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New Achilles Heel In Cancer Cells Discovered By Scientists

cancer

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#1 MrHappy

MrHappy
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Posted 06 December 2011 - 12:00 AM

http://www.doctortip...scientists.html

During the study researchers removed a protein name FAK from cancerous cells grown in the lab and mice with cancer. The FAK protein combined with another protein named SRC work together and promote tumor dissemination and development. Removing the FAK protein, leaves the SRC protein unpaired which alone, in high amounts is very toxic for cancerous cells leading therefore to apoptosis. The only problem is researchers also found that, cancerous cells can adapt and eliminate the unbinded SRC protein and avoid death.
Scientists discovered that cancerous cell can actually digest the excess SRC protein (autophagy) by including them in vacuoles (organelle major with a role in maintaining a balance between the production and degradation, of certain substances and cellular structures). It was not previously know that cancerous cell can actually dispose SRC protein using this mechanism.





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