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jdtic kappa antagonist bulk/group buy


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#571 KieranA001

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Posted 20 February 2014 - 06:16 PM

Something else you may want to look into would be pregnenolone. I have been taking this stuff at 100mg for about a week now and my dissociation has nearly gone, it also has anti-depression and anti-anxiety properties. I kinda just feel calm, like I just don't give a damn, well I wouldn't go that far but I feel less serious about everything. It's really great stuff. :-) My mood is so much better, I cannot tell you how much this stuff is helping me at the moment.

http://en.wikipedia....ki/Pregnenolone

It's suppose to boost memory and balance out hormones as well. I haven't noticed a big difference with memory though but I'm wondering if it's just a hormone imbalance that I have. Don't know. :L

#572 KieranA001

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Posted 20 February 2014 - 07:49 PM

Do you think JDTic can be used for ADHD ? :-)

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#573 Strangelove

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Posted 20 February 2014 - 09:30 PM

Impressive how much interest this compound gathers, its a relatively new thread, but has the most replies in the mental health subforum. I wish I had some spare money to try it.

#574 BigPapaChakra

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Posted 21 February 2014 - 12:45 AM

Damn, so I'm too late to the party, lol?

#575 Steve Zissou

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Posted 21 February 2014 - 02:25 AM

Ok so i received the salvia tincture in the post today and took one drop sublignually.

I felt slight dissosiation, a little bit of nausea and laziness for about 20 mins. It wasn't enjoyable, but it was bearable. My heartbeat also became louder (I could hear it).

It's been about 40 mins since I took the dose, and there is a real reduced stress/anti-anxiety effect. My concentration seems to have improved slightly also.

I will continue dosing to see if these effects can be ampllified.

However one thing has me a little confused. On wikipedia it states that, "The longer effects of κ-opioid agonism (30 minutes or greater) have been linked to κ-opioid receptor-dependent stress-induced potentiation and reinstatement of drug seeking. It is hypothesized that these behaviors are mediated by κ-opioid-dependent modulation of dopamine, serotonin, or norepinephrine and/or via activation of downstream signal transduction pathways."

Does this mean that longer than 30 mins or more than one dosage per day will induce negative changes in the brain instead of positive changes?

#576 celebes

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Posted 21 February 2014 - 02:54 AM

However one thing has me a little confused. On wikipedia it states that, "The longer effects of κ-opioid agonism (30 minutes or greater) have been linked to κ-opioid receptor-dependent stress-induced potentiation and reinstatement of drug seeking. It is hypothesized that these behaviors are mediated by κ-opioid-dependent modulation of dopamine, serotonin, or norepinephrine and/or via activation of downstream signal transduction pathways."

Does this mean that longer than 30 mins or more than one dosage per day will induce negative changes in the brain instead of positive changes?


Very, very basically this means short-term agonism is analgesic and anti-addictive, while long-term agonism develops into the dysphoria and anhedonia we've been talking about, which predispose to drug-seeking to alleviate them. It does somewhat imply acute, high-dose kappa agonism would be best for downregulation. That said. I'd be at a loss to quantify 'somewhat' for you.

Good to hear positive results so far though.

Edited by celebes, 21 February 2014 - 02:55 AM.


#577 Steve Zissou

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Posted 22 February 2014 - 12:40 PM

An update:

Ok so today is the end of my second day. I took 4 drops today which was very mild. No dissosiation, and my body seemed very relaxed.

I originally became interested in this because I have been trying to give up pmo (porn/masturbation) for about a year, but the furtherest I got was about a week before I relapsed. I beleive that years of thrasing my dopamine receptors everyday has lead to anhedonia, low motivation, lack of desire to socialize etc. After a couple of days of giving it up, I feel great, but I always seemed to go back to old habits.

So current changes:
Haven't relapsed so far. Self control seems much easier.
I'm updating my progess in this thread. Usually I would start something and forget about it.
Massive increase in body temperature. I can feel the heat pulsating through my body right now. Nice change from being cold all the time.
I feel... happy?

During the day I felt fine, not great, but just fine. However right now (Night time where I am) I am feeling great. My whole body is warm, my brain is tingling and I am in a positive mood. Is this what feeling happy feels like? It honestly is a feeling of love (which is strange because there is nobody I have feelings for). Just noticing now but the negative mental chatter has disappeared in my brain. Things which usually would hurt my feelings didn't get to me that much.

I don't expect these positive feelings to last so long, but I am enjoying them right now. I am mostly hoping my self control stays strong. I will continue to dose daily and will give an update tommorrow.

#578 socialpiranha

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Posted 22 February 2014 - 12:57 PM

Thats good news steve, i don't want to sound rude but you should probably start a new thread if you plan on doing a daily update, i'd like to keep this thread as close as possible to the original topic. Looking forward to following your results!

#579 Missjess

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Posted 22 February 2014 - 01:08 PM

Hi guys, I should be trying jdtic next week. My Canadian friend will be arriving on Monday and he will bring the jdtic for me to try...he has 2.5 or 3 grams left I think. Can anyone give me an idea if how much to try? I have extreme dissociation from using Iboga and extreme dp to the point where I cannot sense my arms when I move them they feel totally detached. I hope to god that it is the kappa receptor causing this and if can be reversed by using jdtic...

#580 KieranA001

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Posted 22 February 2014 - 03:04 PM

Well, I just have to say I don't like this stuff at all. I didn't have enough money to buy socialpiranhas JDTic before he made the private group. But I obtained it elsewhere and it's just not for me. I hope it works out for you guys but I think it could have killed me if I didn't spit it out and wash my mouth out with water in time.

I placed a small, tiny crystal of it under my tongue (probably not even 100mcg) and it has a very punjant taste to it, very bitter. I put it under my tongue for about 30 seconds and started to come over all weird. I firstly started to loose consciousness which is the point when I thought to myself (fuck this) and just spat it out. I then started to get rapid heartbeat and felt very very dysphoric. It felt like I drunk 30 coffees.

I have had this weird feeling over my for about three hours now, and I just feel plane. Don't feel happy, don't feel depressed just very dysphoric. I have been getting chest pains occasionally and all these symptoms get worse occasionally (gets worse in waves). Right now, I feel slightly better. I took the stuff at around 11:00AM ish today.

I hope it doesn't effect me anymore. I notice I have to focus on my breathing, I cannot seem to feel myself breathe. It's like I have to manually take over and it's really bad when I watch TV. I have to get up and move about and take deep breathes to get myself feeling somewhat better again.

All I have to say, if you're going to use this stuff, then don't underestimate how strong this stuff is. Even though I didn't take that much at all. I only used one crystal (just a pinpricks worth. )

#581 socialpiranha

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Posted 22 February 2014 - 03:24 PM

where did you get it from kieran?

#582 penisbreath

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Posted 22 February 2014 - 03:28 PM

That's really depressing to hear. Glad you're okay, though, Kieran.

#583 socialpiranha

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Posted 22 February 2014 - 03:31 PM

Hi guys, I should be trying jdtic next week. My Canadian friend will be arriving on Monday and he will bring the jdtic for me to try...he has 2.5 or 3 grams left I think. Can anyone give me an idea if how much to try? I have extreme dissociation from using Iboga and extreme dp to the point where I cannot sense my arms when I move them they feel totally detached. I hope to god that it is the kappa receptor causing this and if can be reversed by using jdtic...


Your canadian friend is part of my group buy why would he have three grams of the stuff and be going to australia with it?

kieran it sounds like someone gave you some sort of poison, very few things are that active at that dose and i highly doubt jdtic would have that effect

#584 KieranA001

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Posted 22 February 2014 - 03:35 PM

where did you get it from kieran?


Well because I didn't have enough to buy yours and seen as when I did get the amount needed you'd already made a private group so I brought it from another member on here because you would have already sent off for it. But, above all that I just wanted to let you know just so you're careful with it because I have just realized how much that stuff can mess you up. I still feel really dodgy and would highly recommend you buying a digital scale so you can precisely measure it out. I don't think I will be trying anymore, it doesn't agree with me.

I will let you know how I'm feeling tomorrow depending if I'm still able to wake up. My fingers and feel are very cold and I feel very messed up right about now. I will give it the benefit of the doubt and wait it out overnight and see how I feel in the morning. I won't be sleeping because I feel too messed up to sleep. Every time I sit down the effects get worse. Really didn't expect this from it anyway.

It was JDTic. I can clarify that. It gave me the same effect as when I took Salvia, the same rapid heartbeat but I feel that JDTic feels like it's 100x more potent. The effects are worse than taking Salvia. It says JDTic written on it and I have the paperwork and everything. It also makes you sweat like a pig.

It should be fine for you guys, perhaps it just doesn't agree with me or something. I'm only 18 so perhaps my heart hasn't fully grown or something.

Edited by KieranA001, 22 February 2014 - 03:38 PM.


#585 Missjess

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Posted 22 February 2014 - 03:38 PM

Hi guys, I should be trying jdtic next week. My Canadian friend will be arriving on Monday and he will bring the jdtic for me to try...he has 2.5 or 3 grams left I think. Can anyone give me an idea if how much to try? I have extreme dissociation from using Iboga and extreme dp to the point where I cannot sense my arms when I move them they feel totally detached. I hope to god that it is the kappa receptor causing this and if can be reversed by using jdtic...


Your canadian friend is part of my group buy why would he have three grams of the stuff and be going to australia with it?

kieran it sounds like someone gave you some sort of poison, very few things are that active at that dose and i highly doubt jdtic would have that effect


No he is not part of the group buy as I said he purchased it himself a few weeks ago he has half left for me to try but after hearing about Kieran's response I'm rlly hesitant and paranoid about taking it..

#586 socialpiranha

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Posted 22 February 2014 - 03:39 PM

maxime is part of the group buy

#587 Missjess

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Posted 22 February 2014 - 03:41 PM

where did you get it from kieran?


Well because I didn't have enough to buy yours and seen as when I did get the amount needed you'd already made a private group so I brought it from another member on here because you would have already sent off for it. But, above all that I just wanted to let you know just so you're careful with it because I have just realized how much that stuff can mess you up. I still feel really dodgy and would highly recommend you buying a digital scale so you can precisely measure it out. I don't think I will be trying anymore, it doesn't agree with me.

I will let you know how I'm feeling tomorrow depending if I'm still able to wake up. My fingers and feel are very cold and I feel very messed up right about now. I will give it the benefit of the doubt and wait it out overnight and see how I feel in the morning. I won't be sleeping because I feel too messed up to sleep. Every time I sit down the effects get worse. Really didn't expect this from it anyway.

It was JDTic. I can clarify that. It gave me the same effect as when I took Salvia, the same rapid heartbeat but I feel that JDTic feels like it's 100x more potent. The effects are worse than taking Salvia. It says JDTic written on it and I have the paperwork and everything. It also makes you sweat like a pig.

It should be fine for you guys, perhaps it just doesn't agree with me or something. I'm only 18 so perhaps my heart hasn't fully grown or something.


Shit...the more I read about ur experience the less I want to try it!! R u sure u didn't take salvia ?? I don't want to feel a rapid heart beat or sweat like a pig!! Fuk that

maxime is part of the group buy


Did he pay for it already? Well perhaps he will be getting more from ur buy who knows

#588 celebes

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Posted 22 February 2014 - 03:45 PM

Kieran, I don't think what you took was JDTic. The effect should be the exact opposite of taking Salvia. That is simply a consequence of the pharmacology. Who sold it to you and for how much?

#589 KieranA001

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Posted 22 February 2014 - 03:46 PM

It definitely wasn't Salvia. It might just be me, I might have just been overly sensitive to it. All I'm saying is that when you're taking it take the smallest dose you can put into your mouth. I would rather have anxiety and depression all my life then put up with these effects for a day! Just being alive is good enough for me. It really dose make you appreciate life more though. Hasn't done anything for my dissociation, it's hard to tell at the moment I just feel so weird (it's hard to describe the feeling) I just feel really dodgy inside.

#590 Missjess

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Posted 22 February 2014 - 03:49 PM

It definitely wasn't Salvia. It might just be me, I might have just been overly sensitive to it. All I'm saying is that when you're taking it take the smallest dose you can put into your mouth. I would rather have anxiety and depression all my life then put up with these effects for a day! Just being alive is good enough for me. It really dose make you appreciate life more though. Hasn't done anything for my dissociation, it's hard to tell at the moment I just feel so weird (it's hard to describe the feeling) I just feel really dodgy inside.


This is really disturbing ....if I can't take jdtic I don't know what else to take to rid myself of the Iboga induced dissociation and I cannot accept to live with this for the rest of my life. Not sure if I shud try it or not at this point :(

#591 KieranA001

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Posted 22 February 2014 - 03:50 PM

Kieran, I don't think what you took was JDTic. The effect should be the exact opposite of taking Salvia. That is simply a consequence of the pharmacology. Who sold it to you and for how much?


It was definitely JDTic, I think you have to put up with negative effects before the good effects begin to kick in. I'm guessing that when the JDTic binds to to Kappa receptor site your whole brain chemistry has to change itself. (I think) The dysphoria and that might go away. I will let you know if I feel better in the morning.

It was definitely JDTic though. I can assure you that.

#592 socialpiranha

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Posted 22 February 2014 - 03:51 PM

where did you get it from kieran?


Well because I didn't have enough to buy yours and seen as when I did get the amount needed you'd already made a private group so I brought it from another member on here because you would have already sent off for it. But, above all that I just wanted to let you know just so you're careful with it because I have just realized how much that stuff can mess you up. I still feel really dodgy and would highly recommend you buying a digital scale so you can precisely measure it out. I don't think I will be trying anymore, it doesn't agree with me.

I will let you know how I'm feeling tomorrow depending if I'm still able to wake up. My fingers and feel are very cold and I feel very messed up right about now. I will give it the benefit of the doubt and wait it out overnight and see how I feel in the morning. I won't be sleeping because I feel too messed up to sleep. Every time I sit down the effects get worse. Really didn't expect this from it anyway.

It was JDTic. I can clarify that. It gave me the same effect as when I took Salvia, the same rapid heartbeat but I feel that JDTic feels like it's 100x more potent. The effects are worse than taking Salvia. It says JDTic written on it and I have the paperwork and everything. It also makes you sweat like a pig.

It should be fine for you guys, perhaps it just doesn't agree with me or something. I'm only 18 so perhaps my heart hasn't fully grown or something.


jdtic has the opposite effect as salvia , salvia is an agonist and jdtic is an antagonist.. I am afraid you just fell prey to someone who saw an opportunity to take advantage of you. I had a feeling tritium tricked you when you dropped out. And now misjess is believing some dude has 3 grams of it??, just for the record that would cost over $20,000 . you guys are so gullible it's not even funny, seriously.

#593 Strangelove

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Posted 22 February 2014 - 03:54 PM

Really perplexed about this, any way to send a sample for analysis? Just hang on it, maybe another member can help analysing your batch?

#594 celebes

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Posted 22 February 2014 - 03:54 PM

It was definitely JDTic, I think you have to put up with negative effects before the good effects begin to kick in. I'm guessing that when the JDTic binds to to Kappa receptor site your whole brain chemistry has to change itself. (I think) The dysphoria and that might go away. I will let you know if I feel better in the morning.

It was definitely JDTic though. I can assure you that.


Who sold it you, how much did they charge and how did you pay them?

#595 Strangelove

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Posted 22 February 2014 - 03:55 PM

As you probably many know, David Pearce and I believe some of his acguaintances already use it with very good results. I already send him a message to see if he has anything to say about this.

Edited by Strangelove, 22 February 2014 - 04:00 PM.


#596 KieranA001

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Posted 22 February 2014 - 03:59 PM

where did you get it from kieran?


Well because I didn't have enough to buy yours and seen as when I did get the amount needed you'd already made a private group so I brought it from another member on here because you would have already sent off for it. But, above all that I just wanted to let you know just so you're careful with it because I have just realized how much that stuff can mess you up. I still feel really dodgy and would highly recommend you buying a digital scale so you can precisely measure it out. I don't think I will be trying anymore, it doesn't agree with me.

I will let you know how I'm feeling tomorrow depending if I'm still able to wake up. My fingers and feel are very cold and I feel very messed up right about now. I will give it the benefit of the doubt and wait it out overnight and see how I feel in the morning. I won't be sleeping because I feel too messed up to sleep. Every time I sit down the effects get worse. Really didn't expect this from it anyway.

It was JDTic. I can clarify that. It gave me the same effect as when I took Salvia, the same rapid heartbeat but I feel that JDTic feels like it's 100x more potent. The effects are worse than taking Salvia. It says JDTic written on it and I have the paperwork and everything. It also makes you sweat like a pig.

It should be fine for you guys, perhaps it just doesn't agree with me or something. I'm only 18 so perhaps my heart hasn't fully grown or something.


jdtic has the opposite effect as salvia , salvia is an agonist and jdtic is an antagonist.. I am afraid you just fell prey to someone who saw an opportunity to take advantage of you. I had a feeling tritium tricked you when you dropped out. And now misjess is believing some dude has 3 grams of it??, just for the record that would cost over $20,000 . you guys are so gullible it's not even funny, seriously.



Well to be honest the after-effects of Salvia were good. With JDTic I feel dysphoric, jittery, anxious, and have a weird feeling inside. He didn't take advantage of us, I dropped out because I didn't have enough money at the time then I got the money together again and by then it was too late to opt back in again because you said you were closing purchases of it. So I brought it elsewhere.

How did he trick us? I'd like to know that. I just wanted to let you guys know because I don't want it to mess up guys up like it just did with me.

#597 Missjess

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Posted 22 February 2014 - 03:59 PM

Hey mayb I got the dosage wrong but he has 3 or 2.5 something left its equivalent to 1 dosage that they have in the trials. What is after mcg ? I'm not a fuking measurement person lol

#598 socialpiranha

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Posted 22 February 2014 - 04:01 PM

It definitely wasn't Salvia. It might just be me, I might have just been overly sensitive to it. All I'm saying is that when you're taking it take the smallest dose you can put into your mouth. I would rather have anxiety and depression all my life then put up with these effects for a day! Just being alive is good enough for me. It really dose make you appreciate life more though. Hasn't done anything for my dissociation, it's hard to tell at the moment I just feel so weird (it's hard to describe the feeling) I just feel really dodgy inside.


You have zero way of knowing what you took and you won't even tell us who you bought it from ? What if it was some psychopath sending people strichnine, god knows who else bought it from him, there's a reason he is making deals by pm and not starting his own threads

#599 KieranA001

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Posted 22 February 2014 - 04:04 PM

It was definitely JDTic, I think you have to put up with negative effects before the good effects begin to kick in. I'm guessing that when the JDTic binds to to Kappa receptor site your whole brain chemistry has to change itself. (I think) The dysphoria and that might go away. I will let you know if I feel better in the morning.

It was definitely JDTic though. I can assure you that.


Who sold it you, how much did they charge and how did you pay them?


The guy who sold it to me might not want me to tell you (I respect his privacy) but all in all it was JDTic < 97% tested about a month ago. It's JDTic, it even has it on the bottle and the bottle was sealed tight and was from Medchem Express. I might be feeling great tomorrow, who knows!

My dissociative symptoms seem to be clearing actually. It's hard to tell. The effects straight after you take it are crappy. Three hours after i felt slightly better now it's 4:09PM and I feel slightly better (dysphoric wise)

Edited by KieranA001, 22 February 2014 - 04:09 PM.


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#600 Missjess

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Posted 22 February 2014 - 04:08 PM

socialpiranha

You are very very stubborn ...he is only trying to warn everyone who wants to try jdtic and I for one am so glad that he did!!
Tritium bought his jdtic from medchem so it certainly wasn't dodgy stuff. There is a reason why they stopped doing the trials...that fast heart beat thing came up in trials.

Why would 2 people both lie about there experiences ?? They have no reason too!!

It was definitely JDTic, I think you have to put up with negative effects before the good effects begin to kick in. I'm guessing that when the JDTic binds to to Kappa receptor site your whole brain chemistry has to change itself. (I think) The dysphoria and that might go away. I will let you know if I feel better in the morning.

It was definitely JDTic though. I can assure you that.


Who sold it you, how much did they charge and how did you pay them?


The guy who sold it to me might not want me to tell you (I respect his privacy) but all in all it was JDTic < 97% tested about a month ago. It's JDTic, it even has it on the bottle and the bottle was sealed tight and was from Medchem Express. I might be feeling great tomorrow, who knows!

My dissociative symptoms seem to be clearing actually. It's hard to tell.


Plz keep me updated on ur progress as I am very interested to hear how it affects ur dissociation!!! That's my main reason for wanting to try it
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