoting MAO are some strategies to reduce serotonin and hopefully restore a more pre-mdma like state. this should be done in "pulses", where you cycle antagonists for a few weeks to allow receptor resensitization, then you hit your body with bacopa and exercise [inducers of tph2] and flood the re-sensitized synapse with 5ht and bdnf... doing it like this will hopefully encourage maximal healing. another common idea is to put serotonin antagonists at brain.

• ginkgo has 5-HT1A antagonism [however mild 2a agonist]
• mitragynine, apocynum cannabinum, and tilia americana have 5-HT2A antagonism
• rikkunshito, amentoflavone, and kudzu have 5-HT2C antagonism