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Novel PDE4Ds : Selective Negative Allosteric Modulators

Started by bossmanglb , Jun 09 2016 09:33 PM
pde monkeys camp long term potentiation learning memory

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#1 bossmanglb

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Posted 09 June 2016 - 09:33 PM


This paper outlines novel PDE4D selective allosteric modulators and tests them in monkeys--which generally, you'd think a much better model than the murine alternative

 

http://journals.plos...al.pone.0102449

 

These novel compounds seem to demonstrate a robust cognitive enhancement effect. And at precisely the intersection of interest and need for healthy, high-functioning neurotypicals. 

 

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Also tagged with one or more of these keywords: pde, monkeys, camp, long term potentiation, learning, memory

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