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Let's build a complete map of the human body's known metabolic pathways

krebbs yang cycle receptor map graph theory

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9 replies to this topic

#1 BLimitless

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Posted 30 January 2013 - 04:41 PM


Does such a thing exist?


If that does, then what about a complete database of all receptors and their ligands.

I am envisioning a huge web of drugs and targets. I was drawing one a long time ago but my knowledge of pharmacology is far too limited and specialised in only certain things to go very far.

#2 Mind

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Posted 30 January 2013 - 06:38 PM

Here is something similar that we are trying to accomplish. Please take a look.

#3 BLimitless

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Posted 01 February 2013 - 02:42 AM

Thank you very much. I would love to volunteer with you guys, I see someone already stated the idea in depth, perfectly described. Just floating around waiting for university to start, I need a good kick up the butt in the form of some kind of mindblowing project to help humanity.

Anyway...

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#4 Mind

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Posted 01 February 2013 - 09:07 PM

Well, Dr. Furber made a very in depth graphic of metabolism and aging a few years ago. Some people have critiqued it. Many people have looked at it. I am not sure that it has advanced the science or understanding of aging all that much. Many of these info-graphics are just not as accessible, interactive, or intuitive as they need to be. That is why we are trying the new effort to bring a lot of this data together in a more engaging platform. Please consider helping out.

#5 BLimitless

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Posted 02 February 2013 - 03:38 AM

I believe we must represent this data along four dimensions. Representing it along two will cause it to look unintuitive and chaotic.


Ironically the perfect representation of this concept is a live human body.

#6 niner

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Posted 02 February 2013 - 03:53 AM

I'd say that the perfect representation is closer to a cell than a whole organism, but in truth there are a lot of levels here. You guys might want to poke around at NCBI and see some of the tools they've put together that link genes, receptors, compounds and the like.

#7 SONOFDARTH

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Posted 18 November 2014 - 10:47 AM

Did this ever go anywhere?  Great idea!  I was re-reading Guyton's Phys the other night and thought about something like this.  What's the status?



#8 Mind

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Posted 18 November 2014 - 07:22 PM

Nothing being generated here at LongeCity. Not sure about some of the other efforts similar to this in other areas of the world.



#9 Multivitz

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Posted 25 January 2015 - 12:47 PM

I thought about this for over 25 years and have come to the conclusion that because the body is self regulating it only suffers when a component is missing or levels of other components effect balance in other systems. Its a simple hypothesis that holds true, because its the environment (including beliefs) effects the genetic material, the cell wall controls cell activity that is repondent to a magnitude of influences. Example: Organic D3 effects two thirds of the human DNA. I find rda and bottle doses a guide, symptoms have to be read to decide on dosing. Of course drugs are not needed, all they provide is a strain on the livers resources, chemicals memory confusion for the cell membranes and DNA damage in some cases. Most drug residues feeds fungus, most ills are fungus driven! To make it more apparent put it like this, everything effects everything else because everything (food components and their use) is linked one way or another, there are some exceptions, but they need to be looked at when symptoms appear. Obviously theres relationships to how stuff is used which is where science can help make insights and shortcuts into dietry regimes. Sometime the body makes stuff out of nothing that resembles a known pathway!!!
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#10 Jose_LER

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Posted 10 April 2015 - 08:38 AM

I think the only small problem would be that the information that anyone can extract would be too complex to understand.

It would be useful? Yes

It would be understandable by people? I don't think so very the human body is very complex.

 

I think the most useful way would be to build an artificial intelligence engine that can understand all the information. A human brain cannot understand that huge amount of information. It would be too complex to analyze and understand by a person.

But your idea is really good!







Also tagged with one or more of these keywords: krebbs, yang, cycle, receptor map, graph theory

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