Hello:
I just I have discovered this company PatchMD that sells patches with vitamins. In particular I like it:
https://www.patchmd....ical-Patch.html
What do you think about it?
Regards.
Andrew
Posted 28 October 2019 - 01:46 PM
Hello:
I just I have discovered this company PatchMD that sells patches with vitamins. In particular I like it:
https://www.patchmd....ical-Patch.html
What do you think about it?
Regards.
Andrew
Posted 28 October 2019 - 04:53 PM
Someone has rated it as "Pointless, Timewasting". I absolutely disagree. If there is another way to take the supplements, it is well worth to know.
So, if somebody has something good or bad to tell about this method or company, be welcome to share with us.
Posted 29 October 2019 - 01:28 PM
I seriously question how much of these compounds are they able to deliver transdermally. Most vitamins and supplements are not dosed in micrograms. A typical dose is in the range of 10s to 100s of milligrams. It's not important how much of each compound is in each patch, but rather how much makes it across the dermal barrier and is delivered effectively. If they have data on that I'd love to see it.
Also, some of those compounds are readily available orally (like vitamin C). I just don't see any point in dosing them transdermally.
Posted 29 October 2019 - 04:10 PM
I seriously question how much of these compounds are they able to deliver transdermally. Most vitamins and supplements are not dosed in micrograms. A typical dose is in the range of 10s to 100s of milligrams. It's not important how much of each compound is in each patch, but rather how much makes it across the dermal barrier and is delivered effectively. If they have data on that I'd love to see it.
Also, some of those compounds are readily available orally (like vitamin C). I just don't see any point in dosing them transdermally.
I think it is a good point if it means to avoid the intake of 8 to 12 different vitamins or supplements. It could be easy to have all the entire lot of supplements in a single patch a day.
About how much is it absorb, I think it is pretty steady the amount, since other drugs are administered that way under a medical point of view.
I will investigate more and inform this thread.
Posted 29 October 2019 - 05:30 PM
I think you are missing the reason for my skepticism.
Systemic drugs (as opposed to local drugs like a lidocaine patch) that are administered via transdermal patch, for example fentanyl, typically have very low effective doses. Fentanyl for instance come in doses of 12 to 75 micrograms.
I am just very skeptical that you're going to move 100's of milligrams of any of these compounds across the skin which is designed to be relatively impermeable such that they go systemic. That's a lot of material you're trying to move across the dermal barrier.
Yeah, nice idea to slap a patch on instead of taking a half dozen pills, but if it doesn't work, it doesn't work.
I'm certainly open to evidence to the contrary. Perhaps the manufacturer of that patch has some data on plasma levels achieved of these compounds via their patch delivery system. Absent that, I wouldn't spend money on something that isn't even proven to get these supplements into your system.
Posted 29 October 2019 - 06:06 PM
in 1 word:garbajeeeeeeeeeeeeeeeeeeeeeeee
Posted 29 October 2019 - 06:52 PM
I think you are missing the reason for my skepticism.
Systemic drugs (as opposed to local drugs like a lidocaine patch) that are administered via transdermal patch, for example fentanyl, typically have very low effective doses. Fentanyl for instance come in doses of 12 to 75 micrograms.
I am just very skeptical that you're going to move 100's of milligrams of any of these compounds across the skin which is designed to be relatively impermeable such that they go systemic. That's a lot of material you're trying to move across the dermal barrier.
Yeah, nice idea to slap a patch on instead of taking a half dozen pills, but if it doesn't work, it doesn't work.
I'm certainly open to evidence to the contrary. Perhaps the manufacturer of that patch has some data on plasma levels achieved of these compounds via their patch delivery system. Absent that, I wouldn't spend money on something that isn't even proven to get these supplements into your system.
I understand but do not share your point.
In this websites it is explain something about it.
https://www.ncbi.nlm...les/PMC4695828/
https://en.wikipedia...ansdermal_patch " they are only useful for fat-soluble and relatively small molecular weight drugs, possibly to pass through the cornea layer"
Despite missing some technical information about how works those patches and others similar, I found out many and more and more drugs are available by via transdermical. Possibly very soon we will be using them instead of pills (also have a lot of disadvantages if not so many yet).
I will keep looking for this interesting method.
Posted 29 October 2019 - 07:00 PM
in 1 word:garbajeeeeeeeeeeeeeeeeeeeeeeee
May be it will not word yet or not with all the supplements we would wish to, but some patches works (see below, if you do not mind).
Pitifully, the only garbage is your reply, empty, lack of effort to justify and careless.
Popular uses
Posted 29 October 2019 - 10:10 PM
so you advertise for this website? sorry that for time wasted on my 1 word
yea i can t say anything bad about the work of others and it is good work but what i meant is compared to other choices and price/what you get it ranks very low we can t give medals for "7th place" thats the reality mate
Posted 29 October 2019 - 10:34 PM
so you advertise for this website? sorry that for time wasted on my 1 word
yea i can t say anything bad about the work of others and it is good work but what i meant is compared to other choices and price/what you get it ranks very low we can t give medals for "7th place" thats the reality mate
I do not advertise... if it is all you can see...
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