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Crowfunding Immunization of Alz Research

alz alzheimer alzheimers disease crowdfunding

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#1 noot_in_the_sky

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Posted 07 April 2019 - 03:28 PM

I was looking over Experiment.com, and saw that someone is looking for money to do some research.  Does anyone have any experience backing up research on this site?








What are the goals of the project?


Our hypothesis is auto-antibodies made against injected MetO-rich protein (antigen) could be used as a treatment for AD through elimination of brain MetO-Aβ (suggested to be an early-oxidized form of Aβ) and possibly other MetO-containing proteins that mediate Aβtoxicity. Our overreaching goal is to determine the ability of the antigen to alleviate memory-related phenotypes associated with AD. The APP/PS1 mice show deficiencies starting at 6 months of age. Accordingly, the antigen will be administrated at age of 3-4 months (3 injections every 2 weeks). Then, the cognitive functions of the control and experimental mouse groups will be monitored at 8, 10 and 12 months of age for their cognitive abilities (We will use Y maze spontaneous alternation, and Morris water maze tests).


Also tagged with one or more of these keywords: alz, alzheimer, alzheimers disease, crowdfunding

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