What causes elderly to lose their sense of balance? Is it simply part of cognitive decline?
What can be done about it?
Is there a term for the condition? I'm having trouble searching for it since people use the word balance for other things.
Thanks.
Posted 21 February 2013 - 04:20 AM
Posted 21 February 2013 - 12:07 PM
Posted 21 February 2013 - 02:09 PM
Posted 21 February 2013 - 02:35 PM
I prefer risedronate to alendronate, and am quite intrigued by the extra 5 years of life expectancy reported in bisphosphonate users, independent of fracture effects.
Posted 21 February 2013 - 07:19 PM
Declining stem cell function during aging contributes to impaired tissue function. Muscle-specific stem cells ('satellite cells') are responsible for generating new muscle in response to injury in the adult. However, aged muscle displays a significant reduction in regenerative abilities and an increased susceptibility to age-related pathologies. This review describes components of the satellite cell niche and addresses how age-related changes in these components impinge on satellite cell function. In particular, we review changes in the key niche elements, the myofiber and the basal lamina that are in intimate contact with satellite cells. We address how these elements are influenced by factors secreted by interstitial cells, cells of the immune system, and cells associated with the vasculature, all of which change with age. In addition, we consider more distant sources of influence on the satellite cell niche that change with age, such as neural-mediated trophic factors and electrical activity and systemic factors present in the circulation. A better understanding of the niche elements and their influence on the satellite cell will facilitate the development of therapeutic interventions aimed at improving satellite cell activity and ultimately tissue response to injury in aged individuals.
Edited by scottknl, 21 February 2013 - 07:23 PM.
Posted 21 February 2013 - 07:32 PM
Elderly lose their balance because of muscle deterioration.
Posted 21 February 2013 - 07:48 PM
You're correct about the tests etc. One could certainly argue that muscle strength could come into it when it comes to aligning the skeleton to maintain balance. Also that weaker muscles would create a delay in the physical reaction time to a signal. The process of junking up the cell niche also occurs in the nervous system too. And I suspect, but cannot prove that a similar degeneration occurs in the brain also. I love to see studies if someone has run into neuro stem cell regeneration research somewhere.Elderly lose their balance because of muscle deterioration.
That's an interesting theory, but that doesn't make sense to me. I know elderly who can jog 6 miles, but their balance is still noticeably worse than when they were younger. There's also the balance test where you close your eyes and time how long you can stand on one leg. My understanding is that the younger you are, the better your time, regardless of muscle strength. There's the related issue of reaction time, which I imagine is related. There again, the younger you are, the better your reaction time regardless of strength.
Edited by scottknl, 21 February 2013 - 07:50 PM.
Posted 21 February 2013 - 07:56 PM
Posted 21 February 2013 - 08:15 PM
I prefer risedronate to alendronate, and am quite intrigued by the extra 5 years of life expectancy reported in bisphosphonate users, independent of fracture effects.
Is there evidence bisphosphonates improve balance?
Posted 21 February 2013 - 08:33 PM
Elderly lose their balance because of muscle deterioration.
That's an interesting theory, but that doesn't make sense to me. I know elderly who can jog 6 miles, but their balance is still noticeably worse than when they were younger. There's also the balance test where you close your eyes and time how long you can stand on one leg. My understanding is that the younger you are, the better your time, regardless of muscle strength. There's the related issue of reaction time, which I imagine is related. There again, the younger you are, the better your reaction time regardless of strength.
Posted 03 March 2013 - 06:50 PM
http://www.lef.org/protocols/metabolic_health/osteoporosis_01.htmVertigo- Several recent studies have shown an association between “benign positional vertigo” (BPV) and lower bone mineral density (Vibert 2008, Jeong 2009, Vibert 2003). The inner ear, where balance is maintained, contains tiny bone particles (otoconia) that may be affected in osteoporosis (Vibert 2008). Some experts recommend that people with BPV should undergo screening for osteoporosis (Jeong 2009).
Posted 03 March 2013 - 09:18 PM
Interesting, there may be a connection between density and balance.
Vertigo- Several recent studies have shown an association between “benign positional vertigo” (BPV) and lower bone mineral density (Vibert 2008, Jeong 2009, Vibert 2003). The inner ear, where balance is maintained, contains tiny bone particles (otoconia) that may be affected in osteoporosis (Vibert 2008). Some experts recommend that people with BPV should undergo screening for osteoporosis (Jeong 2009).
Posted 13 March 2013 - 05:05 PM
Posted 08 April 2013 - 12:21 AM
Posted 08 April 2013 - 12:46 AM
Posted 09 April 2013 - 04:26 PM
Posted 01 June 2013 - 07:37 PM
Posted 02 June 2013 - 12:04 AM
Edited by AgeVivo, 02 June 2013 - 12:05 AM.
Posted 02 August 2013 - 05:32 PM
Posted 03 August 2013 - 07:11 PM
What about the cerebellum?
Many anatomical and physiological changes have been suggested as reasons for the decrease in equilibrium found in the elderly population.9-11 Abnormalities have been identified in both the central and the peripheral nervous systems.12-15 Circulatory changes (eg, atherosclerosis) may reduce blood flow to the brain stem, cerebellum, or cerebrum, potentially resulting in ischemic signs and symptoms or lesions of the nervous system.13 Musculoskeletal abnormalities in the cervical region may affect the perception of the head's position in space.16 Muscle atrophy and weakness, especially of the postural muscles, are prevalent in the aged.17-20
Posted 03 August 2013 - 10:43 PM
Posted 12 July 2015 - 06:26 PM
I wonder what exactly the association is with dementia?
An abnormal "one-leg balance" test predicts cognitive decline during Alzheimer's disease.
Rolland Y, Abellan van Kan G, Nourhashemi F, et al.
J Alzheimers Dis. 2009;16(3):525-31.
PMID: 19276547
A longitudinal study of change in falls risk and balance and mobility in healthy older people and people with Alzheimer disease.
Suttanon P, Hill KD, Said CM, Dodd KJ.
Am J Phys Med Rehabil. 2013 Aug;92(8):676-85.
PMID: 23221675
Balance and mobility dysfunction and falls risk in older people with mild to moderate Alzheimer disease.
Suttanon P, Hill KD, Said CM, Logiudice D, Lautenschlager NT, Dodd KJ.
Am J Phys Med Rehabil. 2012 Jan;91(1):12-23.
PMID: 22157433
Stroke. 2015 Jan;46(1):16-22.
Association of postural instability with asymptomatic cerebrovascular damage and cognitive decline: the Japan Shimanami health promoting program study.
Tabara Y1, Okada Y2, Ohara M2, Uetani E2, et al.
BACKGROUND AND PURPOSE:
Asymptomatic cerebral small-vessel disease (cSVD) in elderly individuals are potent risk factors for stroke. In addition to common clinical risk factors, postural instability has been postulated to be associated with cSVD in older frail patients. Here, we conducted a cross-sectional study to understand the possible link between postural instability and asymptomatic cSVD further, namely periventricular hyperintensity, lacunar infarction, and microbleeds, as well as cognitive function, in a middle-aged to elderly general population (n=1387).
METHODS:
Postural instability was assessed based on one-leg standing time (OLST) and posturography findings. cSVD was evaluated by brain MRI. Mild cognitive impairment was assessed using a computer-based questionnaire, and carotid intima-media thickness as an index of atherosclerosis was measured via ultrasonography.
RESULTS:
Frequency of short OLST, in particular <20 s, increased linearly with severity of cSVD (lacunar infarction lesion: none, 9.7%; 1, 16.0%; >2, 34.5%; microbleeds lesion: none, 10.1%; 1, 15.3%; >2, 30.0%; periventricular hyperintensity grade: 0, 5.7%; 1, 11.5%; >2, 23.7%). The association of short OLST with lacunar infarction and microbleeds but not periventricular hyperintensity remained significant even after adjustment for possible covariates (lacunar infarction, P=0.009; microbleeds, P=0.003; periventricular hyperintensity, P=0.601). In contrast, no significant association was found between posturographic parameters and cSVD, whereas these parameters were linearly associated with OLST. Short OLST was also significantly associated with reduced cognitive function independent of covariates, including cSVD (P=0.002).
CONCLUSIONS:
Postural instability was found to be associated with early pathological changes in the brain and functional decline, even in apparently healthy subjects.
PMID: 25523051
Posted 20 December 2015 - 05:00 PM
Neuropathy, as from diabetes or chemotherapy, can make balance worse too. Random references are below. I guess it makes sense. If you can't feel your feet, it makes it hard to walk. I've had my foot fall asleep sitting a certain way, and if I get up and try to walk when I can't feel my foot, it's very hard to walk.
You need several senses to be able to walk normally. In addition to a working vestibular system, you need to be able to see clearly, and your nerves need to feel the ground and position of your limbs. Then, your brain needs to be able to process that information.
Balance impairments and neuromuscular changes in breast cancer patients with chemotherapy-induced peripheral neuropathy.
Kneis S, Wehrle A, Freyler K, Lehmann K, et al.
Clin Neurophysiol. 2015 Aug 14. pii: S1388-2457(15)00735-X.
PMID: 26350407
"Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment. Resulting sensory and motor dysfunctions often lead to functional impairments like gait or balance disorders."
Sensory Functions, Balance, and Mobility in Older Adults With Type 2 Diabetes Without Overt Diabetic Peripheral Neuropathy: A Brief Report.
Deshpande N, Hewston P, Aldred A.
J Appl Gerontol. 2015 Aug 30. pii: 0733464815602341. [Epub ahead of print]
PMID: 26324522
"Subtle changes in multiple sensory systems of older adults with T2D may reduce redundancy available for balance control while performing challenging activities much before DPN development."
Impact of Type-2 Diabetes Time Since Diagnosis on Elderly Women Gait and Functional Status.
da Cruz Anjos DM, de Souza Moreira B, Pereira DS, et al.
Physiother Res Int. 2015 Aug 18.
PMID: 26284942
"Type-2 diabetes mellitus time since diagnosis has a negative impact on gait speed and step length..."
The influence of diabetic peripheral neuropathy on local postural muscle and central sensory feedback balance control.
Toosizadeh N, Mohler J, Armstrong DG, Talal TK, Najafi B.
PLoS One. 2015 Aug 10;10(8):e0135255. doi: 10.1371/journal.pone.0135255. eCollection 2015.
PMID: 26258497
"Poor balance control and increased fall risk have been reported in people with diabetic peripheral neuropathy (DPN).... DPN participants were highly unstable compared to controls. However, as soon as they perceived the magnitude of sway using sensory feedback, they chose a high rigid postural control strategy, probably due to high concerns for fall, which may increase the energy cost during extended period of standing; the adaptation mechanism using sensory feedback depends on the level of neuropathy and the history of diabetes."
Diabetic peripheral neuropathy compromises balance during daily activities.
Brown SJ, Handsaker JC, Bowling FL, Boulton AJ, Reeves ND.
Diabetes Care. 2015 Jun;38(6):1116-22. doi: 10.2337/dc14-1982. Epub 2015 Mar 12.
PMID: 25765355
"Patients with diabetes with peripheral neuropathy have a well-recognized increased risk of falls.... Greater separations of the center of mass from the center of pressure present a greater challenge to balance. Therefore, the higher medial-lateral separations found in patients with DPN will require greater muscular demands to control upright posture. This may contribute to explaining why patients with DPN are more likely to fall, with the higher separations placing them at a higher risk of experiencing a sideways fall than nondiabetic control subjects."
Edited by ta5, 20 December 2015 - 05:00 PM.
Posted 20 December 2015 - 07:02 PM
What causes elderly to lose their sense of balance? Is it simply part of cognitive decline?
What can be done about it?
.
Posted 20 December 2015 - 07:51 PM
What causes elderly to lose their sense of balance? Is it simply part of cognitive decline?
There are many reasons. The most important is the neuronal regulation from the brain. It detoriates with the age, e.g. you are right - it is the cognitive decline.
What can be done about it?
Prevention of falls: remove things that the elderly can step wrong on. It will be best if elders especially demented not fiddle arround very much.
What can be done about it: Many things, including wheelchair.
Is there a term for the condition? I'm having trouble searching for it since people use the word balance for other things.
There are many terms since there are many reasons for elders falling.
Posted 22 December 2015 - 06:00 PM
The fast-twitch muscle loss and neurological decline in balance organs sound likely culprits to me, when it comes to falling. The cataract thing is easy to explain, as there's a visual component in holding your balance - that's why it's harder when your eyes are closed, obviously.
Athletes do all kinds of drills to improve their speed and agility, I wonder if this kind of things could be adapted for the elderly as well. Make them play Dance Dance Revolution?
Edited by proileri, 22 December 2015 - 06:12 PM.
Posted 23 December 2015 - 06:27 AM
I think it's a common assumption that elderly people break their hips when they loose their balance and fall. But I heard specialists say it's usually the other way around. Instead, their bones are so weak that they break on their own or from a slightest exertion (like sneezing) which then causes elderly to fall.
Posted 23 December 2015 - 07:21 AM
Unlikely. If their bones can break from a sneeze, then when they fall, their entire skeleton should turn into a bag of bone pieces lol.
Posted 23 December 2015 - 07:43 AM
Unlikely. If their bones can break from a sneeze, then when they fall, their entire skeleton should turn into a bag of bone pieces lol.
Maybe you should speak to the elderly who fell and specialists who tend to them -? 'cause what they say contradicts to what you seems likely to you.
btw, here you make another faulty assumption, that all bones deteriorate at the same rate. better watch out for those faulty assumptions
Posted 23 December 2015 - 08:59 AM
My personal opinion is that the majority of the falls are due to insuficiency of the receptors for the balance and the parts of the brain, that respond for keeping balance.
Old people fall down some times without to loose consciousness, and without to step wrong, or without to slip. They simply fall. I saw this several times with my late grand-mother. She broke her leg after the 6-th or the 7-th fall. This definately do not correlate with the point, that old people fall, because they break their legs before the fall. One of the falls she said it exactly as it is "Wow. I fell. Why is that?"
The reason is that the parts of the brain, that hold you straight don't work well anymore. Just like each part of the brain, that partivcular part gets age related degeneration too. Its neurons are simply no longer there.
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