I thought of a new longevity theory
It is published that immunizing rabbits against cholesterol keeps them from getting atherosclerosis. http://www.ncbi.nlm....pubmed/18036243 http://www.ncbi.nlm....icles/PMC42712/
Thus, just as vaccines sometimes fade, as well as immunosensitivities accumulate, it is possible young persons have different age predictable immunoreactivities to a variety of things.
Using frozen embryos you can make clonal mice of different ages, just thaw n implant the young embryo a few years later to get a young clone. Then to see if the different immunosensitivities affect aging you give the elderly mouse young clone immunoglobins to reimage a young immune system. Then you see if it gets weller as well as lives longer.
Then do a chromatography of the difference between old n young to locate the things they are differently immunogenic towards that reduce aging as well as create longevity.
Theoretically older people may have created immune responses to naturally occuring longevity chemicals as well as cytokines, reducing their amount. similarly younger persons may have an active immune response to things that are naughty that wears off with age.
Noting the rabbit cholesterol immunization longevity effect, if a middle aged person has immune response that mops up cytokines that say "tell some other part of the body to remove cholesterol" then cholesterol might go up, causing gunkification. similarly a young person might have a fresher immune response to cytokines that say "make cholesterol" where mopping up reduces the amount of cholesterol made. I am describing cytokines here as immunosensitization to ultratrace chemicals would make a larger difference.
Lipitor makes cholesterol people live longer, its published that physioimmunity to cholesterol causes less heart disease, so the thing is to go farther than that one thing to describe the difference between a teen or 20s list of protein as well as peptide immunoreactivities n a much older persons reactivities to find the human versions. Then reImage the longevity version of the immune system.
Note this is different than immunosensitivity to ones own tissue, this is immunosensitivity to plasma proteins or peptides rather than cytosurfaces.
Edited by treonsverdery, 04 May 2012 - 01:06 AM.
