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Trimipramine

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#1 alpha2A

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Posted 24 November 2020 - 05:35 PM


Hi all,

 

I was just wondering if anyone else here is taking trimipramine or has experience with it?

 

Trimipramine is a tricyclic antidepressant (TCA) traditionally marketed under the name Surmontil.

 

I find it helps me "surmount" my depression, more than any other drug classified as "antidepressant", and I've tried *a lot*.  In my experience, it is also a better antipsychotic than even clozapine.  While using trimipramine, I have come so far that I can't call the depression a "mood" disorder any more.  I am just somewhat apathetic.

 

One particularly unusual action of trimipramine is to block histamine H2-receptors.  I think this may underlie some of its antidepressant action.

 

-alpha2A

 







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