Sometimes the data is more informative than the title or abstract
Merry et al, 2008. Dietary lipoic acid supplementation can mimic or block the effect of dietary restriction on life span. Mechanisms of ageing and development, 129(6), pp.341-348.
From Table 1:
median mean lifespan (days)
926 854 Ad libitum diet w/o lipoic acid
1047 1025 Fed to maintain body weight at 55% age-matched control animals
1086 1021 Ad libitum lipoic acid supplemented diet 2–6 months, then DR feeding w/o lipoic acid
Thank you darryl. I checked with some other members and what theu had to say about this. One user said this.
"I discussed this study (1) in some detail here. Basically, the benefit of adding lipoic acid to CR (a) was really rather unclear, (b] if real, was only manifested in mice that had initiated CR when young adults (6 mo/≈30 y), and (c] if real, was only manifested in mice that had been switched over from CR to AL later on in life (by blunting the loss of lifespan induced by going back on AL). Basically, if you started CR in middle age or older, and/or intend to remain on CR until rejuvenation biotechnology becomes available, the study is irrelevant to your situation."
Now according to what this user says, I am unsure whether to apply thos to myself as I began CR at 22.5 years old, about two and a half years ago, AFTER an ad libitum diet while being supplemented with R ALA 600 mg per day. I truly am havong trouble reaching a conclusion on this and whether or not I screwed myself out of CR benefits. If so, I may as well know so then I can at least not expect too much in the long run from my efforts. Thanks for your input Darryl. According to my history of diet that was supplements followed by cessation of R ALA ALONG with switching to CR diet when I did (22.5 years old), do you think it is likely that I screwed myself? And perhaps are there any studies that perhaps, albeit indirectly, show that maybe this is maybe not the case, and that oerhaps that study was flawed somehow?