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After 5 months of tretinoin use


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#61 Phoebus

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Posted 02 October 2018 - 10:24 PM

 

 

The first link you sent me looks slightly sketchy to be honest - have you purchased anything from them? Do you know if it's legit?

 

 

 

just bought some HA yesterday from there, will let you know if its okay when it arrives 


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#62 Phoebus

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Posted 03 October 2018 - 02:46 AM

okay I found a study that looks at using HMW HA vs. LMW HA on skin. Great study. Basically concludes LMW HA is safe and effective. 

 

 

With the results of the present study it was clearly demonstrate that HA offers not only beneficial effects to the skin but also that these effects can be controlled by varying the molecular size. It was found that LMW HA provides better penetration abilities than larger sized HA and, accordingly, influenced the expression of many genes including those contributing to keratinocyte differentiation and formation of intercellular tight junction complexes which are reported to be reduced in aged and photodamaged skin. These different molecular properties of high and low MW HA generated different in-vivo effects with pronounced moisturization and elasticity properties shown for high MW HA and marked reduction of wrinkles demonstrated for LMW HA´s. The increased activity at decreasing molecular weight can be explained by the more efficient skin penetration of the smaller HA molecules. These data show for the first time that topical application of LMW HA improves skin functioning and provides anti-aging effects which could be achieved by strengthening its penetration abilities based on decreasing the molecular size.

https://pdfs.semanti...dd7dbda90ca.pdf


Edited by Phoebus, 03 October 2018 - 03:34 AM.


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#63 S_89

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Posted 05 October 2018 - 07:52 PM

okay I found a study that looks at using HMW HA vs. LMW HA on skin. Great study. Basically concludes LMW HA is safe and effective. 

 

https://pdfs.semanti...dd7dbda90ca.pdf

 

Interesting. Thanks a lot.

 

I have found a product on DECIEM website that contains many differing molecular weights so I think I'll try this but let me know how you get on with yours.

Also, do you have the link to the guy on Youtube that stimualted fat growth with HA?

 

I am looking into fat transfer as I have a great local surgeon that specializes in eye fat transfer and I'm feeling more positive about things generally but please keep sharing if you find anything else about HA.

 

A really positive study I found about mixed molecular weight HA enhancing fat grafting was:

 

https://www.ncbi.nlm...pubmed/29179206

 

Please keep sharing if you experience any results.


Edited by S_89, 05 October 2018 - 07:55 PM.

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