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EVEROLIMUS

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#1 poonja

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Posted 08 January 2020 - 12:00 AM


Does anyone have any experience with everolimus as compared to sirolimus/rapamycin.  I believe that it is enveloped to accomplish similar things as sirolimus.  However, I believe that is somewhat stronger and has a shorter half life which would, I believe, call for a somewhat different dosing schedule.  I am asking as I may have an opportunity to acquire a gram on powder form making precise dosing somewhat problematic unless it lends itself to volumetric dosing.



#2 sub7

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Posted 09 January 2020 - 06:12 PM

I know you are looking for personal user experiences, which is what I too would like to hear about. 

While waiting for those here is a little something to consider

https://www.ncbi.nlm...pubmed/17645716

Basically, Everolimus was equally effective in organ rejection as Sirolimus, bur Ev had less of a negative effect on blood lipids and was therefore superior (in just this aspect)

 

For a broad discussion of differences this is excellent

https://www.ncbi.nlm...les/PMC6053318/


Edited by sub7, 09 January 2020 - 06:51 PM.


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#3 poonja

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Posted 09 January 2020 - 11:18 PM

Thank you.



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