119 replies to this topic

[ambivalent]

"It's one of the first 3, and some reason I doubt its the 3rd supplement for the eyes." 

 

Don't rule out lutein!

 

https://www.ncbi.nlm...les/PMC8223987/

 

"Three intervention studies using MRI indicated that 10 mg lutein intake over 12 months had a positive impact on healthy older adults’ brain activities during learning, resting-state connectivity, and gray matter volumes. Four cross-sectional studies using MRI suggested that lutein was positively associated with brain structure and neural efficiency during cognitive tasks. Conclusion: Although only nine studies that used similar datasets were reviewed, this systematic review indicates that lutein has beneficial effects on healthy older adults’ brain health."

 

Also may protect dopamine cells:

 

https://pubmed.ncbi....h.gov/25730317/

 

How much lutein are you taking?

[Mr Serendipity]

https://www.higherna...eyes/visualeyes

 

12mg Lutein.

 

I dropped the astaxanthin because the DHT blocking effect killed my libido.

 

 

 

[mbdrinker]

I suspect vit c is no longer sold to general public. I used 4 50mg tablets to make a drop of mb colorless. Now even 20 tablets don't make it colorless. Vit c is fake in Russia. I bet it's the same abroad. 

[pamojja]

I suspect vit c is no longer sold to general public. I used 4 50mg tablets to make a drop of mb colorless. Now even 20 tablets don't make it colorless. Vit c is fake in Russia. I bet it's the same abroad. 

 

In Europe (Germanspeaking) you get 100g Powder bottles in Supermarkets. This year raised its price from €1.95
(since I begun to use in 2009) €2.25. It still makes Lugols solution colorless. So still available here. I never used it in tablet form, since I took 25 g/d all these years.
 

[mbdrinker]

You are lucky. I now buy only citrus fruits for vitc on the food market. In this case i am at least sure to get some real vitc here.

[Mr Serendipity]

I swear there's nothing like higher doses of Vitamin C. I keep coming back to it.

 

I regularly take 1.5g daily. 1g as a pill, the other .5g come from my other supplements with formulas (like multivitamins, eye health etc..).

 

But it is NOT enough for me.

 

I've been taking higher doses the past few days (5g or more), because of a cold, and I've noticed.

 

1. My tongue after anything sugary doesn't feel yuck, and I don't eat much sugar.

2. My brain had a sense of calmness.

3. I was even laughing and some tiktok video yesterday thinking it was hilarious.

 

In fact that's the 3rd time I've confirmed point 1 now. And I went on my own strong course of anti fungal drugs for nearly 2 weeks, and it didn't make a difference. Only vitamin c does, it must have a good enough immune boosting effect to combat this issue.

 

As for the brain calmness, and happiness. Higher doses of vitamin c has done this before, especially with my OCD in the past. But I haven't observed the happiness effect when trying to recreate this again over the years, except when I initially done a vitamin c megadosing back in 2017, and experienced that high and energy levels on day 9 (check Post 20 of this thread). Note this was only 1/10 of that experience, but I've only tried higher doses of vitamin c these past 2-3 days, plus I'm currently ill/got a cold.

 

The major difference in my life recently, was getting my vitamin d levels up. I don't know what they were before, but I did some megadosing, then got tested , and they were 112nmol/L (range 50-120). In fact right now, I think I'm finding vitamin d a problem, with energy levels, sleep quality, and my posture, and yes I supplement with everything else, k2, magnesium, etc... What's funny is increasing vitamin d initially helped with energy levels and sleep. So I've stopped taking the 5k IU for now, and at a later date, may introduce 1k IU back in.

 

In fact I think vitamin d still helps with sleep, not the quality which has gone down with my energy levels recently (hence why I'll stop taking it for now). But the onset. Things like vitamin c megadose (5g), or zinc picolinate in the past would cause me major insomnia, and I couldn't fall asleep. I don't seem to get that much now I don't think going by recent experiences. In other words my onset of sleep has improved.

 

Basically to sum up all of this gibberish, I'm going to experiment with megadosing vitamin c again, and hope that having higher vitamin d levels will fix the insomnia I would get with it previously. Here's me hoping my brain can experience fun/happy/energy times like I did in post 20 again in 2017.

[Mr Serendipity]

I had a few initial emotional highs when upping my vitamin c, and then also brain calmness. However too much Vitamin C causes haemorrhoids/bleeding, I have no idea why. So I've settled on 5g max, technically 4.43g, as in 4 separate 1g vitamin tablets, and the 0.43 from formula supplements.

 

Too much Vitamin D causes acid reflux, fatigue, and worse neck posture, general posture, and feeling hunchbacked, but going down to 1k I.U. isn't enough for my wound healing and allergies issues. I've settled for 4k I.U. This still requires more testing, but so far today I feel alright.

 

 

All feelings to cough, completely wash away, they completely wash away, forever.

All feelings of dry throat, completely wash away, they completely wash away, forever.

All your allergies, completely wash away, they completely wash away, forever.

All thoughts, desires, cravings, and habits, for smoking, completely wash away, they completely wash away, forever.

 

 

I've also been testing my own self hypnosis files/suggestions, to see if I can:

 

• Get rid of the cough reflex.
• Get rid of the dry throat feelings which cause my cough.
• Get rid of my allergies.
• Stop smoking.

 

It's probably not the safest thing to do, especially the cough reflex one, as it might be covering up something more serious (I haven't been able to see an ENT through the NHS), or if I get something stuck in my throat, but I can still cough willingly, so far lol. But I swear it's having an effect on all 4 things, including my allergies. But it's not enough alone, I still need vitamin C and D to help. I've actually added "habits" to my smoking suggestion. Because even though I did lose my cravings for them, I would still buy and smoke them out of habit. Hopefully I've smoked my last one today.

 

I need all these to take effect, because my night time cough prevents me from wearing my apnea mouthpiece and getting good quality sleep. Time will tell, but I was able to wear it all night, despite smoking yesterday.

 

 

[pamojja]

The maximim allowable daily dose was established as 4g per day. I bet upping it will only strain the body to neutralize excessive amount.

 

I've been taking in average 25 g/d for 15 year. Though individual needs cane indeed be completely different, in my case it co-factored in remission otherwise considered non-reversible chronic disease symptoms, only.

 

Generally, high dose vitamin C intake simply isn't studied, therefore anyone can claim any bad effects or being 'neutralized, without any truth to it. However, this rare single study does point to possible healthy effects, only accomplished at many gram doses: http://www.longecity...156#entry797721

 

 

The oldest man from movie was 146 years old in 1949. Do you think supplements can replace clean water and natural food?

 

I think justified, some want to remedy the bad effects of bad life-style choices through supplementation. And some really dumb do think it could replace clean water, and other healthier life-style choices. On the other hand of the spectrum: it would be really dumb to not at all remedy some of the ill effects of bad life-style choices - which many are simply unable to let go of - with targeted supplementation.

 

But more rationale, supplementation is what it means. Supplementing a clean diet, not replacing it.

 

I know many very old people who smoked and drunk like mad their whole life, and got to a healthy age. Others with clean diet died young and ill. Both are certainly not the majority. But such exceptions do exist, too.

 

To claim it's fraud by some such exceptions - despite clean diet and high dose vitamin C - is silly.

Edited by pamojja, 14 May 2024 - 02:21 PM.

[Mr Serendipity]

Started up this experiment again. Been maybe about a week. Mind feels super clear today.

However I adding some other supplements the past couple of days, astaxathine 2mg with blackcurrant extract, and phosphatidylserine. And butyrate about a week ago. And I've been drinking 300g of blueberry smoothie in the morning the past few days, and drinking 1l of coconut water a day.

I've ordered some more supplements, namely astaxathine 12mg, and 1g black seed oil.

But today I do feel super clear, or at least less tiredness. And I actually drank 4 cans of 3.4% 440ml bud light last night for the first time in a long time.

So this experiment isn't isolated, but when I initially started a teaspoon of vitamin c last week, I was very sleep deprived, but fell more functional. Only today it feels like my sleep debt is way more suppressed, or I'm catching up, but still there.

I need to buy some Lutein and Zeaxanthin at some point and add to my stack. I'm all for trying everything to keep my brain outside of brain fog, or keep it antioxidant saturated.

Only issue with teaspoon of vitamin c is bowel tolerance, and very slight hemmorhoids. I'm going to take my vitamin c later in the afternoon, as I worried the bowel tolerance issue will prevent other supplements from my morning stack absorbing due to the faster gastric emptying.

 

Here's my current health plan:

Diet/Other: 

 

1 x 300g blueberry with 1 egg smoothie in the morning (egg helps give fat for other supplements)

1 x tsp of vitamin c in the afternoon (to prevent diarrhoea from effecting other supplements)

1L Coconut Water throughout the day

 

Health Shake:

 

500ml Lactose Free Milk

1 x Scoop of Whey Protein Isolate (no Sucralose)

1 x Scoop of Oats

1tbsp of Collagen Power

1 Banana

 

Morning:

 

Also need to buy: Lutein/Zeaxanthin

 

1 x Astaxanthin (2mg) with Blackcurrant fruit extract 4:1 50mg (using up won’t buy again, will be replaced with 12mg Astaxanthin supplement permanently, drop blackcurrant extract, can’t find a good replacement, use black seed oil instead)

1 x Butyrate

1 x Phosphatidylserine (try it again but take out if low it makes me tired/lowers cortisol too much) 

1 x Super K

1 x California Gold Nutrition, Astaxanthin, Astalif - 12mg (not yet arrived)

1 x NOW Foods, Black Cumin Seed Oil - 1g (not yet arrived)

1 x Vitabiotics Jointace

1 x Multivitamin

1 x Triple Magnesium Complex

1 x Ginger (300mg/5% gingerols)

1 x Vitamin E (200 IU)

1 x Rutin 

1 x Garlic Oil

1 x Gingko Biloba (increase acetylcholine and circulation, 1 doesn’t make me depressed like other choline supps)

1 x Vitamin D 1000 IU (pretty sure my hemmorhoids corrected from mega dosing vit d, not from rutin, so gonna add a smaller dose supp here, plus for immune system)(took out previously with boron due to hypercalcemia symptoms, but now added again without boron)

1 x Vitamin C (1g)

1 x Selenium (200mcg) (once a week)

1 x Starflower Oil (in freezer)

1 x EPA500

 

 

Before bed:

 

1 x ZMA

 

Edited by Mr Serendipity, 05 September 2025 - 12:18 PM.

[Mr Serendipity]

Okay I can say since my last post 5 hours ago.

That what I’m experiencing is a dopamine hit of sort, but with a clearer head.

I feel I’m teetering on hypersexuality, which is a welcome change of my low libido as of recent. But I also feel quite awake.

I could say my compulsive behaviours are more, but really they’ve been worse before, so maybe I’m just more aware of them with this clearer head.

I can’t really tell, other than this feels like a dopamine hit of sorts.

Caffeine from energy drinks can send me down this path, and I had one this morning. So it seems like the supplements and extra vitamin c is helping sustain and preserve that dopamine energy in the brain more, rather than crashing.

 

Hasn’t helped with procrastination though. I feel I’ve got the energy to do things,but I’m procrastinating, going for a walk on the treadmill for example. If I do it it will be at the last moment.

Edited by Mr Serendipity, 05 September 2025 - 05:18 PM.

[mbdrinker]

Definitely it's that interaction of those substances not vit c alone that gives you dophamine boost. I have read a book from 1964 about psychosis caused by medical aids. It enlightening about what happens when a substance gets into nervous system having penetrated the blood barrier. Actually, they could not find the cause of shizophrenia and could not even detect if it were serotonin or noradrenaline and adrenaline that caused psychodelic effects of psychomimetics and alike drugs. Also it turned out that metabolites but not substances themselves were causing those effects and it was not possible to monitor chemical transformations inside nervous system of a human as it required access to the brain of an individual but tests on animals always were not applicable to humans. For example apes die from small doses of substances not lethal for humans - thus all experiments on animals were useless. These problems have not been solved and won't be ever solved perhaps. What people actually want is euphory, so perhaps you'd better experiment with substances giving euphory than inventing stacks to achieve the same effect. Small dose of atropin alkaloid about 1.5mg gives euphory, larger dose like 10mg act as 500mg of mescalin. Atropin is super cheap, sold for people with asthma. And actually, man, it's not dophamine but its later metabolites which activate your psycho and besides 3 well known monoamines there are a lot of other receptors like histamine for example and other amines which influence your psycho. For example suprastin gives euphory, doxylamine makes your feel like you are 7years old. You need to experiment with mord substances. You can get muscarin and bufotenin from some mushrooms too. All those your stacks are child's play. Not serious at all.

[mbdrinker]

Substances inside nervous system are metabolizing into chains of other substances very fastly and it's not even possible to determine the entire transformation. For that reason they cannot find out causes of depression or shizophrenia and all those theories about lack of 3 monoamines as cause of depression are just fairy tales for consumers. In fact they induced atropin koma to cure astenic and depressive states. Thus those indian rituals with mescalin and psylocibin were actively employed in treatment in 50-60. I suspect that it breaks some structures and links which are part of selfconsciousness, thus acting as psychotherapy. Also hallucinations widen understaning of the world. That is one of the reason why psychomimetics are forbidden.

[pamojja]

Definitely it's that interaction of those substances not vit c alone that gives you dophamine boost.

 

In relation of ascorbic acid to schizophrenia, an excerpt of Linus Paulings book HOW TO LIVE LONGER AND FEEL BETTER, Chapter 10, Biochemical Individuality:

 

 

Ascorbic acid is present in the various body fluids and organs, especially the leukocytes and the blood. Its concentration in the brain is also high. When a person with an insufficient supply of ascorbic acid ingests a quantity of it, it moves very rapidly from the blood serum into the leukocytes, other cells, and organs such as the spleen. The amount remaining in the blood serum may be so small, less than the capacity of the mechanism of tubular reabsorption, that very little is eliminated in the urine.

A test was developed long ago (Harris and Ray, 1935) to show the avidity with which the tissues remove ascorbic acid from the blood serum. This test, called a loading test, involves giving the subject a certain amount of vitamin C by mouth or by injection, collecting the urine for the following six hours, and analyzing it for ascorbic acid. If an oral dose of about 1 g is given, most people whose blood serum is not depleted of the vitamin eliminate about 20 to 25 percent of it in the urine in six hours.

A person who eliminates a smaller fraction of the ingested ascorbic acid may do so either because he or she has been living on a diet containing an insufficient quantity of the vitamin, such that the tissues are depleted, or because some biochemical abnormality of his or her body operates to remove ascorbate from the blood serum very rapidly, perhaps by converting it rapidly into other substances. It was reported by VanderKamp in 1966 that patients with chronic schizophrenia required a loading dose of ascorbic acid about ten times greater than that required by other persons to cause the appearance of a certain amount in the urine. This observation was verified by Herjanic and Moss-Herjanic (1967).

The results of another loading test are shown in the illustration on page 114 (Pauling and others, Chapter 2 in Hawkins and Pauling, 1973). In this study forty-four patients recently hospitalized with acute schizophrenia and forty-four other subjects were given 1.76 grams of ascorbic acid by mouth, and the fraction excreted in the urine in six hours was measured. There was a twentyfold individual variation in this fraction, from 2 percent to 40 percent, with the schizophrenic patients excreting only about 60 percent as much as the others. This variation is probably partly nutritional and partly genetic in origin.

The distribution functions suggest that there are three kinds of human beings with respect to their handling of ascorbic acid, the low excretors, the medium excretors, and the high excretors. This idea has not, however, been thoroughly tested as yet.

Some of the subjects in this study were given 1.76 g of ascorbic acid every day for eight days, and the fraction excreted in the six hours after the last dose was determined. Of sixteen low excretors (less than 17 percent excreted), eight had moved out of the low-excretor class, whereas the excretion of the other eight remained low. This observation suggests that these persons have an abnormal way of handling their ingested vitamin C. They might require much larger intake to be in good health.

[mbdrinker]

Interesting info. I may add that based on info from that book from 1964 people with shizophrenia have such abnormal metabolism that they require quite different doses of many drugs and that doses lethal to healthy individuals can be well tolerated by shizopatients and vice versa. I have supposed that known 4 types of nervous system (sanguinic, melancholic,...) are also based on different metabolism and this leads to formation of some distinguished ~10 accentuations of character. The scientific philosophical aspect raised in that book was that scientists started major experimentaion with new drugs (which is beneficial to pharma industries) instead of searching the causes of diseases, researches, and study of interaction of existing aids and indeed author's intuitive thought about that threat has come true with that unholy trend starting already in 60s with more and more new drugs and less and less studies about existing drugs. The revolution in psycho drugs was happening in 1950-1953, the same years when 8000m high mountains were conquered and then it turned into more pharma business than search of the truth with more and more people taking ads and anxiolitics (including myself ). The life has become so unexciting that euphory nowadays has become more impotant than longevity. With age libido diminishes and agitation processes start to prevail in nervous system which requires intake of more depressing relaxing substances like alcohol, phenibut (gaba stuff), ads, etc. Vit c is potent in large doses (can even cure insomina) but within some days or weeks tolerance is developed which may suggest that large doses actually destroy normal metabolism in reaction to which body starts to produce some antidotes for vit c which results in vit c no longer acting. In other words I personally stick to that camp to consume normal quantities of vits from food and spending more money on psychodelic stuff and psychostimulators like ciltep stack and pervitin. As to longevity, I knew one guy going in for sports, eating only vegetarian food, obssessed about his health who ironically died from cancer after couple of anticovid injections. So it seems that longevity problem is more on agenda for those chosen to survive within the so called golden billion and for the rest - to enjoy the remaining time as much as possible.

[pamojja]

Vit c is potent in large doses (can even cure insomina) but within some days or weeks tolerance is developed which may suggest that large doses actually destroy normal metabolism in reaction to which body starts to produce some antidotes for vit c which results in vit c no longer acting. In other words I personally stick to that camp to consume normal quantities of vits from food and spending more money on psychodelic stuff and psychostimulators like ciltep stack and pervitin.

 

Sure, ascorbic acid isn't exactly a psychedelic.   

 

I however doubt it has been given a full trial, if one speaks of cognizable effects within days, gone within days or weeks.

 

I for example, started Linus Pauling's recommendations against CVD, due to a 60% walking disability from PAD. Only within months of increasing the ascorbic acid dose, and only when reaching the therapeutic window of 6 to 18 g/d, did the walking disability improve. As unintentional side effect a since 2 years persisting skin rush disappeared, and never came back.

 

During a 1 week water-fast without, the walking disability worsened quickly. Reminding me of Linus Pauling's advice, "Do not miss a single day."

 

However, really wanted long-term effects, were the remission of the walking disability after 7 years of use, in the context of life-style changes and comprehensive supplementation. Further, a remission of COPD symptoms after 4 years, and ME/CFS symptoms after 10 years of use. Of now 17 years on daily 24 g per day in average. More than 150 kg of ascorbic acid ingested in total.

 

So with long term high dose use, I can't confirm it would cease effectiveness at all. But might be even necessary against chronic conditions, due to biochemical individuality.

[mbdrinker]

No reason to be cynical about my post. Where did i insist on vit c to be psychodelic?... No complaints about its use for general health, from books it's really powerful also for regeneration in a way like anabolic steroids. I only complained about its quality in my country, namely degradation of it.

Btw, today i have experienced giant boost of phenibut action from vit c! I wrote yesterday about developing tolerance to phenibut after using it during a week with 1-2g per day but today i accidentally took 1g of vit C in addition to second daily dose of 1g at noon (first 1g dose was taken in the morning) and voila: the effect was that i almost fell asleep and this utter sleepiness lasted 4 hours. So, either i lacked vit c in the brain or it possesses the ability to upregulate gaba receptors. I am going to continue taking this mix to find out the truth. I started new topic yesterday about phenibut and gaba receptors if anyone is interested.

[pamojja]

No reason to be cynical about my post.

 

It wasn't meant with any bad intentions.

 

However, I'm frustrated why so few with very serious health difficulties actually don't seem to be able to give high dose ascorbic acid a serious trial, but still attest to its alleged ineffectiveness. Though I do understand that for most to take an acidic powder mixed in water many times daily, is just too much of a self-conquest.

 

Anything one can 'feel' from ascorbic acid, could only be minor short term effects. Any much larger damages to health would most likely have taken decades to develop, and would take as much to repair with repair molecules, like ascorbic acid.

 

Just think of all the decades of negligence in basic vitamin C metabolic functions, in someone above described as 'low excretors':

 

 

Vitamin C Basic Functions​

• Collagen synthesis. Vitamin C is an essential coenzyme in collagen synthesis. Cofactor in the hydroxylation of lysine and proline, stimulation of gene-expression in fibroblasts; development, maturation and repair of connective tissue such as skin, bone, tendons ligaments, scar tissue, blood vessels and cartilage (anti-scurvy effect = ascorbic). Lack of ascorbic acid results in poorly formed connective tissue in the skin, joints, muscles, and bones.
• Hormone production. Glucocorticoids synthesis in adrenal cortex (stress-response), and Vitamin D-hormone (calcitriol synthesis). Production of epinephrine and norepinephrine, (the hormones released by the adrenal gland in response to stress) are dependent on adequate vitamin C status.
• Neurotransmitter metabolism. Ascorbic acid is essential for the production of norepinephrine and serotonin, two important neurotransmitters in the brain. Conversion of tryptophan in 5-hydrotryptophan (=precursor of serotonin), hydroxylation of dopamine into noradrenalin, synthesis of L-dopa.
• Amidation of neuro-endocrinic hormones. Gastrin, CRH (corticotropin-releasing- hormone and TRH (tyreotropin-releasing-hormone).
• Bile acid synthesis and cholesterol breakdown and excretion. The first key step in the degradation of cholesterol (also tyrosine; bile-acid-synthesis, cholesterol-7-hydroxylasis, HMG-CoA-recductasis) depends on vitamin C. Cholesterol levels in the liver and blood increase if vitamin C status is impaired.
• Carnitine synthesis. Ascorbic acid - together with cofactors niacin, vitamin B6, lysine and methione - is essential for the formation of carnitine, an amino acid required for breakdown of fats for energy. Lack of ascorbic acid lowers levels of carnitine and reduces energy production, producing fatigue and muscle weakness.
• Tyrosine metabolism. Synthesis and catabolism.
• Iron absorbtion and metabolism. Vitamin C sharply increases non-heme iron absorption from diet or supplements. Raising iron transference from transferritin (transport protein) to ferritin (storage protein)-
• Folic acid activation. To tetrahydrofolate (THF).
• Antioxidant function. Vitamin C is the body’s primary water-soluble antioxidant. It is present in the blood, body fluids, and inside all cells and helps protect against oxidative damage by free radicals of lipids (lipid-peroxidation), proteins, nucleic acid and cell membranes. (anti-inflammatory and anti-degenerative effects, e.g. in cancers, diabetes, arthritis, cataracts and cardiovascular diseases..). Vitamin C is also important in the conversion (reduction) of iron and copper to the form in which they function as cofactors in many enzyme systems, such as reduced copper in superoxide dismutase (another antioxidant).
• Antioxidant regeneration. Central building-block in the redox-chain of vitamin C, vitamin E, coenzym Q10 and lipoic acid and/or glutathione, Regeneration of glutathion-disulfide into glutathione.
• Vitamin E sparing effect. Regeneration of tocopherol radicals (vitamin E radical) into the reduced, anti-oxidative active alpha-tocopherol (vitamin E).
• Protection of folate and vitamin E from oxidation. Ascorbic acid protects folate and vitamin E from oxidation and helps maintain these vitamins in their active forms.
• Endothelial cell protection. Raising of NO-bioavailability. (anti thrombotic and blood-lowering effect)
• Detoxification and excretion of drugs and chemicals. Ascorbic acid helps maintain the enzyme systems in the liver that detoxify and excrete drugs and toxic environmental chemicals (such as pesticides and heavy metals). Detoxification of xenobiotika (synthesis/anti-oxidative protection of CYP 450) in the liver, excretion of toxins.
• Antiviral and antibacterial effect. Vitamin C is important for healthy immune function. It is essential for optimum activity of white blood cells and production of the chemical mediators that direct the immune response. Lack of vitamin C sharply increases vulnerability to infection (Immunocompetence). Stimulation of the cellular (antibodies) and hormonal immune system (interferon), protection of phagocytic membranes from oxidative self-destruction (prolonged function-time of immune cells), activation of complementary systems and of chemotaxis.
• Anti-glycation. Inhibition of protein glycosylation and AGE-formation. (e.g. HbA1C).
• Anti-allergic. Vitamin C plays a role in controlling body and blood histamine levels (histamine degradation and mast cell stabilization), and blood histamine levels increase when vitamin C status is poor. High levels of histamine can aggravate allergies, asthma, stomach ulcers, and certain psychiatric disorders.
• Anti-carcinogenic. Inhibition of the formation of carcinogenic nitrosamines from nitrites and secondary amins (especially of the digestive system), protection of DNA from oxidative damage.

 

 

I only complained about its quality in my country, namely degradation of it.

 

Almost all ascorbic acid is produced cheaply in China. For which reason any other substance should be added to dilute it, at such a cheap price? In fact, the cheapest vitamin available. I used ascorbic acid from a decade ago, without significant degradation. And I didn't feel a thing, except experiencing most unlikely remissions after years of use.

 

Edited by pamojja, 11 September 2025 - 02:51 PM.

[mbdrinker]

And after 15 years of 17g of vitC per day is your liver healthy? The maximum recommended daily dose was stated to be 4g for usual average person. I think if it helps you, no problem, then take it. But i hezitate about health benefits of megadoses in the long term for myself. Where in nature is it possible to get such megadoses from usual food even if you eat only vitc rich vegetarian food? I bet that body will start resisting it as against hypervitaminosis. I currently need any psychodelic stuff to break connection with the reality as much as possible. MB was my savier but currently it's all fake in russia.

[pamojja]

And after 15 years of 17g of vitC per day is your liver healthy?

 

I had amoebic hepatitis around 2000. Probably damaged by 7 malarias and the pharmacological treatment then, too. When I started to supplement 17 years ago, I had an enlarged liver, 2 non-circulated nodules on the right edge of the liver (5 + 8mm), NAFLD. With in average 24 g per day of ascorbic acid, all reversed.

 

A cystitis circumscripta of the bladder, one tubercle (6mm) in the left lung, gone too. As an added plus, since supplementing comprehensively I don't get sunburns anymore (without protection).
 

[longevitydiary]

I had amoebic hepatitis around 2000. Probably damaged by 7 malarias and the pharmacological treatment then, too. When I started to supplement 17 years ago, I had an enlarged liver, 2 non-circulated nodules on the right edge of the liver (5 + 8mm), NAFLD. With in average 24 g per day of ascorbic acid, all reversed.

 

A cystitis circumscripta of the bladder, one tubercle (6mm) in the left lung, gone too. As an added plus, since supplementing comprehensively I don't get sunburns anymore (without protection).
 

The liver has a very rapid rate of cell renewal. Just like fatty liver, if alcohol consumption or obesity is controlled, it will naturally resolve. Some small nodules are not tumors but rather focal fat deposition, small lesions caused by inflammatory reactions, or even imaging artifacts. As the underlying causes are managed and the liver repairs itself, these nodules may no longer be visible on imaging. As for the nodules in the left lung, those of inflammatory origin can naturally disappear.

[pamojja]

The liver has a very rapid rate of cell renewal. Just like fatty liver, if alcohol consumption or obesity is controlled, it will naturally resolve.

 

Didn't for more than 10 years after the last Malaria. After commencing supplementation and lifestyle changes only. Always had a BMI of 20 and drank no alcohol. But quitting added sugar, processed foods, and changing to omnivore, might have been important factors.

 

However, liver enzymes ALT, AST and GGT, averaging at 35, are still not in the optimal range below 30.

Edited by pamojja, 14 September 2025 - 09:34 AM.

[mbdrinker]

Malarija in Austria? Where did you catch it?

As you can see no one takes such crazy vitc doses except you but i agree that everyone has different body. I knew a girl pro balltet dance with her dad being famous doctor and shd told me that it's harmful to take more than 100mg of vitc per day. Propoganda of meagdoses came from one crazy american guy whose wife was megadosing and died from cancer. So your theory is kind of debatable. But i don't insist on it to be false.

Edited by mbdrinker, 14 September 2025 - 09:02 PM.

[pamojja]

Uganda, Malawi trice, India trice.

 

As you can see no one takes such crazy vitc doses except you

 

Information about Orthomolecular medicine must be really scarce in Russia. It's available to MDs here in Austria as a additional specialty, but not by insurance, only out of one's own pocket.

 

Many of those Orthomolecular docs of the past have been documented on doctoryourself.com.  For example, Klenner, treading Polio: http://www.doctoryou...klennerbio.html

 

Or Cathcart: http://www.doctoryou.../titration.html
 

 

Over the past ten-year period I have treated over 9,000 patients with large doses of vitamin C (Cathcart 1, 2, 3, 4, 5).

 

And many more. So I'm one only after many before me. Thousands. Ever heard of the Gulo gene defect?

 

 

 

 

 

 

[pamojja]

Propoganda of meagdoses came from one crazy american guy whose wife was megadosing and died from cancer. So your theory is kind of debatable.

 

You speak of Linus Pauling? He is one of 5 people to have won more than one Nobel Prize.

 

He died at age 93 of prostate cancer. That is 16 more years lived than todays 77 years life-expectancy in the US. Or even 24 more years than in Russia.
 

 

 

 

 

 

 

 

 

[mbdrinker]

Yes, I guess it was Paulig. His wife was also megadosing and died from cancer earlier than average life expectancy. But i don't deny the tempting idea that restoring prehistoric metabolism may cause a quantum leap to biblical Mafusail's longlivity.

However, from stidies of longevity in Ussr: Shirali Muslimov lived 168, one another person 180, one slav guy 145, Poddubny's grandfather 120, my grandgrandgrandfather 104 - all without vitc supplements.

[mbdrinker]

I don't have any nootropic effect from large doses. If I take 2g per day it cures insomnia. Never had any nootropic effect from vitC. It also gave some energy boost in 00s either because i was younger or because it had other quality. I will try to take 4g per day as i have enormous levels of histamin but i have acute heart pain from suprastin and as per his info above it lowers down histamin. I need to try something to cure awful diseases.

[mbdrinker]

Experiment on prehistoric metabolism activation continues. So, yesterday after 2.5g of vitc during daytime i fell asleep during watching video which had happened previously probably in childhood. First thoughts: pma launches production of depressing substances like serotonin, melatonin, etc (ads like amitriptilin also cause sleepiness during couple of weeks); pma potentially makes you less responsive to genetically modified foods and malicious substances such as secretely modified drugs, alcohol, tea, pseudocoffeee, etc. My organism is very succeptible to midified crap and as i have mentioned i suffer from unbearable skin itching a little less than 10 years already. I suspect it's malicious infection by hostile individs using my genecode for production of those parasites, it's kind of margellons' mystical disease. So pma potentially may alleviate suffering if it manages to transform my body into something prehistoric so that parasites won't be able to be so active as the entire changing metabolism produces another environment. The test will continue.

[mbdrinker]

The concept about deficiency of certain vitamincs for specific individuals is really powerful and extremely overlooked by medicine. The idea is that external supplementation of those needed vitamins restores the homeostasys of organism with resulting production of all needed substances turning a man into superman. I suspect that this is the reason why testosterone supplements do this magical turn , i.e. hormones is another besides vitamins substance needed for proper functioning of the body. But does the matrix need supermans? Definitely, not. That's why steroids are prohibited in my country.

[Mind]

Please keep the topic focused upon Vitamin C and Nootropic effect.

[mbdrinker]

So far i have noticed more relaxing and antiinsomnia effect than any nootropic but i am not megadosing (2-3 g per day). I also have more prolonged sleep with vivid dreams and also strange dreams. My sleep has become more sound. I suspect it has increased melatonin production 100x times. It works some nice way. Megadosing would be kind of expensive for me. Besides, i am scary about my liver as i do feel kind of its swelling even from 2g daily dose. But i confirm abovestated claims that it's really powerful in its influence on organism and perhaps a good choice by the cost/efficiency ratio vs many drugs of the past which have become fake or low quality like russian phenibut, melatonin, and almost all psycho-influential drugs here. That's why i have created a specific topic where i study interaction of simple drugs to catch psychodelic effect.