Starting a daily methylene blue journal, for those that are still unaware of this supposedly underrated nootropic.
On day one, I approximated a MB solution at about 1 mcg per drop. The calculations I used were checked multiple times for soundness, although there is an accuracy limit due to the definition of a “drop” on volume, which I assumed was about 20 drops per ml. Upon testing this using a ml syringe, it was slightly over this, but the tools I used (droppers, syringe, bottle of 1% MB itself) all produced different drop sizes with an estimated average at slightly over 20 drops per ml.
Regardless, I produced a 25ml solution containing approximately 1mcg per drop.
Day 1:
(dose 1)
I began to self-trial with my MB solution at around 4:30 on Tuesday, January 22, 2013. I decided to administer the dose orally, from the dropper, at a volume of about 1 to 3 drops. This inconsistency comes from the inability to tell how much I’m squeezing while the dropper is in my blind spot during administration. This was done sublingually – under the tongue – for superior absorption. I am unsure about MB’s oral availability when going through the GI tract, so I will continue doing this under the tongue for the trial.
After my first dose, I felt little to nothing in the first 5 minutes, but after I began to shrug off thoughts of the pointlessness of this trial, I began to feel some effects. My mind feels a bit focused. I’m neither necessarily any less clouded nor anxious, but I feel as if it’s easier to stay on track with my tasks. It’s normally a rare thing for me to be able to sit down and write as much as I have. I also feel a strange sense of energy, and my heart rate seemed to rise for a few minutes.
Similar to when I was trying sporadic doses during my winter break from college, I feel a sort of pressure near the front of my head, towards the top. If I’m not mistaken, this is the area of the brain responsible for execution and planning. Also JUST NOW I noticed that I’m typing quite well on my symbol-less DAS keyboard, which I was having trouble with before. Maybe I’m just nuts, but it really does seem a bit easier now. It might be worth noting that I put on some classical music. Brahms, piano concerto. It can make me feel badass, contributing to the energizing effects.
Not sure when this energized effect will wear off, but I’ll be sure to note it in a bit. Also, it’s perfectly reasonable to assume this is a glorified (or normal, actually) placebo effect. It could take some measures to see if it works truly or not. I’m considering making a batch of half actual doses, and half doses that are just blue food coloring made to look like MB, and compare the consistency of effects after this trial is over.
(couple hours later)
So quite a while later (it’s now 7:55), I’m still feeling pretty good. My concentration is still going. I also have felt pretty energetic and manic. At this point it’s totally either the MB at a finally perfect dose, or I’m psychologically blessed by a placebo. I have gotten so much done. The concentration effect is what’s most interesting. I can still get distracted, but this makes it easier for me to regain control and do awesome things.
Still no waning effects still have the slight pressure on the top of my head near the front, but it’s not as bad now. Pretty awesome!
Hopefully more to come tomorrow. I can be forgetful, but maybe the MB will help














