No replies to this topic

[chung_pao]

Hi

I just have a few quick questions.

I read this study: https://www.ncbi.nlm...pubmed/24799257

It states that Abietic acid and Pimaric acid are RAR agonists. Which is pretty unique. Downstream of that is activation of CAR and PPAR Gamma. (RAR Activation -> CAR, PPAR Gamma, Induction of CYP26.)

These substances only occur in Trees though. Such as Pine.

After travelling in China and Taiwan and trying a few things, which had quite potent effects, I also remembered that TCM occasionally uses Pine as medicine. Such as this one: https://tcmwiki.com/wiki/song-jie Called Song Jie, in Pinyin. (Yes, some of the terminology is weird "dispels damp-wind... not for patients with yin deficiency"... etc.)

I also found suppliers of Song Jie extracts and raw herb. https://www.chineseh...ong jie&x=0&y=0

So my questions are:

*Can abietic acid and pimaric acid be used as RAR agonists? (To induce cyp26, among other things.)

*Can Song jie (pine wood) extracts or decoctions be used as a source?

Or is this toxic/inefficient?

(This topic qualifies in the supplement section because: pine wold extract is a supplement, IMO. And pine bark extract is already being sold by Now foods and other known brands.)