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NSI-189

nsi-189

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#211 MetaMind

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Posted 17 April 2013 - 11:18 AM

Good Job ScienceGuy... :D
but this is allmost twice as much as "sunshinechem" has offered.
Is this "EUROPEAN CUSTOM SYNTHESIS LAB" really that more reputable?

Also you mentioned the price 54,50$ per gram is for a 200g order quantity, so what is it for 100g?

Edited by MetaMind, 17 April 2013 - 11:21 AM.

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#212 z85

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Posted 17 April 2013 - 11:30 AM

Isn't $54 cheaper than the $170? I suck at math but the other breakdown was only for a 100 grams for 29/30 people averaged out to 170 a person. page 3 not sure of the post number.

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#213 MetaMind

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Posted 17 April 2013 - 11:31 AM

btw speaking of custom synthesize companys...
I found a list with dozens of Labs that are offering this service:

Check this out:
http://www.rdchemica...esis-companies/


@z85
well Sunshinefrost said the the company sunshinechem could do it for 2580$ for 100g, but who knows if they reliable or not.

Edited by MetaMind, 17 April 2013 - 11:34 AM.


#214 Psionic

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Posted 17 April 2013 - 11:37 AM

I would go for it, ScienceGuy. 2G for each is enough for 1 month trial..

It would be good to get in touch with somebody from current 1b trial on NSI-189 to research even more details/informations

#215 Werper

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Posted 17 April 2013 - 12:07 PM

Count me in.

#216 Izan

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Posted 17 April 2013 - 01:27 PM

No CAS? Isn't that a pretty big obstacle?


An obstacle, yes; but not insurmountable ;)

OK everyone, I now have all the necessary information from the EUROPEAN CUSTOM SYNTHESIS LAB :)

Details as follows:

MINIMUM PURITY: 99.5%

LEAD TIME: 4-5 Weeks

PRICE: US$ 54.50 / GRAM (for 200g order quantity)

Hence, for comparison purposes the price works out to be US$5,450 for 100 GRAMS

To be honest this is about what I expected it to cost from a reputable manufacturer ;)

N.B. I should add that these guys already have the SYNTHESIS ROUTE worked out, and hence do not need CAS

Thoughts? :)

BTW I am not adding anything whatsoever onto this cost and would intend to post online a copy of the PURCHASE INVOICE (as I did with COLURACETAM) ;)

nice work, thank you. but ask them if they could lower the price to 40 dollars for 1 gram. 54.50 is too much. what about prices for idra-21 and dihexa?

#217 sunshinefrost

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Posted 17 April 2013 - 01:34 PM

i've got a few replies,

sunshine chem:
2580 for 100grams

Tractus
2625 for 10 g // 4265 for 100g

Angene
2635 for 10g // 4359 for 100g

letopharm
1500 for 10g // 3500 for 100g

#218 meatsauce

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Posted 17 April 2013 - 01:36 PM

On the pay it square website I only see a regester new organizer account. Is this the one we are supposed to sign up for?

#219 sunshinefrost

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Posted 17 April 2013 - 01:39 PM

On the pay it square website I only see a regester new organizer account. Is this the one we are supposed to sign up for?


no i would be the organiser... is there any other options ? i suspect you would need to search a group before being able to pay

#220 meatsauce

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Posted 17 April 2013 - 02:07 PM

On the pay it square website I only see a regester new organizer account. Is this the one we are supposed to sign up for?


no i would be the organiser... is there any other options ? i suspect you would need to search a group before being able to pay


I didn't see one. So I wait until everything is good to go then find the group? Do I need to upgrade my Paypal as well?

Edited by meatsauce, 17 April 2013 - 02:09 PM.

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#221 NeurogenesisFactor

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Posted 17 April 2013 - 02:51 PM

Add me to the group buy please, I'm a former ImmInst member and after researching this potential nootropic, I am very interested in buying in.

#222 sunshinefrost

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Posted 17 April 2013 - 02:52 PM

On the pay it square website I only see a regester new organizer account. Is this the one we are supposed to sign up for?


no i would be the organiser... is there any other options ? i suspect you would need to search a group before being able to pay


I didn't see one. So I wait until everything is good to go then find the group? Do I need to upgrade my Paypal as well?


yes wait untill my account is linked and the group is created. I'll let you know. And no you don't need to upgrade

#223 daouda

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Posted 17 April 2013 - 03:12 PM

I personnaly think a minimum of 2.5g per person would be better for a trial (would allow for 40mgx2 for 30 days - the clinical trial (also a pharmacokinetics study) doses are 40mg once, twice ot thrice per day http://clinicaltrial...how/NCT01520649 ).
I first thought about getting 6g to allow for 2 months at 100mg/day, but it probably is much wiser to assess the thing for a shorter period first and at more conservative doseage.
100g is enough for 40 ppl to get 2.5g each

So I think the ideal thing would be to get 40ppl to buy 100g for this first group buy?
Who's with me?

Edited by daouda, 17 April 2013 - 03:17 PM.


#224 NeurogenesisFactor

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Posted 17 April 2013 - 03:17 PM

I am in, naturally, but I would warn against such a high dose for young healthy adults. It's unclear there is significant scope for healthy hippocampus growth. The same 2.5g could be applied at a lower dose for these individuals. If you're over 50, you might find it worthwhile to ramp up though.

Edited by NeurogenesisFactor, 17 April 2013 - 03:48 PM.


#225 daouda

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Posted 17 April 2013 - 03:21 PM

Well if ppl want to try a lower dose they could still do it, personnally my brain is definitely not healthy (but not exactly "depressed", so I dont know wether the hippocampus is the right target for me) and will be trying this stuff for therapeutic purposes as a desperate move to improve my condition, so choosing the median dosage of the clinical trial seems rather sensible and reasonable. Patients in the study are aged 18 to 60 y.o., not healthy (depression patients).

Edited by daouda, 17 April 2013 - 03:23 PM.


#226 Reformed-Redan

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Posted 17 April 2013 - 04:01 PM

i've got a few replies,

sunshine chem:
2580 for 100grams

Tractus
2625 for 10 g // 4265 for 100g

Angene
2635 for 10g // 4359 for 100g

letopharm
1500 for 10g // 3500 for 100g

We need to figure out if sunshine-chem is legit. 10g sample order from them explaining that it is necessary to verify that they can actually make the substance and then do a full third party analysis on the compound.

#227 sunshinefrost

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Posted 17 April 2013 - 04:08 PM

i've got a few replies,

sunshine chem:
2580 for 100grams

Tractus
2625 for 10 g // 4265 for 100g

Angene
2635 for 10g // 4359 for 100g

letopharm
1500 for 10g // 3500 for 100g

We need to figure out if sunshine-chem is legit. 10g sample order from them explaining that it is necessary to verify that they can actually make the substance and then do a full third party analysis on the compound.


How do you find out if it's legit ? Care to try and find reputation websites for labs ?

#228 daouda

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Posted 17 April 2013 - 04:11 PM

I must say I'm getting a strong "too good to be true" vibe from sunshinechem...

Sunshinefrost (and others), what do you think of my suggestion to aim for 2.5g per person (with my rationale explained above)? (meaning 100g for 40ppl)

Edited by daouda, 17 April 2013 - 04:15 PM.


#229 sunshinefrost

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Posted 17 April 2013 - 04:11 PM

No CAS? Isn't that a pretty big obstacle?


An obstacle, yes; but not insurmountable ;)

OK everyone, I now have all the necessary information from the EUROPEAN CUSTOM SYNTHESIS LAB :)

Details as follows:

MINIMUM PURITY: 99.5%

LEAD TIME: 4-5 Weeks

PRICE: US$ 54.50 / GRAM (for 200g order quantity)

Hence, for comparison purposes the price works out to be US$5,450 for 100 GRAMS

To be honest this is about what I expected it to cost from a reputable manufacturer ;)

N.B. I should add that these guys already have the SYNTHESIS ROUTE worked out, and hence do not need CAS

Thoughts? :)

BTW I am not adding anything whatsoever onto this cost and would intend to post online a copy of the PURCHASE INVOICE (as I did with COLURACETAM) ;)


if you say they are trustworthy I don't really mind that it's more expensive.

what's the name of that lab ? have you ever dealt with them and do you think you could get them to split the shipment in 3 different locations ?

#230 DamnedOwl

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Posted 17 April 2013 - 04:12 PM

I must say I'm getting a strong "too good to be true" vibe from sunshinechem...


:-D I was just about to use the same phrase.

#231 NeurogenesisFactor

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Posted 17 April 2013 - 04:15 PM

Review sunshine chem's reputation if it's listed on an Alibaba exchange or similar outlet.

These drugs are not extremely expensive to synthesize, you're paying a premium for a low demand item with limited competition and scale discounts to be had through reseller bulk purchasers.
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#232 Q did it!

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Posted 17 April 2013 - 04:16 PM

No CAS? Isn't that a pretty big obstacle?


An obstacle, yes; but not insurmountable ;)

OK everyone, I now have all the necessary information from the EUROPEAN CUSTOM SYNTHESIS LAB :)

Details as follows:

MINIMUM PURITY: 99.5%

LEAD TIME: 4-5 Weeks

PRICE: US$ 54.50 / GRAM (for 200g order quantity)

Hence, for comparison purposes the price works out to be US$5,450 for 100 GRAMS

To be honest this is about what I expected it to cost from a reputable manufacturer ;)

N.B. I should add that these guys already have the SYNTHESIS ROUTE worked out, and hence do not need CAS

Thoughts? :)

BTW I am not adding anything whatsoever onto this cost and would intend to post online a copy of the PURCHASE INVOICE (as I did with COLURACETAM) ;)


Than I say we go with ScianceGuys supplier. 2.5 grams per participants that equates to forty participants at $136.25 plus add $5- $10 for shipping and repackaging a for a total of 141.25 or 146.25 I say just round it to $145.00 total cost for 2.5 grams.

#233 daouda

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Posted 17 April 2013 - 04:19 PM

That price is for a total bulk order of 200g, not 100g...

#234 daouda

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Posted 17 April 2013 - 04:24 PM

No CAS? Isn't that a pretty big obstacle?


An obstacle, yes; but not insurmountable ;)

OK everyone, I now have all the necessary information from the EUROPEAN CUSTOM SYNTHESIS LAB :)

Details as follows:

MINIMUM PURITY: 99.5%

LEAD TIME: 4-5 Weeks

PRICE: US$ 54.50 / GRAM (for 200g order quantity)

Hence, for comparison purposes the price works out to be US$5,450 for 100 GRAMS

To be honest this is about what I expected it to cost from a reputable manufacturer ;)

N.B. I should add that these guys already have the SYNTHESIS ROUTE worked out, and hence do not need CAS

Thoughts? :)

BTW I am not adding anything whatsoever onto this cost and would intend to post online a copy of the PURCHASE INVOICE (as I did with COLURACETAM) ;)


Scienceguy, is this for the PHOSPHATE form used in the human trials?

#235 sunshinefrost

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Posted 17 April 2013 - 04:26 PM

Review sunshine chem's reputation if it's listed on an Alibaba exchange or similar outlet.

These drugs are not extremely expensive to synthesize, you're paying a premium for a low demand item with limited competition and scale discounts to be had through reseller bulk purchasers.


Can someone get on this and check for their reputation ?

No CAS? Isn't that a pretty big obstacle?


An obstacle, yes; but not insurmountable ;)

OK everyone, I now have all the necessary information from the EUROPEAN CUSTOM SYNTHESIS LAB :)

Details as follows:

MINIMUM PURITY: 99.5%

LEAD TIME: 4-5 Weeks

PRICE: US$ 54.50 / GRAM (for 200g order quantity)

Hence, for comparison purposes the price works out to be US$5,450 for 100 GRAMS

To be honest this is about what I expected it to cost from a reputable manufacturer ;)

N.B. I should add that these guys already have the SYNTHESIS ROUTE worked out, and hence do not need CAS

Thoughts? :)

BTW I am not adding anything whatsoever onto this cost and would intend to post online a copy of the PURCHASE INVOICE (as I did with COLURACETAM) ;)


Than I say we go with ScianceGuys supplier. 2.5 grams per participants that equates to forty participants at $136.25 plus add $5- $10 for shipping and repackaging a for a total of 141.25 or 146.25 I say just round it to $145.00 total cost for 2.5 grams.


I would go for that but some have mentionned that they would not pay too much. If some people can't pay more, i have a short list of other poeple waiting to get on the groupbuy

#236 MetaMind

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Posted 17 April 2013 - 04:32 PM

Also I dont want to be the boogey man here but how do we (the funders) know that the collector (in "pay it square") really use our money to buy NSI-189 and not some sugarpills ^^
Is there any way we can check this?
I mean at $5000 some people get seduced to inmoral actions ;-)

#237 sparkk51

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Posted 17 April 2013 - 04:34 PM

No CAS? Isn't that a pretty big obstacle?


An obstacle, yes; but not insurmountable ;)

OK everyone, I now have all the necessary information from the EUROPEAN CUSTOM SYNTHESIS LAB :)

Details as follows:

MINIMUM PURITY: 99.5%

LEAD TIME: 4-5 Weeks

PRICE: US$ 54.50 / GRAM (for 200g order quantity)

Hence, for comparison purposes the price works out to be US$5,450 for 100 GRAMS

To be honest this is about what I expected it to cost from a reputable manufacturer ;)

N.B. I should add that these guys already have the SYNTHESIS ROUTE worked out, and hence do not need CAS

Thoughts? :)

BTW I am not adding anything whatsoever onto this cost and would intend to post online a copy of the PURCHASE INVOICE (as I did with COLURACETAM) ;)


Than I say we go with ScianceGuys supplier. 2.5 grams per participants that equates to forty participants at $136.25 plus add $5- $10 for shipping and repackaging a for a total of 141.25 or 146.25 I say just round it to $145.00 total cost for 2.5 grams.


I'm still attending my first years of college and do not have a part time job, so this price is a small letdown. However, I have had major depression for the past 6 years (starting when I was 13 years old) and I'm curious as to the permanent effects this substance could have on me. Because of dosage changes to counteract tolerance, antidepressants will always be a roller-coaster ride for the rest of my life if nothing else works.

Edited by sparkk51, 17 April 2013 - 04:36 PM.


#238 NeurogenesisFactor

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Posted 17 April 2013 - 04:35 PM

With scale group buys, we might be able to afford independent testing for a few dollars per buy-in purchaser. This insurance is well worth the price.

#239 sunshinefrost

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Posted 17 April 2013 - 04:51 PM

Also I dont want to be the boogey man here but how do we (the funders) know that the collector (in "pay it square") really use our money to buy NSI-189 and not some sugarpills ^^
Is there any way we can check this?
I mean at $5000 some people get seduced to inmoral actions ;-)


not sure how to gain your trust about this but i'll probably be the receiver unless there is a better strategy. And trust me, i don't think anyone else want's this more than me .... maybe equal ;)

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#240 NeurogenesisFactor

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Posted 17 April 2013 - 04:53 PM

sunishinefrost, it sounds like you're well respected here, but independent lab testing is a good signal to buyers and incentive for a buy-in.





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