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Plant versus animal based diets and insulin resistance, prediabetes and type 2 diabetes: the Rotterdam Study.

diet vegan ketogenic diabetes insulin resistance plant based low carb fiber carbohydrate blood sugar

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#1 misterE

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Posted 17 July 2018 - 09:11 PM

Eur J Epidemiol. 2018 Jun 8. doi: 10.1007/s10654-018-0414-8.

Plant versus animal based diets and insulin resistance, prediabetes and type 2 diabetes: the Rotterdam Study.


Vegan or vegetarian diets have been suggested to reduce type 2 diabetes (T2D) risk. However, not much is known on whether variation in the degree of having a plant-based versus animal-based diet may be beneficial for prevention of T2D. We aimed to investigate whether level of adherence to a diet high in plant-based foods and low in animal-based foods is associated with insulin resistance, prediabetes, and T2D. Our analysis included 6798 participants from the Rotterdam Study (RS), a prospective population-based cohort in the Netherlands. Dietary intake data were collected with food-frequency questionnaires at baseline of three sub-cohorts of RS. We constructed a continuous plant-based dietary index assessing adherence to a plant-based versus animal-based diet. Insulin resistance at baseline and follow-up was assessed using homeostasis model assessment of insulin resistance (HOMA-IR). Prediabetes and T2D were collected from general practitioners' records, pharmacies' databases, and follow-up examinations in our research center until 2012. We used multivariable linear mixed models to examine association of the index with longitudinal HOMA-IR, and multivariable Cox proportional-hazards regression models to examine associations of the index with risk of prediabetes and T2D. During years of follow-up, we documented 928 prediabetes cases and 642 T2D cases. After adjusting for sociodemographic and lifestyle factors, a higher score on the plant-based dietary index was associated with lower insulin resistance, lower prediabetes risk and lower T2D risk. After additional adjustment for BMI, associations attenuated and remained statistically significant for longitudinal insulin resistance and T2D risk, but no longer for prediabetes. In conclusion, a more plant-based and less animal-based diet may lower risk of insulin resistance, prediabetes and T2D. These findings strengthen recent dietary recommendations to adopt a more plant-based diet.


#2 mikey

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Posted 21 October 2018 - 12:25 AM

While this says "more plant-based" diet, some people will interpret that as meaning "no animal products."

After studying nutrition for longevity for over 40 years, the summation of hundreds or thousands of studies points to an optimal longevity diet as being one that features a wide-range of plant-foods as the majority of consumption with a lesser amount of truly natural animal-based foods, such as 100% organic grass-fed, pasture-raised beef or dairy products to benefit from the nutrients that are not found in plants, or there will be nutritional deficiencies of multiple essential nutrients.

So, to be clear, is the point of this forum to define an optimal diet to reduce the risk of Type II diabetes as a diet that contains ONLY plant foods?

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Also tagged with one or more of these keywords: diet, vegan, ketogenic, diabetes, insulin resistance, plant based, low carb, fiber, carbohydrate, blood sugar

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