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Crowfunding Immunization of Alz Research

alz alzheimer alzheimers disease crowdfunding

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#1 noot_in_the_sky

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Posted 07 April 2019 - 03:28 PM


I was looking over Experiment.com, and saw that someone is looking for money to do some research.  Does anyone have any experience backing up research on this site?

 

Site:

https://experiment.c...eimer-s-disease

 

 

 

 

What are the goals of the project?

 

Our hypothesis is auto-antibodies made against injected MetO-rich protein (antigen) could be used as a treatment for AD through elimination of brain MetO-Aβ (suggested to be an early-oxidized form of Aβ) and possibly other MetO-containing proteins that mediate Aβtoxicity. Our overreaching goal is to determine the ability of the antigen to alleviate memory-related phenotypes associated with AD. The APP/PS1 mice show deficiencies starting at 6 months of age. Accordingly, the antigen will be administrated at age of 3-4 months (3 injections every 2 weeks). Then, the cognitive functions of the control and experimental mouse groups will be monitored at 8, 10 and 12 months of age for their cognitive abilities (We will use Y maze spontaneous alternation, and Morris water maze tests).

 







Also tagged with one or more of these keywords: alz, alzheimer, alzheimers disease, crowdfunding

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