Did you know that human lifespan has a hard ceiling, not set by cancer or heart disease? Even when disease is avoided and even with perfect biomarkers, it runs into a hard biological limit —the irreversible motor neuron loss.
Humans are born with ~150,000 motor neurons, and lose them gradually with old age:
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Before age 60, you lose ~0.5% per year
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After age 60, you lose ~3% per year
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Age 75 - only ~50% functional units
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Age 100 - only ~20% functional units
At which point, frailty and neuromuscular failure dominate death. And once it begins to fail, no amount of optimization or lifestyle change can fully compensate.
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