I've been playing around with nasal administration lately. Nasal administration makes it easier for water-soluble substances to bypass the blood-brain-barrier and reach high concentrations into the brain.
TurboSnort is a caffeine nasal spray. The product does not work, unfortunately - because the dosage is very low. It is a homeopathic spray, I didn't know that when I bought it. Also, the liquid contains something very minty and it feels bad in the nose.
I have opened the TurboSnort spray by unscrewing it (it's very easy), threw away the remaining content, washed it very carefully and then I have put GNC B Liquid Complex, then sprayed 4 times, 2 in each nostril.
Surprisingly, this didn't hurt. Perhaps because the GNC Liquid B Complex is NOT minty like most nasal sprays.
The result was a short lived rush on the skin of my head and a bit of increased awareness. Not very spectacular, but it's clear that this route of administration works.
After 30 minutes or so I have tried to spray again. This time, the nostrils hurt like hell.
It is clear to me that spraying B complex damages the nasal mucous. Perhaps with a different composition of B complex this could be done safer (the liquid I used has a light red color and a sweet taste).
Other possible dangers of administering substances by insufflation:
- depending on the composition of the liquid, you could feed local bacteria or fungi and get or aggravate a sinusitis
- the liquid itself could contain some harmful bacteria, or grow some if it doesn't contain preservative
- damage to the nasal mucous and septum
Other things that could be interesting:
- make a true caffeine spray, capable of delivering 25 mg of caffeine (from my research on the web I think it's enough)
- B12 methylcobalamin spray
- modafinil
I could perhaps use a true caffeine spray as a "turbo boost" button once per month (in order not to risk damage to the nose mucosa).