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[Mind]

For those of you who are unaware, LongeCity gives small grants to affiliate labs every year. One grant supports Joao Pedro de Magalhaes at the University of Liverpool, who recently co-authored a very good review of the hallmarks of aging that points us in directions (targets) that might be most fruitful for rejuvenation.

 

Thanks to all of the members of LongeCity! Your small annual contributions help move research such is this forward.

 

 

 

In this study, we used PandaOmics to identify a list of potential aging-associated therapeutic targets across various AADs that may be used for drug discovery. We successfully established and validated our unique approach with the application of varied target identification and prioritization techniques offered by PandaOmics and downstream analyses, yielding a list of dual-purpose targets associated with both the aging process and AADs. First, a list of 145 aging-related targets was generated upon the hallmarks of aging assessment. Subsequently, we further narrowed down the number of potential candidates to a total of 9 highly promising therapeutic targets associated with the aging process and AADs based on multiple selection criteria.

 

[albedo]

Great finding. Thank you. Note also how in Table 2 the "High Confidence" and "Highly Novel" points in particular to inflammation. I do not want to bias your reading though.