Are you really ready to just throw up your hands and accept another leading cause of pneumonia related deaths to an immunologically naive population? Seems to me on the contrary a fine time for rethinking our dirty habits and ways of life.
A: No dirty habits and ways of life. (honesty, harmlessness, etc.)
B: A good scientist always tries to disprove his own thesis to see if it holds water.
Since we are both not trained scientists and both are better in tearing an opposing theory apart, I suggested to wait for the WHO's data, so you also have a better job at their inaccuracies, methology and definitions.
However, your study is actually perfect in many respects: showing the limitation of any precise numbering - also applying to the WHO's - and it's big difference in definition, of how they come to their number compared of how it is done with covid-19.
Many of the remainders are tuberculosis and unrelated pathogens—which are less contagious and primarily caught in the environment—wouldn't see as drastic a reduction in deaths due to the lockdowns.
Tuberculosis being a dangerous infectious disease itself, therefore tested for and many places very thightly registrated, and accordingly given as a separate catergory in WHO mortality statistic, couldn't ever have been confused with pneumonia.
2018 WHO mortality rate:
Cause of Death Rank Deaths
Coronary Heart Disease 1 9,405,008
Stroke 2 5,765,313
Lung Disease 3 3,032,444
Influenza and Pneumonia 4 2,947,050
Alzheimers/Dementia 5 1,976,848
Lung Cancers 6 1,696,334
Diabetes Mellitus 7 1,582,816
Road Traffic Accidents 8 1,399,255
Diarrhoeal diseases 9 1,382,508
Tuberculosis 10 1,292,603
Liver Disease 11 1,247,237
Kidney Disease 12 1,172,181
Low Birth Weight 13 1,012,063
HIV/AIDS 14 1,011,748
Hypertension 15 893,402
Liver Cancer 16 818,785
Suicide 17 788,851
Colon-Rectum Cancers 18 786,962
Stomach Cancer 19 755,968
Birth Trauma 20 678,355
Rank 4 is influenza and pneumonia with almost 3 million deaths in 2018 (still to be confirmed with the original data).
Rank 10 is Tuberculosis with about 1.3 millions deaths.
However, I readily admit that in your lanced-study there really isn't any indication they excluded pneumonia from their influeza estimate. Different to Hip's secondary source.
So let's take a look at the actual study:
Estimates of global seasonal influenza-associated respiratory mortality: a modelling study
Published:December 13, 2017 DOI:https://doi.org/10.1...6736(17)33293-2
Summary Background
Estimates of influenza-associated mortality are important for national and international decision making on public health priorities. Previous estimates of 250 000–500 000 annual influenza deaths are outdated. We updated the estimated number of global annual influenza-associated respiratory deaths using country-specific influenza-associated excess respiratory mortality estimates from 1999–2015.
Methods
We estimated country-specific influenza-associated respiratory excess mortality rates (EMR) for 33 countries using time series log-linear regression models with vital death records and influenza surveillance data. To extrapolate estimates to countries without data, we divided countries into three analytic divisions for three age groups (<65 years, 65–74 years, and ≥75 years) using WHO Global Health Estimate (GHE) respiratory infection mortality rates. We calculated mortality rate ratios (MRR) to account for differences in risk of influenza death across countries by comparing GHE respiratory infection mortality rates from countries without EMR estimates with those with estimates. To calculate death estimates for individual countries within each age-specific analytic division, we multiplied randomly selected mean annual EMRs by the country's MRR and population. Global 95% credible interval (CrI) estimates were obtained from the posterior distribution of the sum of country-specific estimates to represent the range of possible influenza-associated deaths in a season or year. We calculated influenza-associated deaths for children younger than 5 years for 92 countries with high rates of mortality due to respiratory infection using the same methods.
Now that raises of course the interesting question, why they needed to exptrapolate from only 33 countries? - And by which methology the WHO data in comparison could estimate it for each of the 200 something countries on the earth? - Will be really interesting to see the WHO methology and definitiions.
Findings
EMR-contributing countries represented 57% of the global population. The estimated mean annual influenza-associated respiratory EMR ranged from 0·1 to 6·4 per 100 000 individuals for people younger than 65 years, 2·9 to 44·0 per 100 000 individuals for people aged between 65 and 74 years, and 17·9 to 223·5 per 100 000 for people older than 75 years. We estimated that 291 243–645 832 seasonal influenza-associated respiratory deaths (4·0–8·8 per 100 000 individuals) occur annually. The highest mortality rates were estimated in sub-Saharan Africa (2·8–16·5 per 100 000 individuals), southeast Asia (3·5–9·2 per 100 000 individuals), and among people aged 75 years or older (51·3–99·4 per 100 000 individuals). For 92 countries, we estimated that among children younger than 5 years, 9243–105 690 influenza-associated respiratory deaths occur annually.
Interpretation
These global influenza-associated respiratory mortality estimates are higher than previously reported, suggesting that previous estimates might have underestimated disease burden. The contribution of non-respiratory causes of death to global influenza-associated mortality should be investigated.
Funding
None.
In The Lancet, Danielle Iuliano and colleagues 1 have attempted to estimate the global mortality burden of seasonal influenza. This study provides a much needed update to the often cited but unsubstantiated WHO-attributed estimate of 250 000–500 000 annual influenza deaths. The authors used country-specific, influenza-associated excess respiratory mortality estimates from 1999 to 2015, to calculate a new estimate of 291 243–645 832 seasonal influenza-associated respiratory deaths per year (4·0–8·8 per 100 000 individuals). Although these new estimates indicate that influenza-associated mortality has increased, they might underestimate the true mortality burden, which would also include deaths attributable to non-respiratory causes. 2
Finally the CDC press-release to this study does get more specific, in which deaths would also be included attributable to non-resperatory causes:
According to new estimates published today, between 291,000 and 646,000 people worldwide die from seasonal influenza-related respiratory illnesses each year, higher than a previous estimate of 250,000 to 500,000 and based on a robust, multinational survey.
The new estimate, from a collaborative study by CDC and global health partners, appears today in The Lancet. The estimate excludes deaths during pandemics.
“These findings remind us of the seriousness of flu and that flu prevention should really be a global priority,” says Joe Bresee, M.D., associate director for global health in CDC’s Influenza Division and a study co-author.
The new estimates use more recent data, taken from a larger and more diverse group of countries than previous estimates. Forty-seven countries contributed to this effort. Researchers calculated annual seasonal influenza-associated respiratory deaths for 33 of those countries (57 percent of the world’s population) that had death records and seasonal influenza surveillance information for a minimum of four years between 1999 and 2015. Statistical modeling with those results was used to generate an estimate of the number of flu-associated respiratory deaths for 185 countries across the world. Data from the other 14 countries were used to validate the estimates of seasonal influenza-associated respiratory death from the statistical models.
Poorest nations, older adults hit hardest by flu
Researchers calculated region-specific estimates and age-specific mortality estimates for people younger than 65 years, people 65-74 years, and people 75 years and older. The greatest flu mortality burden was seen in the world’s poorest regions and among older adults. People age 75 years and older and people living in sub-Saharan African countries experienced the highest rates of flu-associated respiratory deaths. Eastern Mediterranean and Southeast Asian countries had slightly lower but still high rates of flu-associated respiratory deaths.
Despite World Health Organization recommendations to use flu vaccinationexternal icon to help protect people in high-risk populations, few developing countries have seasonal flu vaccination programs or the capacity to produce and distribute seasonal or pandemic vaccines.
Global flu surveillance protects all nations, including U.S.
CDC works with global partners to improve worldwide capacity for influenza prevention and control. CDC has helped more than 60 countries build surveillance and laboratory capacity to rapidly detect and respond to influenza threats, including viruses with the potential to cause global pandemics. These efforts, along with technical support, has helped some partners generate estimates of influenza-associated deaths, which contributed to this global effort.
Global surveillance also provides the foundation for selecting the viruses used to make seasonal flu vaccines each year. This helps improve the effectiveness of flu vaccines used in the United States. Global surveillance also is crucial to pandemic preparedness by identifying viruses overseas that might pose a human health risk to people in the United States.
“This work adds to a growing global understanding of the burden of influenza and populations at highest risk,” says CDC researcher Danielle Iuliano, lead author of The Lancet study. “It builds the evidence base for influenza vaccination programs in other countries.”
The study authors note that these new estimates are limited to flu-associated respiratory deaths and therefore may underestimate the true global impact of seasonal influenza. Influenza infection can create or exacerbate other health factors which are then listed as the cause of death on death certificates, for example cardiovascular disease, diabetes, or related complications. Additional research to estimate non-respiratory causes of flu-associated deaths are ongoing.
There you have it: Other than the covid-19 death numbers always knowingly did, the yearly influenza mortality estimate of this study explicitly excludes co-morbitities like CVD and diabetes!
Therefore comparing the influenza mortality of this estimate, to covid-19 deaths with expicitly includes co-morbitities, is really comparing apples to oranges.
If we believe all study-results that covid-19 deaths includes over 90% of comorbities in CVD, diabetes and obesity, we have to substract just 90% of these comorbities from the yearly influenza-death-estimate of your study:
Today: 529,596 x 0.1 = 52 959 pure covid-19 deaths after about half a year, versus comparable 646 000 influnzia-deaths in this study!
Therefore not even only 3 times less worse than the yearly influenzia and pneumonia mortality by the WHO data, but according to the by you provided study actually about 6 times less worse.
Edited by pamojja, 04 July 2020 - 11:23 AM.