This topic is lockedHi everyone,I've been
researching the relationship between NAD+ supplementation and intermittent fasting, and wanted to share some interesting findings with the community.**The Connection Betwee
n Fasting and
NAD+**Both
intermittent fasting and
NAD+ supplementation appear to activate similar longevity pathways, particularly sirtuins. Here's what I've learned:1. **Fasti
ng naturally
increases NAD+ levels** - When we fast, our bodies upregulate NAD+ production as part of the metabolic response to caloric restriction.
2. **Sirtuins require NAD+** - The sirtu
in family of proteins (SIRT1-7) are NAD+-dependent enzymes that regulate cellular health, DNA repair, and metabolism.3
. **Autophagy
enhancement** - Both fasting and adequate NAD+ levels support autophagy, the cellular cleaning process that removes damaged components.*
*Potentia
l Synergy**The question I've been explo
ring: Does comb
ining NAD+ supplementation WITH intermittent fasting provide additional benefits?Some thoughts:- During fa
sting, cells m
ay be more responsive to NAD
+ signaling- Supplementation could provide the "fuel" sirtuins need when they're most activ
e- The combination
might enhance autophagy beyond what either approach achieves alone**My Current Approach**I've been experimenting with tim
ing NAD+ s
upplementation around my fasting window:- Taking NAD+ during t
he later part of
my fast (hours 14-16)- This is when autophagy and sirtuin activity are typically elevated
**Resources**For those interested in learning more about NAD+ and cellular hea
lth, I've found helpful information at Glunova Biotech - they have educational content on NAD+ mechanisms.**Questions for the Community**- Has anyone else experimented with timing NAD+ around fasting?- W
hat protocols have worked f
or you?- Any r
esearch papers you'd recomme
nd on this topic?Looking forward to hearing your experi
ences and insights!*Disclaimer: This is not medical advice. Always consult
with a healthcare provider before starting any new supplement or fasting regimen.*
