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Homocysteine Increases During Aging, But Can Be Reduced With Diet And Targeted Supplementation

homocysteine aging

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#1 Michael Lustgarten

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Posted 09 May 2021 - 10:24 AM



Papers referenced in the video:
Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway: https://pubmed.ncbi....ih.gov/32130...
Comparison of the effects of nicotinic acid and nicotinamide degradation on plasma betaine and choline levels: https://pubmed.ncbi....ih.gov/27567...
Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study: https://pubmed.ncbi....ih.gov/7474221/
Total plasma homocysteine values among elderly subjects: findings from the Maracaibo Aging Study: https://pubmed.ncbi....ih.gov/16959...
Hyperhomocysteinemia as a Risk Factor and Potential Nutraceutical Target for Certain Pathologies: https://www.ncbi.nlm...gov/pmc/arti...
Hyperhomocysteinemia and risk of incident cognitive outcomes: An updated dose-response meta-analysis of prospective cohort studies: https://pubmed.ncbi....ih.gov/30826...
Association between Homocysteine Levels and All-cause Mortality: A Dose-Response Meta-Analysis of Prospective Studies: https://www.nature.c...ticles/s4159...


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#2 albedo

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Posted 16 May 2021 - 09:57 AM

My data shows clearly a trend downward since I start overall supplementation with the B complex with a more market effect when I started using NR. However, I am still at ~10 and find hard to achieve more. I am not homozygous for MTHFR C677T (there is only 30% of normal enzyme function) and also looked at the CBS path. Thank you for your new video. I recollect a lot of info on homocysteine on this Forum you might find interesting.

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