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L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

tyrosine l-tyrosine limitless nootropic motivation drive concentration sociability intelligent speech working memory

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#1 Sovr'gnChancellor£

  • Location:London

Posted 23 February 2012 - 12:10 AM


Too Long to Read? Basically, I've been taking Tyrosine for a few days and gradually increased the dose in the last couple of days to 7 500mg capsules. I feel as if I've experienced a small part of what the Limitless character experienced but without any side effects (well always working may be one!) or nationwide fame.

I feel more intelligent, speak more intelligent, act more intelligent and perform more intelligently. This is not just my own opinion, classmates have expressed surprise and said that 'I'm on the ball these days'. Working memory is phenomenal and my frontal lobe has felt alive with activity (shown through extensive working memory, alertness, extended concentration and focus and extended awake).

Does anybody else experience this? If not, does it only work for some people, or does it mean that I was actually lightly low in dopamine levels? What on earth is going on here because I'm currently drawing up plans for world domination (Joke - I'm actually drawing up plans for university domination in terms of running for SU President next year and putting out my name on campuses through many journal articles, socialising and club memberships. - This is particularly a great change in my character as I was mildly complacent and withdrawn beforehand.)

What is going on here?

(P.S. Was NZT's theorised workings really just extended dopamine release and production?

P.P.S. What is even better is that I've experienced continued and heightened benefits when off the Tyrosine today - possibly extended and continued dopamine production and release?)


In the film Limitless, an below-average guy begins taking pills (NZT-48) and suddenly becomes intelligent, motivated, successful and grandly ambitious. The book ('the Dark Fields') also follows the same pattern but differs somewhat in plots. (Personally, I prefer the film due to the whole film experience plus the ending where he is successful, affluent, proud and grand and running for senate.)

Anyway, I watched this film many months ago last year. I (unsuccessfully) tried to see what would aid me in attempting to become something similar to that (!) I invested in Citicoline, ALCAR and then later herbals and a number of racetams. The racetams were better in my attempt but did not exactly put me on a road at least close to what Eddie Spinola in 'The Dark Fields' was like (where the drive to get things done was nagging and strong). It did however make concentration better.

(Also, be aware that I was not researched much in dopamine and its effects and was really quite oblivious to it, only having a passive regard to it.)

Now, to this thread:

For the past week, I have been dabbling on and off with Tyrosine in the morning on an empty stomach. What began as a couple of 500mg capsules ended up increasing to nearly four times that.

Then, a couple of days ago (20 Feb), I took 7! And the day quickly turned haywire. When I was out at lectures, my speech was excited, fast and sociable. The motivation and drive to interact was astronomical.

But I was racy, couldn't sit still and was actually thinking grand thoughts. At this time (the middle of the day), I was like '7 caps may be good for socialising and whatnot, but maybe not good for focussed and uninterrupted academic work.

Little did I know that I was completely wrong.

After lectures, I came back to dorms and was still quite racy and excited from my stimulated social interaction with people (lol just talking to them!). Then, I calmed myself down as I was consciously aware that I had important projects to complete.

Now, at first I thought (now in the late afternoon) that the effects were wearing off. They weren't. It seemed that I was still stimulated, but it was controlled stimulation and focus was scarily on point.

In a few hours, on that single day, I completed two pieces of work (to put things into perspective: it takes me about a week to complete one piece of work, the other piece of work was the second half of a project which should have taken me one to two weeks - but everything seemed to click into place and research time was considerably decreased as it was more focussed with no distractions).

The next day (21 Feb), I completed another piece of work - and these pieces of work weren't scantily done. They were copiously referenced and were long in length. The day before I was quite shocked at how much and how good I'd done. The next day, I wasn't very shocked because I just wanted to get things down - thoughts of shock and surprise seemed distracting and arbitrary - I just had to get things done.

After I'd completed that piece of work, I grew again restless and wanted to get things done - but I'd done everything. So, I started to completely improve the format and layout of my CV (Resumé) and look into future career options. I then started to draw up plans to write a couple of articles and essays for the yearly journal at uni. This is quite shocking - as I've never had much time for these grand adventures beyond academia and into the land of extra-academic intellectualism. But I was so motivated, so grandiose.

It didn't stop there however; on that next day (21 Feb), I planned to sleep on time to make some important sessions in the morning.

I was on my bed at 10pm, planning to leisurely read for a couple of hours in order to fall asleep by midnight. It didn't work out. I stopped reading about five minutes to midnight and tried to sleep. I was on the bed for a half hour still wide awake and stimulated. I then grew restless and rationalised that if I was just wasting time on my bed trying to sleep when I couldn't, I might as well get things done. So, at about 1am in the morning, I started to do some extra work and research to talk about in class. I didn't get to sleep until around 3am with prior reading of textbooks, note-taking and researching.

I then woke up today at 8am having had five hours sleep. Normally, I'd be really very tired and shattered, but I was already stimulated and quickly woke myself up by a swift burst of reading activity.

A couple of people also mentioned today about how I was on the ball and expressed surprise at my work and contribution - that's shockingly weird as I'm clearly normally thought of as unremarkable.

What is interesting is, today, I didn't take any Tyrosine, but the effects are STILL there, even right now. It was another hyper-productive day and my concentration and focus on long streams of text and assimilation of memory is worrying (as in, worryingly amazing). I am no longer even distracted by my desire to relax with my usual relaxing activities like surfing on nets and posting on student forums and listening to music - they seem to give less pleasure than usual and work can thus be carried out for much, much longer and with more directed focus and intellectual interest.

Is Tyrosine really this amazing? Of course, I can infer that all of this is the result of more dopamine flowing around - is this true? It's just quite shocking the amount I've gotten done in the past few days and how well they've been done. And there haven't even been any noticeable crashes in the day (only light fatigue at night, but nothing that can't be remedied with some fruit and conscious effort).

In short; (and this is the great bombshell - at least to me), it's like coffee/caffeine but completely without the jitters, anxiety, crash and mental strain - it seems to have a whole day's worth of working power.

Lastly, working memory is phenomenal and my speech is articulate and intelligent (both style and substance).

Edited by Sovr'gnChancellor£, 23 February 2012 - 12:12 AM.

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#2 Delafuente Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Florida, USA

Posted 23 February 2012 - 02:31 AM

Is Tyrosine the only supplement you are taking? It's great that you are experiencing these things you mention, but it is always best to wait a while before casting judgement in regards to supplements/drugs.

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#3 stephen_b Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

Posted 23 February 2012 - 02:58 AM

It's a dopamine precursor that can cause alertness. Like a lot of these precursors you can build a tolerance to them.

I've been reading lately about how tyrosine is needed to make thyroid hormones, so it ain't necessarily all about dopamine.

#4 niner Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Philadelphia

Posted 23 February 2012 - 03:22 AM

Sovr'gn, from your description, it sounds like the Tyrosine induced a hypomanic state. Various substances will do that to me, and I wish I was that way all the time.

#5 Sovr'gnChancellor£ Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:London

Posted 23 February 2012 - 03:49 PM

Is Tyrosine the only supplement you are taking? It's great that you are experiencing these things you mention, but it is always best to wait a while before casting judgement in regards to supplements/drugs.


Yes, in these past few days - the only other things have been a B Complex and Zinc. Before the Tyrosine, I was dabbling with the Racetams and Citicoline, but no of these had similar effects to Tyrosine. They were more mediocre.

It's a dopamine precursor that can cause alertness. Like a lot of these precursors you can build a tolerance to them.

I've been reading lately about how tyrosine is needed to make thyroid hormones, so it ain't necessarily all about dopamine.


Yes, I thought as much about the dopamine. However, I have been off it since yesterday and today, so as to not build a tolerance. The effects were still there yesterday, but have somewhat dissipated today. Having said that, I've just got in an order of Mucuna Pruriens 350mg and I've just taken two - I felt a mild increase in wakefulness, but nothing to the extent of Tyrosine, which is weird - however, I have heard and read that the first few days of Mucuna Pruriens may be quiet and unremarkable before it kicks in.

About the thyroid hormones - I thought that just had to do with metabolism and whatnot. I'm not very versed in this - but do the thyroid hormones have any effect on mood, alertness and cognitive effects?

Sovr'gn, from your description, it sounds like the Tyrosine induced a hypomanic state. Various substances will do that to me, and I wish I was that way all the time.


Yes, I thought so - but hypomania doesn't seem to be such a bad thing. I mean, on Wikipedia, it states:

Individuals in a hypomanic state have a decreased need for sleep, are extremely outgoing and competitive, and have a great deal of energy. However, unlike with full mania, those with hypomanic symptoms are often fully functioning.


Specifically, hypomania is distinguished from mania by the absence of psychotic symptoms and grandiosity, and by its lesser degree of impact on functioning. Hypomania is a feature of bipolar II disorder and cyclothymia, but can also occur in schizoaffective disorder. Hypomania is also a feature of bipolar I disorder as it arises in sequential procession as the mood disorder fluctuates between normal mood and mania. Some individuals with bipolar I disorder have hypomanic as well as manic episodes. Hypomania can also occur when moods progress downwards from a manic mood state to a normal mood. Hypomania is sometimes credited with increasing creativity and productive energy. A significant number of people with creative talents have reportedly experienced hypomania or other symptoms of bipolar disorder and attribute their success to it. Classic symptoms of hypomania include mild euphoria, a flood of ideas, endless energy, and a desire and drive for success. A lesser form of hypomania is called hyperthymia.



I mean, hypomania and even mania don't seem to be 'disorders' as such. I can't even fathom why some of the 'symptoms' are even called 'symptoms' in the first place - lots of people have really high ups throughout their lives when not on anything.


The only drawback I could think of concerning tyrosine and hypomania was reduced sleep - but this can be countered by taking it early in the morning and not taking it everyday. On the other hand, it also seems to improve my actually sleeping itself - but that could be the B Complex.

#6 MrHappy Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Australia

Posted 23 February 2012 - 08:52 PM

Mmmm.. I don't think you're going to enjoy homeostasis..

When you reach that stage, I do know something that may 'reset' your receptor balance. :)



#7 niner Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Philadelphia

Posted 23 February 2012 - 09:11 PM

I mean, hypomania and even mania don't seem to be 'disorders' as such. I can't even fathom why some of the 'symptoms' are even called 'symptoms' in the first place - lots of people have really high ups throughout their lives when not on anything.


Well, mania can get pretty crazy, but I had a hypomanic episode from prednisone, of all things, and damn, there wasn't a single thing wrong with it. If I could be that way all the time, I'd sign up in a heartbeat. I have a suspicion that there are some people whose natural state approaches what would be a hypomania for most of us.

#8 Sovr'gnChancellor£ Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:London

Posted 24 February 2012 - 03:42 AM

Mmmm.. I don't think you're going to enjoy homeostasis..

When you reach that stage, I do know something that may 'reset' your receptor balance. :)


What do you mean? :D :p Are you talking about tolerance?


I mean, hypomania and even mania don't seem to be 'disorders' as such. I can't even fathom why some of the 'symptoms' are even called 'symptoms' in the first place - lots of people have really high ups throughout their lives when not on anything.


Well, mania can get pretty crazy, but I had a hypomanic episode from prednisone, of all things, and damn, there wasn't a single thing wrong with it. If I could be that way all the time, I'd sign up in a heartbeat. I have a suspicion that there are some people whose natural state approaches what would be a hypomania for most of us.


Those kind of people also tend to be intellectual geniuses/really ambitious and successful people etc

Also, I do believe that I was mildly hypomanic between (late 2009 - summer 2011) when I was attempting to immerse myself in lots of intellectual activity - funnily enough, I was taking nothing back then apart from a simple multivitamin.

I believe my dabbling with nootropics now is my attempt to recreate that foregone era - I do believe that sexual abstinence and spinach :D :lol: had something to do with it as there was a lot of that in that period (especially eating entire bags of spinach in mid 2011 when doing exams)....

Anyway, I'm beginning to sound silly - it's nearly 4am over here and I attribute my not sleeping to taking Mucuna Pruriens today and fussing about my life's future....

#9 Elus Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Interdimensional Space

Posted 24 February 2012 - 05:12 PM

I wonder if this kid is manic (has mania?) http://www.popsci.co...o-played-fusion

#10 MrHappy Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Australia

Posted 24 February 2012 - 10:42 PM

What do you mean? :D :p Are you talking about tolerance?.


Exactly that.. you start losing 5-HT receptors and things become normal again... and if you stop taking vast amount of a dopamine agonist, you crash.

Fortunately there are supplements that act as dopamine modulators.

#11 Sovr'gnChancellor£ Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:London

Posted 25 February 2012 - 05:46 PM


What do you mean? :D :p Are you talking about tolerance?.


Exactly that.. you start losing 5-HT receptors and things become normal again... and if you stop taking vast amount of a dopamine agonist, you crash.

Fortunately there are supplements that act as dopamine modulators.


Ah, I see.

Also, I wouldn't say up to 4g of Tyrosine is a 'vast amount'. Studies I've seen show much more than that with recommendations of no more than 12g a day; hence why I haven't 'crashed', most especially because I don't take it everyday.

And what are these dopamine modulator supplements?

#12 Ampa-omega Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:united states

Posted 25 February 2012 - 09:39 PM

im interested in long term results of this Hows it going so far Original Poster?

#13 Googoltarian Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:EU

Posted 25 February 2012 - 09:56 PM

I'm probably not only one who ordered tyrosine after reading this topic :laugh:

I really want to read study that shows tolerance buildup to amino acids... MrHappy?

#14 MrHappy Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Australia

Posted 25 February 2012 - 10:27 PM

It's not an 'insane' dose, by any means, but it's about 4x the common dose, so it will mean more dopamine and noepiniphrine production.

Dopamine modulator: uridine
http://www.longecity...ne-uridine-dha/

It has a lot of other helpful aspects, such as rapidly rebalancing neurotransmitters/receptors, increasing synaptogenesis and much more.

I think it'll help the other end of the equation, but I possibly wouldn't jump into it until you've fully given L-tyrosine a chance. See how you feel over a longer period. If you start feeling depressed prior to dosing L-tyrosine, or if you have to increase the dosage, keep it in the back of your mind as a possible washout cycle or even a replacement/addition.





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#15 MrHappy Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Australia

Posted 25 February 2012 - 10:42 PM

It's not so much a tolerance to amino acids. It's tolerance to the increased neurotransmitter, DA.

Autoreceptors will say 'nothing to do here' and disappear.

This also happens to pretty much to all receptors when there is an abundance of resources and is a widely observed effect. This is why tolerance is discussed regularly.

For L-tyrosine, DA production is regulated by tyrosine hydroxylase by around 75%. L-tyrosine should be able to boost dopamine levels by 30% in a normal healthy brain. If this is sustained, tolerance will develop.

On the other hand, if OP has a problem, such as phenylketonuria, which would stop him from synthesizing his own tyrosine, he may be starting with the opposite of tolerance - an abundance of dopamine receptors, owing to a lack of sustained dopamine.

This would probably manifest as mania during early stages of tyrosine supplementation. Long term supplementation will still form a tolerance, but the mania should disappear and he'll just feel healthy normal/good.

Edited by MrHappy, 25 February 2012 - 10:45 PM.

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#16 Elus Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Interdimensional Space

Posted 25 February 2012 - 11:09 PM

It's not so much a tolerance to amino acids. It's tolerance to the increased neurotransmitter, DA.

Autoreceptors will say 'nothing to do here' and disappear.

This also happens to pretty much to all receptors when there is an abundance of resources and is a widely observed effect. This is why tolerance is discussed regularly.

For L-tyrosine, DA production is regulated by tyrosine hydroxylase by around 75%. L-tyrosine should be able to boost dopamine levels by 30% in a normal healthy brain. If this is sustained, tolerance will develop.

On the other hand, if OP has a problem, such as phenylketonuria, which would stop him from synthesizing his own tyrosine, he may be starting with the opposite of tolerance - an abundance of dopamine receptors, owing to a lack of sustained dopamine.

This would probably manifest as mania during early stages of tyrosine supplementation. Long term supplementation will still form a tolerance, but the mania should disappear and he'll just feel healthy normal/good.


Hey, great explanations, thanks. Given what you've said above I can only conclude the following: You cannot permanently induce mania. Is this right?

In theory, what would happen if you managed to sustain (Articially or biochemically, or with some imaginary technology) the number of DA receptors while increasing DA production at the same time? Is such a thing even possible?

#17 MrHappy Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Australia

Posted 26 February 2012 - 04:18 AM

Sorry, I'm not aware of anything, yet, that would prevent this built-in function.

'Cycling' the supplement, or instead, consistently increasing the doses (which generally leads to complications), are the usual methods.

What I was commenting earlier, is that uridine would be a way to more rapidly rebalance the 5-HT autoreceptors during the 'off-cycle' or 'low-dose cycle', reducing the down phase, if mania is the desired state.

If you are shooting for a happy 'normal', it's much easier and can be achieved with no 'up' or 'down' cycle.



#18 Elus Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Interdimensional Space

Posted 27 February 2012 - 12:39 AM

Sorry, I'm not aware of anything, yet, that would prevent this built-in function.

'Cycling' the supplement, or instead, consistently increasing the doses (which generally leads to complications), are the usual methods.

What I was commenting earlier, is that uridine would be a way to more rapidly rebalance the 5-HT autoreceptors during the 'off-cycle' or 'low-dose cycle', reducing the down phase, if mania is the desired state.

If you are shooting for a happy 'normal', it's much easier and can be achieved with no 'up' or 'down' cycle.

Do you have any guesses as to what would happen if you maintain DA receptors while increasing dopamine? Just in theory.

Edited by Elus, 27 February 2012 - 12:39 AM.


#19 MrHappy Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Australia

Posted 27 February 2012 - 05:21 AM

Faster path to 'normal', with a side of tolerance, perhaps - depends on the doses. :)



#20 Geijutsu Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Qatar

Posted 02 March 2012 - 05:33 PM

So any recent news about your progress so far, sovr'gn?

#21 Ampa-omega Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:united states

Posted 05 March 2012 - 09:46 PM

bump for updates..

#22 protoject Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Canada

Posted 08 March 2012 - 04:04 AM

It's a dopamine precursor that can cause alertness. Like a lot of these precursors you can build a tolerance to them.

I've been reading lately about how tyrosine is needed to make thyroid hormones, so it ain't necessarily all about dopamine.



Agreed. I believe the increase in energy is definitely related to thyroid more than dopamine, personally. Perhaps that's because I notice similar effects from small doses of iodine, which I assume is improving the transport of thyroid hormones in my body.

Also I thought I would say that Tyrosine seemed to work a lot better than me for N-Acetyl-Tyrosine which really just seemed to be overkill. Damn, actually, I want to take tyrosine again. Has good potential as a natural mood booster and stimulant [if you ever use anything to go on an outdoor exploration with, this is it]. It was very interesting mixed with tryptophan... like yin and yang almost

#23 lne Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Brazil

Posted 08 March 2012 - 11:42 AM

Ive tried L-Thyrosine and i can tell you that it is my gold for now... Ive used it only twice and the effect was amazing, i felt exaclty the same as you described.

As ive read that we can develop tolerance of it, so i decided to only take when necessary. For example, i would take it if i have a presentation or an important meeting.

Have you noticed any tolerance ? How long are you taking it ?

#24 Geijutsu Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Qatar

Posted 26 March 2012 - 11:45 AM

OP seems to have disappeared completely :mellow:

#25 Josh Kwon Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

Posted 26 March 2012 - 05:36 PM

Maybe's hes off to bigger and better things.

#26 Divien Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Estonia

Posted 26 March 2012 - 05:48 PM

1st day of L-Tyrosine (about 5g) with Lecithin + vitamin B complex + vitamin E and vitamin C and I feel no different (still no motivation or energy, no side effects). I also take about 5000 IU vitamin D every day and just finished a bottle of Zinc amino acid chelate. Will see what the following days bring.

#27 Divien Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Estonia

Posted 28 March 2012 - 07:31 AM

3rd day update, still nothing. But that may very well just be me since I can't even feel the effects of methylphenidate. Only things I know that have an effect I can recognize myself are alcohol and cannabis, I don't consume either often nor in large amounts. L-tyrosine only seemed to have an effect the first time I ever tried it (a couple of months ago) and that could have been a placebo, it was like a small buzz went on my head and I felt a little energetic but it was short-lived.

I will not give up though, since I will need to find out what's wrong for my future's sake and of course FOR SCIENCE! :)

#28 Pirate Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:aus

Posted 10 November 2012 - 11:05 AM

I had a great day on tyrosine a couple of weeks ago when I'd only had 5 hours a sleep (which is not very much for me, I can't function properly with less then 8. Even 7 and a half is bad for me).

I haven't been able to get the same kick from it since, but also haven't been as sleep deprived.

Does anyone know if Tyrosine is reknowned for working well with Sleep Dep? What else could Tyrosine be co-dependent on to produce good and importantly regular and reliable results?

#29 FDA Approved Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:UK

Posted 10 November 2012 - 06:59 PM

Also ordered after reading this thread, I am often sleep deprived so I hope it can at least prove valueable then.

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#30 tommix Re: L-Tyrosine - 1/8 of 'Limitless' scenario achieved.

  • Location:Lithuania

Posted 17 November 2012 - 09:44 PM

it makes me wonder why people does things just to do.... what you will do with that dopamine? do you're studding some super hard science at university so you need to increase dopamine so you can remember things more? Do you have some trouble in movement? maybe parkinson's ?
The guy who created this topic by reading his post you see that he's going crazy :D Also this feelings is VERY easy to make via placebo. Placebo is VERY strong thing if you think that some stuff will make some effect - you will gonna see that effect. Sometimes you make it via stimulating brains into doing this, so not always stuff really works, it may be just your brains ability to do stuff for you if you really want to.

Anyways the only good stuff about dopamine i see is for making easier to remeber things. also playing with dopamine receptors is really BAD idea!
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