Quote: "Stablon effect should be noticeable on the first day". Isn't that very personal speech brought forward as if it was widely shared ?
Let me quote just one other speech,the one by Servier lab (creator of the product) representatives: "An absolute minimum of three weeks is necessary before any first benefit can be expected". Prescriptors information here relies heavily on the pharmaceutical industry reps; And that is what they are taught to say in their seminars. Has anyone here personnaly heard differently from a Servier rep ?
For that matter, has anyone "here" (Longecity or Monaco?) ever spoken with a Servier rep at all?
I first took it in the evening and noticed the effect the next morning. I felt more positive, with more mental engergy, than I had in months or years. Although I attribute that state to commencing with Stablon the evening before, note that the half-life had long expired between taking the pill and the feeling I remember on wake-up. I have not felt that intensity of well-being since then, and the feelings of well-being seem to be much more closely associated with the timing of administration of the compound. That is, I can usually feel when the pill is wearing off and it is time for the next. In fact, when I can no longer so distinguish, I will conclude that tianeptine is no longer working for me and I will stop using it for awhile before trying again. Note that I have been using this compound for over a year now with excellent results. In contrast, after about a week of tianeptine, I stopped the antidepressant cocktail of sertraline, provigil, and bupropion XL which I had been on for years. I stopped it cold turkey, with no tapering whatsoever, and felt no effect from the cessation whatsoever. That tells me that the cocktail was not working.
Of all the many personal stories that I have read about people's first experience with tianeptine, most seem to indicate an onset of effect within hours to a very few days. Not sure that I have ever read of anyone for whom it has taken as long as weeks. On the other hand, keep in mind that tianeptine is experimental in some parts of the world, including USA. How many such experimental users will continue with a compound every few hour for weeks without feeling any effect? Not many, I suspect. Thus, people for whom tianeptine might take effect after weeks are probably grossly under-represented in the experimental crowd. Most will simply declare that the drug does not work for them after a few days.
A possible take-away from this regarding psych meds (whose development is in the stone age due to the complexity of the problem) is that it may be easier to know if a compound with a subtle effect works for an individual through cessation than through initiation. If true, that could be a reason for advocating a multi-week trial. Such a process virtually guarantees that initiation has occurred so that cessation can be tested.
Edited by Bruce6815, 26 March 2013 - 07:01 PM.
LongeCity
