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[mtn2011]

http://www.naturewor...way-reverse.htm


May 03, 2013 11:47 PM EDT
Say Bye-Bye to Gray Hair, Researchers Find Way to Reverse The Process

By Isabel Alface

Gray Hair


What has become ubiquitous with age - gray hair - may soon become a thing of the past. Forget about trips to the hair salon, or buying box dye to cover up those roots, a team of European researchers say.

In a new research report published online in The FASEB Journal people who go gray develop massive oxidative stress via accumulation of hydrogen peroxide in the hair follicle, which causes hair to bleach itself from the inside out.

The report notes that the enormous accumulation of hydrogen peroxide can be cured with a proprietary treatment developed by the researchers described as a topical, ultraviolet B-activated -- sunlight -- compound PC-KUS, a modified pseudocatalase.

What's more, the study also showed the same treatment works for the skin condition, vitiligo which is a condition that causes de-pigmentation of sections of skin. Although vitiligo isn't an agonizing, or dangerous condition, it can still be pretty distressing because it can change people's appearance so much, according to the American Academy of Dermatology. One to 2 million people in the U.S. have vitiligo, according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases.

"For generations, numerous remedies have been concocted to hide gray hair," said Dr. Gerald Weissmann, the editor-in-chief of The FASEB Journal, "but now, for the first time, an actual treatment that gets to the root of the problem has been developed. While this is exciting news, what's even more exciting is that this also works for vitiligo. This condition, while technically cosmetic, can have serious socio-emotional effects of people. Developing an effective treatment for this condition has the potential to radically improve many people's lives."

In the current study, an international group of 2,411 patients with vitiligo, 2.4 percent were diagnosed with strictly segmental vitiligo and after treatment of the pseudocatalase activated via sunlight, the pigment of the skin and eyelashes returned.

The researchers did not specify when the treatment would become available for retail.

Edited by mtn2011, 05 May 2013 - 04:55 PM.

[reason]

The graying of hair with increasing age is an early sign of increased oxidative stress in skin tissues around hair follicles. Researchers here demonstrate that it can be locally reversed by an antioxidant-based strategy. This shouldn't be taken to indicate that antioxidants are of general utility: the researchers here are carefully replacing the role of a specific natural antioxidant in an intricate chemical process, not just picking any random antioxidant and throwing it into the mix.

People who are going gray develop massive oxidative stress via accumulation of hydrogen peroxide in the hair follicle, which causes our hair to bleach itself from the inside out. The build up of hydrogen peroxide was caused by a reduction of an enzyme that breaks up hydrogen peroxide into water and oxygen (catalase). Hair follicles could not repair the damage caused by the hydrogen peroxide because of low levels of enzymes that normally serve this function (MSR A and B). Further complicating matters, the high levels of hydrogen peroxide and low levels of MSR A and B, disrupt the formation of an enzyme (tyrosinase) that leads to the production of melanin in hair follicles. Melanin is the pigment responsible for hair color, skin color, and eye color.

The report shows that this massive accumulation of hydrogen peroxide can be remedied with a proprietary treatment developed by the researchers described as a topical, UVB-activated compound called PC-KUS (a modified pseudocatalase). What's more, the study also shows that the same treatment works for the skin condition, vitiligo.

Link: http://www.eurekaler...s-gha050313.php

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