Rapamycin makes lab animals live longer, yet at humans it is immunosupressing. This is an approach to modifying the rapamycin molecule to be immunoneutral or immunobeneficial while keeping or amplifying the longevitry effects.
sulfurized chlororapamycin
methoxycaffeine is a sedative as it passivates the receptors that caffeine would have stimulated, so methoxylating or even ethoxylating that part of the rapamycin molecule that causes immunosupression creates a drug that is immunoneutral,or possibly slightly beneficial. Viewing the molecule though it has some =O, I think swapping those with =S will make the former rapamycin
halogenation creates greater receptor affinity, many mainstream pharmaceuticals like triamcinalone (700 times greater receptor activity from halogenation compared with cortisone) or even chloral hydrate (about 20 or 40 times more sedating than Ethyl alcohol from halogenation) Thus halogenate the areas of the rapamycin molecule that cause longevity
immunobeneficial longevizing rapamycin based molecule with methoxylation.jpg 73.44KB
3 downloadsThe halogenation of the particular part of rapamycin that causes mTOR longevity while methoxylating the immunomodulating part of rappamycin to either be immunoneutral or immunubeneficial creates a new longevity drug. At the image I suggest swapping the =O with =S where rapamycin gloms to a protein to be immunoactive, this should create immunoneutral or immunobeneficial effects. Then I suggest general nonspecific halogenation to create a bunch of halogenated varieties. The halogenated version that most longevizes yeast is then an immunoneutral or immunobeneficial longevity chemical to make humans as well as other mammals live longer
