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Acetyl-l-carnitine and hypothyroid supplementation (hashimoto's thyroiditis)

thyroid alcar acetyl-l-carnitine hypothyroid levothyroxine synthroid carnitine

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#1 Mindfix

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Posted 17 June 2012 - 07:48 PM


Hello, this is my first post , but i have been lurking quite sometime ,actually have spent many hours learning in your forums!

(i suppose this is the right place to post this question)

I am a 25 male student and have been experimenting and supplementing with some nootropics for almost a year, my primary source of information being longecity and the internet.
I am diagnosed with hashimoto's thyroiditis and supplementing T4 every day first thing in the morning (half an hour before breakfast or my other supplements, a rule which i dont keep sometimes)
I also beleive i have ADHD too ,but i am not diagnosed for that, and never went to a doctor to diagnose me anyways

I have used:
-piracetam (most usual dosages : .6g/5hrs 3 times a day , and sometimes 1.2g in the morning or middle dose or both) have used it for 1-3 month periods leaving 2-3 months breaks between)

-aniracetam( have used for one month in combination with piracetam 350mg dosages 2-3 times a day , and sporadicaly every now and then combining with pir) the anxiolytic effect is nice but seems that it makes me slack , i have noticed that my vision is greatly enhanced with ani, which also happens with pir but to a lower degree. and oxi is probably the next racetam i am going to try , i think i will like the speedy effect people report

-alpha gpc /lecithin as choline sources (~1g alpha gpc divided in two daily doses of .5g each , 2g lecithin also in two doses)


(other supplements are : fish oil, gingko ,ginseng, magnesium, selenium, melatonin,alpha lipoic acid, c,e vitamin, b complexes and multivitamins mainly) these are taken usually far away from T4 esp. magnesium/selenium and multies

I dont take all these together, all though some times i have

Now, I have also tried acetyl l carnitine, and really liked the results , especially the energy and mood lift, but have not extensively used it because I read on the internet that it somehow stops or lowers the absorption of thyroid T4 supplements (e.g synthroid/levothyroxine /thyrohormone etc )

Do you think that taking ALCAR some time after T4 (4-6 hours) would minimize this effect/ would i have all the T4 pill properly absorbed by then ? I was thinking to take T4 1-2 hrs after i have gone to bed, so that when i wake up i can take alcar and everything else and eat breakfast without having to wait for 30-60 mins as i am advised to for better T4 absorption

What is the half-life of alcar , and after how much time from the last dose can i dose T4 efficiently?

Maybe those two questions are wrong because alcar keeps on blocking T4/T3 no matter when i take it, but for all the time that it is in my body? (it has a cumulutive effect as i read) and generally all thyroid hormones , pushing the thyroid to work more , which is not good at all in my case?(i am supplementing with T4,if i understand correctly so that my thyroid doesnt have to make it, just convert it to T3) Or maybe it also does that AND inhibitis the absorption of the pill when i take it?

Either way maybe upping the dose of T4 a bit would solve the problem? (off course i would ask a doctor first, or take thyroid blood tests often to monitor my antibodies / Tsh / T3/ T4 etc for changes)

I really liked alcar and really want to find a way to use it safely, plus it seems that it helps in so many aspects over time

maybe doses of .5g twice or three times a day(which i intend of using) are not that big and not causing that big of a problem?

Anyways, many questions already asked ,thanks in advance for your replies !

Edit: some links:

http://www.mendeley....rmone-action-1/
http://www.mythyroid.com/vitamins.html
http://www.prohealth....cfm?id=1153181

Edited by Mindfix, 17 June 2012 - 08:06 PM.

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#2 bernard

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Posted 25 June 2012 - 09:28 PM

Keep in mind that I've heard Piracetam could interfere with Thyroid medication. I'm no expert but you should Google it.
Check this out:
http://www.ncbi.nlm..../pubmed/7403353
http://www.longecity...hypothyroidism/

In fact "potentiating thyroid medication" is one of the known possible side effects listed in the piracetam brochure.

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#3 Mindfix

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Posted 28 June 2012 - 11:23 AM

Hi there! thanks for your reply, piracetam and thyroid medication dont seem to interfere with each other , i searched quite a bit before trying it , also the thread that you linked does seem to say the same.
but anyways i take any supplement , most times after 2 hours of having taken my thyroid pill

and if it potentiated my thyroid medication i dont think that it would be bad, but only good .

but i am really concerned about alcar, it seems to be proven that it somehow interferes with how available thyroid hormones are in the cells.

Anyone? (someone should be hypothyroid in here! and alcar is not a rare supplement , at least in this forum!)





Also tagged with one or more of these keywords: thyroid, alcar, acetyl-l-carnitine, hypothyroid, levothyroxine, synthroid, carnitine

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