LONGECITY

I think the meythlation theory and mood disorders/mental health still has alot of tweaking that needs to be done for understanding.


For example, by all observation I would be considered an undermeythlator, however I find niacinimide seems to bring relief to me even though niacinimide is supposed to be bad for undermeythlators.

Somesuggest niacinimide spares trytophan, it also raises blood glucose. Some theorize higher blood glucose may raise serotonin. The theory is serotonin reduces hunger, and if ones blood glucose is higher they would not want to eat as much to raise it.

On the other hand it is quite common for people who have anxiety to experience hypoglycemia, they often get relief from eating carbs, that may explain why in offices people always bring in sugary treats.

B6 tends to lower blood glucose, it is a glycation inhibitor. This for some may make anxiety worse, even though B6 is believed to be good for under meythlators and those with anxiety.

I do agree balane is key and it can be personal.

I have personally find too much B6 gets me panicky, too much b12 gets me lethargic, too much niacinimide gives me a runny nose, too much folic acid also gives me anxiety. Too much choline gives me a headache.

I respond well to inositol outside of it gives me some stomach cramps and loose stools. The only B vitamin that so far has not given me any sides is B5, unfortunately it was the last one I tried because you don't hear about people needing it too often.

how do i check my histamine levels ??

Blood tests.

Balance is the key, and it is generally best to obtain one's b vitamins from a wide set of sources rather than in a shot, a pill, or a cap.

High-dose (300 mg) niacinamide causes oxidative stress and impaired glucose tolerance. This dosage isn't much different than regular B complex dosages. Google post by Paul Jaminet.

That's quite strange. I actually love Vitamin B-3 (Niacin) I take lots of it daily.. I'm noticing vascularity as the cosmetic effects of it and I love that!

^ this is vitamin b the negatives thread. dont see why you would post here praising them which is oposite idea.

Niacin is said to help in cardivascular health yes, but in combination with Inositol 50/50 and there are many reports out there, the high dose needed to achieve this causes liver problems.

so there you. negative about vitamin b3

http://www.livestron...100-milligrams/

that url only discusses dangers of pyridoxine and niacin. i wonder why they didnt put dangers of other high doses of Bs

I heard somewhere that megadoses with the activated forms do not have the negative effects of the inactive forms (for example, P5P vs. pyridoxone HCl). Can anyone confirm if this is true?

One example of this specifically with B6 can be found near the end of this document: http://www.thorne.co...text/6/1/87.pdf in the section called "Safety, Toxicity, and Side Effects."

While I'm on the subject, is it true that you only need the active forms if your body lacks the ability to process the regular kind? In other words, is pyridoxone HCl just fine for you unless you specifically know your body doesn't use it correctly, in which case you should use P5P?
Edited by ironfistx, 04 January 2013 - 01:46 AM.

I get headaches from folate doses over 400mcg and sometimes with 400mcg when my diet is rich in folate. Did you get any of that with your mood swings? I think in some cases the receptors can clog and prevent b12 from being absorbed... there is a medical condition for this but I can't remember what it's called.

If I eat a food high in folate, I have no problems at any dose. If I take a folate supplement, I have really horrible depressive mood swings where I become almost suicidal, which is strange because everyone says it's supposed to make you feel better. I notice that with a few B vitamins actually and I dont get the effect otherwise.

Benfotiamine is antiglycating (sp?) Could it be that freeing up AGEs causes them to get stuck elsewhere?

Benfotiamine is antiglycating (sp?) Could it be that freeing up AGEs causes them to get stuck elsewhere?

interesting theory. did you gather this from anywhere else or is it personal ? it is kind of disturbing to think about :s

The anti-AGE info? yeah I read it somewhere and there was a comparison between it and other esoteric B vitamin forms.

The idea of them getting stuck elsewhere? Well it's just a big messy system...

Benfotiamine is antiglycating (sp?) Could it be that freeing up AGEs causes them to get stuck elsewhere?

interesting theory. did you gather this from anywhere else or is it personal ? it is kind of disturbing to think about :s

cryonicsculture, do you know how this happens and if they do get stuck elsewhere, where and how

just postulating