LONGECITY

I have a few mutations in my dopamine genes im curious about:

https://www.selfdecode.com/gene/drd1/

https://www.selfdecode.com/gene/drd2/

https://www.selfdecode.com/gene/drd3/

https://www.selfdecode.com/gene/th/ (maybe I dont  have any mutations here)

https://www.selfdecode.com/gene/dbh/ (mutation implying  low norepinephrine but high dopamine? (not sure here)

https://www.selfdecode.com/gene/comt/ (mutation implying I have low COMT so High dopamine? dont know for sure here either)

what drug can fix each of these issues?

I can take a dopamine agonist like  pramipexole for the first 3 links (even tho Pramipexole isnt an agonist on Dopamine receptor 1 but its just an example)

what about the other 3? TH ,DBH and COMT? wtf are those and how do I fix them? Do genetic mutations in those cause low or high dopamine and do I wanna increase or decrease those?

Maybe all I need is a dopamine agonist drug that hits D1,D2 and D3 . Does hitting the D2 receptor  with drugs also hit the  D₂Sh (short) and D₂Lh (long)?

 Dopamine drug that are agonist on D1,D2 & D3?

Anybody know of a drug that is an agonist on all these 3? Bromocriptine is a agonist on them but its weak on D1. Pramipexole doesent Hit D1. cabergoline is weak on D1 also. Just for future reference , any drug that actually hits ALL these 3 dopamine receptors and are not weak? especially on D1 .

oh wow theres a whole bunch more https://www.selfhack...amine-function/

more mutations:

https://www.selfdecode.com/gene/htr2a/

https://www.selfdecode.com/gene/park2/

https://www.selfdecode.com/gene/snca/

https://www.selfdecode.com/gene/agtr2/

https://www.selfdecode.com/gene/gch1/

https://www.selfdecode.com/gene/tgfb2/

https://www.selfdeco...m/gene/slc22a3/

https://www.selfdeco...m/gene/slc22a2/

https://www.selfdeco...m/gene/slc22a1/

btw disregard the TH gene   in first post I dont have mutations in that gene.

wonder why selfhacked didnt mention the 5ht2c gene when its blocked dopamine is increased in one part of the brain ,anyway I had no mutation with it anyway.