I ordered both and plan to try them separately. If your goal was to reduce amphetamine tolerance and restore dopamine which would you use?
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Posted 29 May 2018 - 10:25 PM
Posted 30 May 2018 - 11:42 AM
Memantine has a lot more research and anecdotal evidence for this purpose. If you'll try them both, why are you even asking? Just check for yourself which one works better.
Posted 30 May 2018 - 04:07 PM
Memantine has a lot more research and anecdotal evidence for this purpose. If you'll try them both, why are you even asking? Just check for yourself which one works better.
Posted 30 May 2018 - 04:39 PM
As far as I know, NMDA antagonists upregulate dopamine receptors. Ropinirole is a dopamine agonist, my guess is that you get some synergistic action by combining it with amphetamine, but downregulation should occur nevertheless. You might want to look into 9-me-bc, which actually heals dopaminergic neurons, people report greatly reduced amphetamine tolerance (which might be the result of its mao-b action).
Edited by Junipersun, 30 May 2018 - 04:40 PM.
Posted 30 May 2018 - 05:41 PM
As far as I know, NMDA antagonists upregulate dopamine receptors. Ropinirole is a dopamine agonist, my guess is that you get some synergistic action by combining it with amphetamine, but downregulation should occur nevertheless. You might want to look into 9-me-bc, which actually heals dopaminergic neurons, people report greatly reduced amphetamine tolerance (which might be the result of its mao-b action).
Posted 05 June 2018 - 04:49 PM
Edited by John250, 05 June 2018 - 04:49 PM.
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