2 replies to this topic

[Danail Bulgaria]

I want to read more about the damage accumulation theory of aging.

 

Can you recommend me some reading?

[Avatar of Horus]

You may have read some of them, but they may be good for starting:

Here is an older topic of mine about with an overview study of the various theories:

An overview on the aging theories and potential interventions to extend life
http://www.longecity...to-extend-life/

 

Then there is the fightaging blog summaries:

The Root Causes of Aging

• Aging is Caused by Damage
• Accumulating Cross-Links
• Buildup of Amyloid Between Cells
• The Failing Adaptive Immune System
• The Failing Innate Immune System
• Declining Lysosomal Function
• Mitochondrial DNA Damage
• Nuclear DNA Damage
• Buildup of Senescent Cells

and those of the SENS homepage:

Aging as We've Known It - http://sens.org/rese...s-weve-known-it

and the Introduction to SENS research

http://sens.org/rese...o-sens-research

 

And maybe the Wikipedia with the links:

Ageing - http://en.wikipedia.org/wiki/Ageing

Senescence - http://en.wikipedia....wiki/Senescence

 

Also a Pubmed search may give you some relevant material to read.

 

Edited by Avatar of Horus, 29 April 2015 - 06:41 PM.

[Kalliste]

Read Ending Aging by Aubrey yet? It's very interesting and goes into great detail. Helped me understand some things that had slipped me by in the anti-aging blogosphere.

 

  Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime Paperback – October 14, 2008

http://www.amazon.co.../dp/0312367074/