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Ridiculously large piracetam doses


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#1 Wurzel Bagman

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Posted 04 July 2010 - 03:27 AM


I started taking this substance back in April. At the time i had no scale or means to find out how much piracetam i was actually consuming. I would use a regular sized tablespoon from my drawer and mix anywhere from 1/4 to heaping spoonfuls with water and not really pay much attention to dose.

For a few days i didn't notice much difference aside from clarity of vision and feeling very sleepy at times. Then I started to get what seemed like limitless energy. I felt very much alive and full of life. My eyes gleamed, shiny and bright as continued taking large doses of this stuff.

I began to feel what felt like almost super human abilities. I was noticing everything in my surroundings in much a different way. I would walk into a crowded area and scan everyone in my vicinity. At home, i was able to pickup and listen to conversations that took place far away in distant rooms. I took a few basic hearing tests online and was able to hear very high frequencies (maxing out my headphones 22hz) At my part time job i was able to work faster, think crystal clearly and perform tasks with great ease.

My interest in every aspect of life skyrocketed. I found myself engaging in conversation with people who i previously would never see myself associating with. Learning became very enjoyable and i learnt to touch type with the Dvorak keyboard layout.

I felt i was becoming faster and faster at thinking and doing. My vision became a thing of beauty with it's crisp vibrant color. It became a true joy to merely glance around in any setting.

I read many of Isochroma's posts and can understand dead on why he said some of the things he did and could relate on many fronts.

Then in the mail arrived the empty capsules i decided to get since my cocktails weren't exactly the most appetizing elixirs. I manually filled pills and took them when outside my home. I still took my unmeasured drinks of raw energy in the morning. Then i slowly tapered off the mixing of the drinks opting for the quick and painless capsule form. Over a few weeks my experiences became to decline and i found myself less vivacious and becoming more "human" again. I blamed it on life circumstance changes and becoming "used" to the piracetam state. I was taking roughly 10 capsules on average over the course of a day which i figured was plenty.

Up until a few days ago when i bought a scale i had no idea how much i was actually consuming. Low and behold my heaping spoonful doses were an insane 12g!! (the pills roughly 800mg).

I would estimate that at the start i was taking roughly 24-36grams per day and man was it great :)

I drank an average of 4 litres a day as i was always thirsty and had water on hand at all times.

When i found out how much i was actually consuming it frightened me. But after coming down to more reasonable doses i think i want to go back to that original state of (unhuman) being.

I just had another 12g cocktail of life (which i havent had in months) and im feeling the life flow back into me.

Does anyone have any experiences of mega dosing to share? Are there any major risks associated with it? (i went about a month on my initial mega dose spree) To people that claim the stuff doesn't do much, have you tried 12gram doses?
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#2 unregistered_user

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Posted 04 July 2010 - 03:57 AM

I regularly take 1g doses a time or two per day and notice subtle enhancements. I attempted a 3g dose and it put me to sleep within 15 minutes. A sleep that lasted 3-4 hours. After trying the 3g dose (which I felt was HIGH) a few times with the same lethargic results, I decided that normal or even micro-sized doses were more my speed. I never dared to go as high as 12g as I could only imagine what effect that might have based on my experience with 3g.

How is it you wound up taking 12g in the beginning without knowing that it was so high? At 12g did you maintain your "super human" enhancements or did you find the results to be hit or miss? By the way, if you order piracetam from smartpowders (which is where I got my first tub) the included scoop measures 1g of Piracetam.

How much do you weigh? Are you taking other supplements? Can you give us any other useful/additional info? I might be willing to try 12g if I knew more about your situation when taking it. Any negative side effects? What happens to you if you take 800mg to 1g?

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#3 health_nutty

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Posted 04 July 2010 - 04:03 AM

I took 4G as an attack dose when I first started taking piracetam and the results were NOT good. I was extremely irritable with no increase of cognitive abilities.

#4 unregistered_user

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Posted 04 July 2010 - 04:06 AM

Is it likely, or even possible, that somehow such an outrageously high dose such as 12g could bring about such positive effects if if a typically regarded high dose of around 3-4g creates irritability. What ever happened to the bell-response curve that everyone so often talks about? You'd think a 12g dose would put you smack dab on the ineffective curve of the bell.

#5 Wurzel Bagman

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Posted 04 July 2010 - 04:14 AM

My scoop from SP actually ended up being half way down the container XD The first racetam i ever had was pramiracetam. It knocked me out asleep after just one pill. Once i got the piracetam i was happy to find it didn't knock me out like the pram. I started having small spoons but decided i wanted more and more just to see what it would be like. So what was once small mounds of powder on the tip of the spoon soon became heaping tablespoons. My super human abilities were sustained when i was taking the big doses. In fact, everyday I maintained the megadoses i felt it more and more. I weigh a mere 130 lbs.The only real side effect i got was the occasional headache to which a capsule of lecithin would soon cure. I suppose my keen interest in everything did lead to sleeping at odd hours and taking naps more. But overall i haven't had any bad experiences.

I'll be taking these large doses again regularly and keep you posted!

#6 Wurzel Bagman

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Posted 04 July 2010 - 04:19 AM

People talk about this "bell curve" as if it's something that's proven. Can anyone cite from where it even came though? Perhaps the reason those that have 4 g at once have a bad time is that they are far from conditioned to being able to handle that much. I believe my initial trial of pramiracetam conditioned me to being able to cope with large amounts of piracetam (it is 8-30 times stronger is it not?)

#7 unregistered_user

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Posted 04 July 2010 - 04:32 AM

Interesting. I'll try a large dose in the next day or two and let you know what my results are. I've been taking piracetam at 1g or so every day for almost a couple of months. I'd love to experience what you did. Are you taking piracetam with anything other than a choline source? Are you sure your results can be attributed to it alone or is there a synergy at work? I'm taking a multi, choline bit, piracetam, ashwagandha and rhodiola. Due to the way I introduced each one, I can isolate their individual effects.

#8 health_nutty

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Posted 04 July 2010 - 04:45 AM

Very interesting, please keep us posted. Let us know what your whole "stack" is.

#9 Wurzel Bagman

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Posted 04 July 2010 - 05:47 AM

Although i've tried many nootropics (aniracetam, pramiracetam, bacopa, rhodiola, various combo formulas from iherb: Natrol's brainSpeed, Now's True Focus, and Jarrow's Neuro Optimizer) my daily "stack" seems to have ended up being vitamin b-100 complex, cal-mag, vitamin C, omega 3, rhodiola, lecithin, siberian ginseng and of course now the copious amounts of piracetam.

From my previous experiences of mega dosing i see little need to add anything more to the mix. You feel so full of life and being that nothing else feels necessary. Just enjoying anything and everything in the extreme piracetam state is enough.

When im feeling adventurous i may try some of the formulas i got on iherb with the large piracetam doses.

#10 stablemind

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Posted 04 July 2010 - 10:06 AM

Although i've tried many nootropics (aniracetam, pramiracetam, bacopa, rhodiola, various combo formulas from iherb: Natrol's brainSpeed, Now's True Focus, and Jarrow's Neuro Optimizer) my daily "stack" seems to have ended up being vitamin b-100 complex, cal-mag, vitamin C, omega 3, rhodiola, lecithin, siberian ginseng and of course now the copious amounts of piracetam.

From my previous experiences of mega dosing i see little need to add anything more to the mix. You feel so full of life and being that nothing else feels necessary. Just enjoying anything and everything in the extreme piracetam state is enough.

When im feeling adventurous i may try some of the formulas i got on iherb with the large piracetam doses.



I have never heard of anyone being able to maintain this type of hypo-manic state without building tolerance, having the rebound effect or becoming manic (cough *isochroma* cough).

You may want to reevaluate your decision to use such an extreme dose, but I'm quite curious to know the result so keep up the great work with the detailed posts.

I'm using piracetam at rather low doses, 800-1600mg and I've noticed a very pronounced effect on character as well. I have a lot more confidence, and feel like I can engage myself much more in activities, although the memory issues are still present from BPII/ADHD. I may experiment with higher dosages in the future although I'm quite worried about withdrawal effects.

#11 kassem23

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Posted 04 July 2010 - 10:39 AM

Does anyone have any experiences of mega dosing to share? Are there any major risks associated with it? (i went about a month on my initial mega dose spree) To people that claim the stuff doesn't do much, have you tried 12gram doses?


Anything that is - by it's very nature hypomanic is unsustainable and I believe should be avoided. Isochroma was a great example of what hypomanic/manic doses can do to you. The change you and suddenly it's unsustainable and you collapse. Unless you want to go into full blown mania I suggest keeping the dosages low. People with bipolar disorder might also be at higher risk.

I wish you the best of luck.

#12 stablemind

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Posted 04 July 2010 - 11:07 AM

Does anyone have any experiences of mega dosing to share? Are there any major risks associated with it? (i went about a month on my initial mega dose spree) To people that claim the stuff doesn't do much, have you tried 12gram doses?


Anything that is - by it's very nature hypomanic is unsustainable and I believe should be avoided. Isochroma was a great example of what hypomanic/manic doses can do to you. The change you and suddenly it's unsustainable and you collapse. Unless you want to go into full blown mania I suggest keeping the dosages low. People with bipolar disorder might also be at higher risk.

I wish you the best of luck.


Hey,

I've read some of your posts and I've noticed increased verbal fluidity/confidence as well but I'm still having issues with learning new things quickly, and I don't really notice a change in spacial memory. An example is that I'm able to express myself much more and I'm a lot more assertive, yet I cant even learn black jack and can't recognize the cards nearly as fast as others. Like Ace is 1 or 11, queen is 10, etc.. have you noticed this as well?

#13 Wurzel Bagman

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Posted 04 July 2010 - 01:04 PM

Does anyone have any experiences of mega dosing to share? Are there any major risks associated with it? (i went about a month on my initial mega dose spree) To people that claim the stuff doesn't do much, have you tried 12gram doses?


Anything that is - by it's very nature hypomanic is unsustainable and I believe should be avoided. Isochroma was a great example of what hypomanic/manic doses can do to you. The change you and suddenly it's unsustainable and you collapse. Unless you want to go into full blown mania I suggest keeping the dosages low. People with bipolar disorder might also be at higher risk.

I wish you the best of luck.


Hey,

I've read some of your posts and I've noticed increased verbal fluidity/confidence as well but I'm still having issues with learning new things quickly, and I don't really notice a change in spacial memory. An example is that I'm able to express myself much more and I'm a lot more assertive, yet I cant even learn black jack and can't recognize the cards nearly as fast as others. Like Ace is 1 or 11, queen is 10, etc.. have you noticed this as well?


After doing some research on hypomania i would have to agree that is what large doses of piracetam does. From my initial large dose stint I maintained a hypomania state for the duration of it. I didn't go maniac or have any terrible experience, crash or withdrawal symptoms at the end. Thanks for the concern Kassem! I will make it a routine of regularly stepping back and evaluating my situation and will cut down on the doses if i begin to not sleep enough or start expressing unsavoury behaviour.

I might not be informed of the whole Isochroma story but from what i read of his posts, the guy was a poetic literary master. His metaphors and creative writing abilities were very impressive. It is true that he was a bit odd (talking about becoming god and crushing skulls in his dreams and what not) but if you do some simple googling of his username you'll find that he's active on a few anime forums... a culture where characters becoming immensely powerful and God-like is very much a norm. I speculate that Isochroma likely just got full of himself from all the attention, then continued posting for his own enjoyment and got carried away. He likely enjoyed reading people's reactions to them and took them a little further each post. It was probably a hobby for him; an outlet with feedback for his creative side.

A short time later he became well known as an insane maniac that ate piracetam by the bucketload. This likely hurt his feelings. He probably did a reality check and decided he didn't like his situation here and wanted his posts removed. I imagine Isochroma is still an active member on these forums taking on a completely different persona and likely still taking piracetam. (Isochroma if you're around I would love to chat with you sometime so PM me :) )

Stablemind, I have always been a relatively quick learner and find my only downfall to be when im in a negative mood and choose not to learn. Other than telling you to have a positive mindset when attempting to learn I can't really help you with your blackjack troubles. I don't have that challenge in my life.

I will be sleeping for a bit but will keep you guys posted when i have my next 12g dose!

Edited by ptamaddict, 04 July 2010 - 01:11 PM.


#14 kassem23

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Posted 04 July 2010 - 03:05 PM

After doing some research on hypomania i would have to agree that is what large doses of piracetam does. From my initial large dose stint I maintained a hypomania state for the duration of it. I didn't go maniac or have any terrible experience, crash or withdrawal symptoms at the end. Thanks for the concern Kassem! I will make it a routine of regularly stepping back and evaluating my situation and will cut down on the doses if i begin to not sleep enough or start expressing unsavoury behaviour.

I might not be informed of the whole Isochroma story but from what i read of his posts, the guy was a poetic literary master. His metaphors and creative writing abilities were very impressive. It is true that he was a bit odd (talking about becoming god and crushing skulls in his dreams and what not) but if you do some simple googling of his username you'll find that he's active on a few anime forums... a culture where characters becoming immensely powerful and God-like is very much a norm. I speculate that Isochroma likely just got full of himself from all the attention, then continued posting for his own enjoyment and got carried away. He likely enjoyed reading people's reactions to them and took them a little further each post. It was probably a hobby for him; an outlet with feedback for his creative side.

A short time later he became well known as an insane maniac that ate piracetam by the bucketload. This likely hurt his feelings. He probably did a reality check and decided he didn't like his situation here and wanted his posts removed. I imagine Isochroma is still an active member on these forums taking on a completely different persona and likely still taking piracetam. (Isochroma if you're around I would love to chat with you sometime so PM me :) )

Stablemind, I have always been a relatively quick learner and find my only downfall to be when im in a negative mood and choose not to learn. Other than telling you to have a positive mindset when attempting to learn I can't really help you with your blackjack troubles. I don't have that challenge in my life.

I will be sleeping for a bit but will keep you guys posted when i have my next 12g dose!


Isochroma is on M&M now, if anybody is looking for him. http://www.mindandmu...showtopic=42421

Edited by chrono, 26 August 2010 - 04:13 PM.
trimmed quote


#15 unregistered_user

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Posted 04 July 2010 - 07:44 PM

I took what I roughly measured out as a 10g dose this morning and then came home at 3:30pm (about 15 minutes ago) and took a carefully measured 12g dose.

I felt tired and sluggish from 8AM (when I first dosed) until I arrived home just now. At first colors were enhanced, which is one of the common effects Piracetam has, but then I just felt flat personality wise and extremely tired. We'll see how this recent 12g dose makes me feel.

-SRI

#16 unregistered_user

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Posted 05 July 2010 - 12:32 AM

Same results. Nocked me out in 20 minutes and I slept for 4 hours. I guess the larger doses just aren't for me.

#17 medievil

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Posted 05 July 2010 - 12:36 AM

Same results. Nocked me out in 20 minutes and I slept for 4 hours. I guess the larger doses just aren't for me.

It takes a few days to kick in mate, the OP also reported being sleepy.

For a few days i didn't notice much difference aside from clarity of vision and feeling very sleepy at times. Then I started to get what seemed like limitless energy. I felt very much alive and full of life. My eyes gleamed, shiny and bright as continued taking large doses of this stuff.



#18 stablemind

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Posted 05 July 2010 - 12:57 AM

I was tired when I first started taking piracetam as well and after a few days the effects kicked in. It could be the ACh receptors are still upregulating and your body is trying to replenish its supply to get the cycle going again.. I would keep your egg intake high, and your carbs high as well.

#19 chrono

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Posted 05 July 2010 - 01:51 AM

The bell-shaped dosage response curve isn't "proven," by any means. It may not hold true for everyone, or be true at all. Personally, after a couple months of careful experimentation, I found that doses in the 800-1200mg range worked better for me than 2g+.

The improvements in cognition reported with megadoses don't sound substantially different than what I get from 800mg. What is different are its effects on mood. That's a perfectly valid target for pharmaceutical intervention, but potentially interferes with judgement about cognitive effects. For instance, being manic enough to do things you normally wouldn't doesn't necessarily mean quality of thinking has improved.

And be aware that you're experimenting at something like 10x the dosage used for most studies in humans. Just because it's considered non-toxic does not mean that it can't screw up your neurotransmitter levels, or as previously noted, cause something akin to mania. And I'd be much more worried about sustainability. But for all I know, it may be fine, and may be worth experimenting with.


Isochroma also showed up on BrainMeta this week, with a perhaps-selective summary of his piracetam use. Wouldn't be surprised if he showed up here as well...maybe with a different name. ;)
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#20 unregistered_user

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Posted 05 July 2010 - 01:57 AM

Thanks medievil, stablemind and chrono (I always vote you up man, your posts are incredibly helpful). I'll stick with the 12g dose for the next few days and see if anything changes.
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#21 unregistered_user

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Posted 05 July 2010 - 02:46 AM

I was tired when I first started taking piracetam as well and after a few days the effects kicked in. It could be the ACh receptors are still upregulating and your body is trying to replenish its supply to get the cycle going again.. I would keep your egg intake high, and your carbs high as well.


Well then let's upregulate those babies! :-P

I just took another 7g. So far that's a total of roughly 29g today I think. I started with an approximate 10g this morning, a carefully measured 12g at around 3:30pm and now (10:45PM) another 7g.

#22 chrono

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Posted 05 July 2010 - 03:00 AM

Incredibly helpful!? That's the nicest thing anyone's said about me all week! Thanks ;)

I should probably have also said that piracetam's depletion of acetylcholine has been demonstrated in rats. Unless something weird happens at much higher dosages, I expect this kind of experimentation would benefit from larger doses of choline precursors.

I'll be interested to hear your observations about higher dosages.

Edited by chrono, 05 July 2010 - 03:01 AM.


#23 unregistered_user

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Posted 05 July 2010 - 07:36 PM

I've been taking choline bitartrate along with my piracetam doses for the past 6-8 weeks because I thought it would produce a synergy or at least prevent the tension headaches. I don't know...maybe it does...but I've taken several megadoses of 10 and 12 grams WITHOUT the choline bitartrate and haven't had any headaches or felt any differently as a result so far as I can discern.

This is day 2 of megadosing. I'll keep it up for 7-10 days and see if it brings about any god-like transformation (I say that in jest) :P

I'm just looking for pronounced clarity of mind and hopefully some euphoria. My experience with drugs and supplements is very limited so I'm hoping for something I can notice without a doubt. So far, all the effects have been rather subtle.

#24 outsider

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Posted 06 July 2010 - 08:22 AM

The biggest sigle dose I have taken was 6 gm and I enjoyed it. At that time I was taking two doses of 3 gm throughout the day. I would have taken 12 gm easily but was affraid of the bell shaped curve everyone was talking about. At that time I got inspired by Pete Hitesman's blog (Owner of Relentless Improvement) who said that you should get plenty of piracetam.

But right now honestly I have too much fun with my herbs to consider taking risk with a synthetic substance.

Maybe I'll try it for fun in the future, it's nice to know.

Edited by outsider, 06 July 2010 - 08:23 AM.


#25 Jurence

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Posted 06 July 2010 - 01:35 PM

took 50g last night, 40g this morning and have 40g for lunch. I feel very O_O

#26 health_nutty

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Posted 06 July 2010 - 04:13 PM

took 50g last night, 40g this morning and have 40g for lunch. I feel very O_O


I hope you are kidding.

#27 unregistered_user

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Posted 06 July 2010 - 05:03 PM

The biggest sigle dose I have taken was 6 gm and I enjoyed it. At that time I was taking two doses of 3 gm throughout the day. I would have taken 12 gm easily but was affraid of the bell shaped curve everyone was talking about. At that time I got inspired by Pete Hitesman's blog (Owner of Relentless Improvement) who said that you should get plenty of piracetam.

But right now honestly I have too much fun with my herbs to consider taking risk with a synthetic substance.

Maybe I'll try it for fun in the future, it's nice to know.


Which herbs are you having fun with? :)

#28 Animal

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Posted 06 July 2010 - 05:15 PM

Don't expect euphoria from piracetam, it's impractical to chase euphoria anyway since it is transitory by it's very nature. A highly ignorant way to treat mood disturbances.

If anything alters your mood in this regime of piracetam abuse then it'll be a hypomanic episode, which is far from healthy neurologically and once again transient.

LOL, Isochroma has probably just been released from the psychiatric unit, if he decides to continue his absurd consumption of piracetam I expect he'll be giving them another visit soon. Mania has a way of reinforcing the desire for not only that state of mind but also abuse of the substance which may have caused it. The delusions tend to linger for months, maintaining the belief that you are right and everyone else is wrong.
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#29 unregistered_user

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Posted 06 July 2010 - 05:44 PM

Thanks Animal. That makes sense.

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#30 Animal

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Posted 06 July 2010 - 06:19 PM

Thanks Animal. That makes sense.


I was a bit aggressive in my previous post, but it's only because I see so many people on these forums attempting to get high through abuse of nootropics or ADD medication.

Now I know you have mood disturbances, and are not necessarily trying to get a high, but more likely alleviate what feels like a ubiquitous low mood/lack of pleasure, so I can understand the motivation behind that. It's just that there are far more appropriate mood enhancers with a sustained effect that would be healthier psychologically and physiologically for you. Any form of mania is negative psychologically since it encourages mild delusions of grandeur and lust for the state of mind.

I've seen high piracetam doses liked with hypomania numerous times and typically on the come down the user has a form of temporary dysthymia which leads them to try ridiculous mega-dosing in an attempt to reclaim the buzz. Euphoria is an abnormal state and inherently has a reinforcing effect, people do not get true euphoria naturally unless some substance is involved be it holistic or not. Unless they are one of the rare individuals who has brain chemistry which tends to precipitate an enhanced mood state, the lucky bastards. Although these individuals do tend to be less productive then average because they see less reason to pursue rewarding activities.

If you are looking for more sustainable mood enhancers then make a thread about it and I'll be happy to recommend some to you.
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