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Chris Linnell's Longevity Review Newsletter



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March 2021 Longevity Review

Posted by Chris Pollyanna , 11 April 2021 - - - - - - · 1,521 views
supplements, nmn, resveratrol and 6 more...
Hello and welcome again to this month’s longevity review. There was plenty of good news this month with a new compound showing efficacy in humans and the first inklings as to the best time of day to take your supplements, but also a disappointing result with regards to Nicotinamide Riboside. However, even disappointing results increase our understanding s...



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February 2021 Longevity Review

Posted by Chris Pollyanna , 28 March 2021 - - - - - - · 1,842 views
supplements, nmn, fisetin and 3 more...
Hello and welcome again to this month’s (delayed) longevity review. It turns out that slicing off a chunk of your right index finger is not a good idea. Who knew? Finally been able to touch type & use a pen again the past week.
Keeping the intro brief so that I can get this out before the end of the month, suffice to say that perhaps what will be...



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January 2021 Longevity Review

Posted by Chris Pollyanna , 22 February 2021 - - - - - - · 1,783 views
supplements, progeria and 7 more...
Now that 2020 is firmly in the rearview mirror and the light at the end of the COVID tunnel is becoming brighter, longevity science becomes less of a distraction and more of an enticement towards better times. Examples of this include hope for progeria sufferers using gene therapy, a new method to discover drug combinations and yet more pre-clinical evide...



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2020 Longevity Year in Review

Posted by Chris Pollyanna , 10 January 2021 - - - - - - · 2,028 views
supplements, lifestyle and 7 more...
Despite the year we’ve had, it is always a pleasure to take a step back and look at how far the longevity field has come, for we have come a long way in understanding and being able to treat ageing. 2020 was no exception. From breakthroughs in cellular reprogramming to human trials in blood plasma fractions, the longevity field continues to accelerate....



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December 2020 Longevity Review

Posted by Chris Pollyanna , 02 January 2021 - - - - - - · 1,841 views
supplements and 7 more...
Hello and welcome to 2020’s final longevity review. As this dreadful year mercifully comes to a close, it has at least left us with a last few parting longevity gifts. In particular, this month saw the long awaited publication of a cellular reprogramming study which restored sight to blinded mice. The significance is that they actually turned back the epi...



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November 2020 Longevity Review

Posted by Chris Pollyanna , 06 December 2020 - * * * * * · 1,875 views
supplements, alpha ketoglutarate and 4 more...
November turned out to be a bonanza for longevity studies, especially when it came to human studies of available supplements. I was in a bit of a quandary as to which studies to include in the Round-Up until I got around the problem by creating a dedicated section for them, rather than having to relegate some to the Supplementary Section. But, there were...



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October 2020 Longevity Review

Posted by Chris Pollyanna , 14 November 2020 - - - - - - · 1,973 views
supplements, covid, metformin and 2 more...
Hello and welcome again to this month’s longevity review. As COVID 19 surges once again across the northern hemisphere, I wanted to shine a bit of light on the fact that at heart COVID is yet another disease of ageing, at least in its pathological implications. After all, it is primarily the elderly who suffer complications or morbidity from it as a resul...



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September 2020 Longevity Review

Posted by Chris Pollyanna , 26 October 2020 - - - - - - · 1,969 views
supplements, metformin, nad+ and 4 more...
Hello and welcome again to this month’s longevity review. After last month’s focus on more further off longevity treatments such as gene therapy, this month the focus has shifted to more readily available drugs. Old stalwart Metformin has more evidence to its efficacy, while fellow diabetes drug Canagliflozin has been shown to increase the lifespan of mal...



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August 2020 Longevity Review

Posted by Chris Pollyanna , 05 October 2020 - - - - - - · 2,261 views
supplements, covid 19, senolytics and 2 more...
Hello and welcome again to this month’s longevity review. August was another month of progress; however, I cannot shy away from the elephant in the room, which is the failure of the Unity senolytics trial for osteoarthritis. Although without a doubt a setback, it doesn’t invalidate the entire senolytic field. There are a hundred and one different rea...



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July 2020 Longevity Review

Posted by Chris Pollyanna , 27 August 2020 - - - - - - · 2,494 views
supplements, fasting, covid19 and 2 more...
Hello and welcome again to this month’s longevity review. July was another month of progress, as yet more studies show the potential of rejuvenation using a variety of methods. To further demonstrate the variety of these methods, I’ve added a section for all the lifespan extension studies in model organisms. Most of them are using yeast or roundworms, but...



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