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supercentenarian study

hayflick limit telomeres supercentenarian longevity limit

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#1 Lazarus Long

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Posted 07 October 2016 - 07:11 PM


This hit the news yesterday and I'm curious what people think of both the study itself and the result indicated.  I suspect it supports Hayflick but that does not mean it is an insurmountable barrier to our goals.  I would also like to see the original study if anybody has it.

 

If it does support Hayflick then we need to reexamine how to extend and repair telomeres

 

What’s the Longest Humans Can Live? 115 Years, New Study Says

Carl Zimmer

MATTER

OCT. 5, 2016

 

On Aug. 4, 1997, Jeanne Calment passed away in a nursing home in France. The Reaper comes for us all, of course, but he was in no hurry for Mrs. Calment. She died at age 122, setting a record for human longevity.

Jan Vijg doubts we will see the likes of her again. True, people have been living to greater ages over the past few decades. But now, he says, we have reached the upper limit of human longevity.

 

“It seems highly likely we have reached our ceiling,” said Dr. Vijg, an expert on aging at the Albert Einstein College of Medicine. “From now on, this is it. Humans will never get older than 115.”


Edited by Lazarus Long, 07 October 2016 - 07:11 PM.


#2 Kinesis

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Posted 07 December 2017 - 12:05 AM

Some people said we’d never land on the moon, either.

Probably the Hayflick limit is at work, but telomere research is still on its infancy. It’s an obstacle to be overcome, not an inviolable law of physics.
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#3 Danail Bulgaria

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Posted 07 December 2017 - 10:34 AM

There are many, who lived over 115 :) At longecity some time ago very popular became Jeanne Calment. There have been people living to 116, 118, 115. The concept of the 115 years as a limit does not meet the criterias for the reality.


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#4 sensei

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Posted 12 February 2022 - 03:21 PM

In 2016, Kane Tanaka was 113. Mrs. Tanaka is now 119.

Dr. Vijg is incorrect. His theory has been falsified by real world observed data.

The Hayflick Limit, isn't really a limit after all.

#5 johnhemming

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Posted 12 February 2022 - 04:39 PM

In 2016, Kane Tanaka was 113. Mrs. Tanaka is now 119.

Dr. Vijg is incorrect. His theory has been falsified by real world observed data.

The Hayflick Limit, isn't really a limit after all.

 

It all depends upon the extension of telomeres.  The Hayflick limit almost certainly applies without the extension of telomeres, but there are ways of extending them (telomerase).  I think HIF can do this.

 

https://pubmed.ncbi....h.gov/15199161/



#6 sensei

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Posted 12 February 2022 - 07:00 PM

It all depends upon the extension of telomeres. The Hayflick limit almost certainly applies without the extension of telomeres, but there are ways of extending them (telomerase). I think HIF can do this.

https://pubmed.ncbi....h.gov/15199161/


If there is something (telomerase expression) that abrogates the Hayflick Limit (as telomerase does), and both somatic and stem cells can have lengthened telomeres due to telomerase,

IT ISN'T ACTUALLY A LIMIT
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