• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
              Advocacy & Research for Unlimited Lifespans


Is procrastination in my genes?

comt dopamine procrastination

  • Please log in to reply
2 replies to this topic
⌛⇒ support MITOMOUSE via LongeCity!

#1 Clavius

  • Guest
  • 46 posts
  • 3
  • Location:Netherlands
  • NO

Posted 07 February 2019 - 09:46 AM

Apparently I have the rs4680(G;G) val/val gene. High COMT which means low dopamine. I have the (related?) rs909525(G;G). But I also have the rs6323(T;T) for reduced MAOA activity. 


Is this the reason why I don't notice anything from modafinil? And why I only notice methylphenidate when I dose dangerously high levels?

#2 chrisv

  • Guest
  • 15 posts
  • 2
  • Location:New York

Posted 06 September 2019 - 05:29 PM

Yes. I wrote a in-depth post on this on another forum.



Any time we genetically engineer a mouse to have low dopamine genes, it's lazy. It refuses to exercise.

Did you check the other genes in your DA pathway? There may be more (DAT, DRD2, MAO-B, MTHFR)

My suggestion is to inhibit MAO-A and COMT. But also look into other genes causing this problem. This company does full genetic testing of the entire dopamine pathway and sends back a full in depth report. https://www.genedsystems.com

The addiction one is the one that does the full dopamine pathway.

Click HERE to rent this GENETICS advertising spot to support LongeCity (this will replace the google ad above).

#3 Clavius

  • Topic Starter
  • Guest
  • 46 posts
  • 3
  • Location:Netherlands
  • NO

Posted 06 September 2019 - 09:05 PM

Thanks for responding. I got the DRD2 also. I'm indeed going to focus on MAO-A and COMT inhibition. I don't want to be like this.

  • Agree x 1

sponsored ad

  • Advert
Advertisements help to support the work of this non-profit organisation. [] To go ad-free join as a Member.

Also tagged with one or more of these keywords: comt, dopamine, procrastination

0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users