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A Question About Anti-Glycation Effects


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#1 eighthman

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Posted 07 December 2018 - 03:15 AM

The latest Life Extension has an article about preventing AGE/ crosslink problems using various supplements.


It is believed that crosslinked proteins created by glycation reactions cannot be removed. However, it is suggested that carnosine

may reduce wrinkles or that bentfotiamine may help diabetic nerve issues.


My question is that some of these improvements look structural rather than just preventative.  You lose some wrinkles, some diabetic damage and so on.

Is there an explanation for these?  Could there be changes in crosslinked structures that haven't been noticed ?


By example, I understand that it was held that humans have no ability to synthesize vitamin C in their bodies - but this is now being questioned. Surprises pop up sometimes......I hope for one involving crosslinks/glycation.

#2 dazed1

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Posted 07 December 2018 - 07:24 AM

high glucose/insulin/inflammation destroys collagen = done.

Edited by dazed1, 07 December 2018 - 07:24 AM.

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#3 eighthman

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Posted 07 December 2018 - 12:46 PM

I don't think you get the point.  Wrinkles and other structural crosslink features appear.  You take a supplement such as those above and some of those features disappear.

You have reduced glycation but something more seems to have occurred.

Also tagged with one or more of these keywords: glycation

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