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[osris]

Can nattokinase cause an existing clot to dislodge leading to a potential stroke? Or does it dissolve clots fully before the clot is "washed away" by the blood?

[osris]

ChatGPT has provided the answer:

 

"There is no evidence or mention of Nattokinase causing an existing clot to dislodge into the bloodstream. On the contrary, Nattokinase is known for its fibrinolytic activity, which means it can dissolve blood clots. Studies have shown that Nattokinase has potent fibrinolytic effects, leading to the breakdown of fibrin, an insoluble protein involved in blood clot formation. Additionally, it inhibits platelet aggregation, which helps in thinning the blood and facilitating clot dissolution.

 

The safety profile of Nattokinase has been evaluated in various studies, including acute toxicity and genotoxicity evaluations, and it has been found to have a favorable safety profile. In preclinical safety studies, Nattokinase did not show any mutagenic activity, and it demonstrated no evidence of potential to induce chromosome aberrations. There were no observed toxicological signs even at a high concentration, indicating its safety even at higher doses.

 

In summary, there is no evidence to suggest that Nattokinase causes existing clots to dislodge into the bloodstream. On the contrary, Nattokinase's mechanism of action involves dissolving blood clots, making it a potentially beneficial agent for the prevention and treatment of cardiovascular diseases [3] [4] [7].