I first discovered Phenibut probably 6 months ago now, and my experience was similar to that of many others. As someone who has suffered from anxiety in the past, and even intermittently to this day it naturally seemed like this potent anxiolytic compound with apparently zero negative side effects seemed amazing. However I have gradually come to realise that Phenibut has some deceptively creeping downsides that become more and more apparent with continued use.
I have never experienced acute withdrawal from Phenibut as I have always been quite careful, the most I have ever used in a row was 4 days (this was a rarity), and never over 2.5g in a day, usually between 1 and 1.5g.
Since the start of the year, my use has probably averaged about twice a week, up 3 times from February-ish, usually between 1 and 1.5 g a day again.
While this usage does not seem particularly excessive to me, I have come to realise that Phenibut surely must be the cause of some creeping negative effects on my outlook, mood and overall motivation.
Amongst some concrete things I can put my finger on, I have struggled to get up early for most of the year (I was an early riser last year, and felt much better and more productive for it). I have struggled to motivate myself to continue the various sports and fitness type activities that I was pretty dedicated to last year. On the contrary, I have found it a real struggle to motivate myself to leave the house on some days, and the thought of going to a gym and interacting with people has given rise to irritation and avoidance type thought patterns. I have become less interested in social activities, preferring to just work on my various projects alone.
This has been a very gradual thing, and I feel the onset was somewhat masked by a period in December where I was very busy with work and simply didn't have time to do much else. I have been aware however that I have not felt quite myself since the start of the year, but attributed it to some sort of emotional hangover from a relatively high-stress month or so. I have recently concluded that it is almost definitely Phenibut that is to blame, although I was somewhat blind-sided by this because as mentioned I have not experienced any acute withdrawal symptoms.
I have now not used it for about a week and at the moment I don't plan to use it again. During this week I have also allowed myself to basically take some time off from my usual pastimes to reassess things, instead of going through a weird period of irritated anxiety during the buildup to having to do something and then a mix of relief and guilt when I make an excuse not to do it. Over the last few days I have been fairly liberal with use of some other more familiar noots of dubious effectiveness (Piracetam, Aniracetam) and known stimulants (Caffeine, Phenylpiracetam) to blast through the last dregs of this weird creeping and antisocial malaise. I feel pretty good about this realisation and decision.
If you'll excuse this bloggish type introduction, I actually do have a few questions I would like to start some discussion about.
- What exactly is going on that causes the long subjective duration of Phenibut's effects? Wikipedia states that it's half-life is only 5.3 hours, yet there seems unequivocally to be something going on beyond that.
- From a neurological standpoint, what is going on with this creeping apathy? I have considered that this might not be unique to Phenibut, and is possibly something that could be experienced with other GABA agonists like alcohol, except in that case, there would be a physical accompaniment to the mental feelings.
- What is going on, neurochemically, in the brains of people who use this drug daily, sometimes for years, in huge doses? Floating around reddit and other places there is at least one report of someone using up to 10g/day for 5 years... their self-reported experience is that it has enriched their life, and if this is the case it is hard to argue against their decision. However, is this sustainable, or is it inadvisable for any reason other than the fact that if they for some reason can't get access to their daily dose they may be in some danger?
I don't personally like the idea of being entirely dependant on any chemical, but I do accept that for some people self-medication like this may seem the only option for a normal life. That said, it was reports like this that made me think my own use could surely not be any issue at all, when I was starting to suspect the origin of my feelings of malaise but was still somewhat in denial about it.