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#1 alpha2A

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Posted 24 November 2020 - 05:35 PM

Hi all,


I was just wondering if anyone else here is taking trimipramine or has experience with it?


Trimipramine is a tricyclic antidepressant (TCA) traditionally marketed under the name Surmontil.


I find it helps me "surmount" my depression, more than any other drug classified as "antidepressant", and I've tried *a lot*.  In my experience, it is also a better antipsychotic than even clozapine.  While using trimipramine, I have come so far that I can't call the depression a "mood" disorder any more.  I am just somewhat apathetic.


One particularly unusual action of trimipramine is to block histamine H2-receptors.  I think this may underlie some of its antidepressant action.




Also tagged with one or more of these keywords: drugs

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