387 replies to this topic

[uralsky]

Manufacturer needed it to be in solution in order to aliquot equal amounts for each user. That does not mean they had to ship it this way. I expected they would use nontoxic volatile solvent like alcohol to split and then dry it out before shipping. The end users could easily redissolve it in a solvent, like vodka.

[phil8462643]

Here is how I deal with dropper caps before travelling. I pull off the rubber lid from the dropper. slide the glass tube out, put a cellophane on the top of the bottle, mold it to cover the top, then screw the plastic dropper holder on.
Updates please?
...

[Werper]

I got my bottle yesterday, thanks.

[chemicalambrosia]

I got my bottle yesterday, thanks.

I got mine yesterday as well.

[aarfai]

I also received mine yesterday. With that being said, how do I dose and store it? IIRC yada mentioned 6.6 drops?

[datrat]

Thanks Yadayada for putting this all together, I know it's been a long slog. And thanks Q did it for doing the dirty work of mailing the bottles out.

I got mine yesterday, mail comes late to us so I wasn't able to try it until around 4 pm. My first subjective feelings after dosing yesterday and again this morning are very favorable. While it can certainly be placebo effect, I notice some interesting feelings. If I think of things that normally piss me off, I get pissed off, but not excessively so. But if I think of things that make me feel good, or am just enjoying the moment I'm in, I get this very pleasant happy feeling. It's definitely not euphoric or giddy and can go away. But I haven't had this just pleasant feeling in 7 - 8 years, which coincides with when I started SNRI's/SSRI's and I've really been struggling with anhedonia since that point. I really did forget this type of feeling, so I'm not sure if it's just a placebo effect, but regardless, it's pretty nice.

One question I have; I realize that I don't recall reading what the half of BPAP is in any of the descriptions of it's mode of action. Does anyone know it's half life?

[Reformed-Redan]

I also received mine yesterday. With that being said, how do I dose and store it? IIRC yada mentioned 6.6 drops?

Just store it in the fridge.

Thanks Yadayada for putting this all together, I know it's been a long slog. And thanks Q did it for doing the dirty work of mailing the bottles out.

I got mine yesterday, mail comes late to us so I wasn't able to try it until around 4 pm. My first subjective feelings after dosing yesterday and again this morning are very favorable. While it can certainly be placebo effect, I notice some interesting feelings. If I think of things that normally piss me off, I get pissed off, but not excessively so. But if I think of things that make me feel good, or am just enjoying the moment I'm in, I get this very pleasant happy feeling. It's definitely not euphoric or giddy and can go away. But I haven't had this just pleasant feeling in 7 - 8 years, which coincides with when I started SNRI's/SSRI's and I've really been struggling with anhedonia since that point. I really did forget this type of feeling, so I'm not sure if it's just a placebo effect, but regardless, it's pretty nice.

One question I have; I realize that I don't recall reading what the half of BPAP is in any of the descriptions of it's mode of action. Does anyone know it's half life?

I think the h/l is 6h but from my experiences i redosed at the 4h mark. Similar experiences here.

Q did it! I'm trying to organize your portion of BPAP. Just a little patience.

[uralsky]

got mine. all wet outside and ~60% full. Excited to start dosing today.
Regarding storage: keeping it in refrigerator would not be very convenient as every day it would need to be thawed. Perhaps keeping part of it separately frozen, and smaller amount as liquid for every day use?
Anyway, how do we track stability of it? By subjective experience?

Should we assume the exact concentration is 300 ug/mL? Please correct me.

[boff]

Anyone in Australia recieved theirs yet?

[sparkk51]

Received mine. I've never tried DMSO, but holy shit this stuff is nasty. Easily the worst tasting chemical so far.

[Reformed-Redan]

got mine. all wet outside and ~60% full. Excited to start dosing today.
Regarding storage: keeping it in refrigerator would not be very convenient as every day it would need to be thawed. Perhaps keeping part of it separately frozen, and smaller amount as liquid for every day use?
Anyway, how do we track stability of it? By subjective experience?

Should we assume the exact concentration is 300 ug/mL? Please correct me.

Yes. Stability shouldn't be an issue that much as long as it is stored away from light and in a fridge.

[sparkk51]

Guys, I took one drop. This stuff isn't placebo. I am not saying its euphoric or amazing but I feel different when focusing.

[Multicultural Harmony]

got mine. all wet outside and ~60% full. Excited to start dosing today.
Regarding storage: keeping it in refrigerator would not be very convenient as every day it would need to be thawed. Perhaps keeping part of it separately frozen, and smaller amount as liquid for every day use?
Anyway, how do we track stability of it? By subjective experience?

Should we assume the exact concentration is 300 ug/mL? Please correct me.

Yes. Stability shouldn't be an issue that much as long as it is stored away from light and in a fridge.

Great work Yadayada in organizing this!

Everyone PLEASE keep the experience reports rolling in!

So far they sound good. You may have found something unique here.

Edited by Pitolisant, 01 January 2014 - 10:45 PM.

[aarfai]

I really don't understand the dosing... Is one suppose to drop(s) the solution sublingually as is or dilute it even further?

[Reformed-Redan]

I really don't understand the dosing... Is one suppose to drop(s) the solution sublingually as is or dilute it even further?

You can just do 6 drops sublingual.

[meatsauce]

Has everyone got thier's yet? Im in az. I can't wait to try it!

[Multicultural Harmony]

Any long term studies done yet w/this drug in terms of safety/toxicology?

[Reformed-Redan]

Any long term studies done yet w/this drug in terms of safety/toxicology?

Paul Wakfer is your n=1 sample for long term use of BPAP.

[Multicultural Harmony]

Hmm... I'll wait for more clinical trials, although it does seem interesting.

Right now too focused on improvement of circadian rhythm and metabolism. An approach that seems to be working ok, not quite as much as I'd like though. Hopefully everyone benefits from this BPAP gunk and without complications.

[uralsky]

got mine. all wet outside and ~60% full. Excited to start dosing today.
Regarding storage: keeping it in refrigerator would not be very convenient as every day it would need to be thawed. Perhaps keeping part of it separately frozen, and smaller amount as liquid for every day use?
Anyway, how do we track stability of it? By subjective experience?

Should we assume the exact concentration is 300 ug/mL? Please correct me.

Yes. Stability shouldn't be an issue that much as long as it is stored away from light and in a fridge.

Would it be correct then that the total amount we receive is about 10 mg?

[phil8462643]

its no different from all the other research materials discussed on this site (not many clinical trials), except that the chemist who invented this one has my trust.

got mine. all wet outside and ~60% full. Excited to start dosing today.
Regarding storage: keeping it in refrigerator would not be very convenient as every day it would need to be thawed. Perhaps keeping part of it separately frozen, and smaller amount as liquid for every day use?
Anyway, how do we track stability of it? By subjective experience?

Should we assume the exact concentration is 300 ug/mL? Please correct me.

Yes. Stability shouldn't be an issue that much as long as it is stored away from light and in a fridge.

Would it be correct then that the total amount we receive is about 10 mg?

No. 1/10g = 100mg = 100,000mcg = somewhere near 1000 doses

[Hebbeh]

its no different from all the other research materials discussed on this site (not many clinical trials), except that the chemist who invented this one has my trust.

got mine. all wet outside and ~60% full. Excited to start dosing today.
Regarding storage: keeping it in refrigerator would not be very convenient as every day it would need to be thawed. Perhaps keeping part of it separately frozen, and smaller amount as liquid for every day use?
Anyway, how do we track stability of it? By subjective experience?

Should we assume the exact concentration is 300 ug/mL? Please correct me.

Yes. Stability shouldn't be an issue that much as long as it is stored away from light and in a fridge.

Would it be correct then that the total amount we receive is about 10 mg?

No. 1/10g = 100mg = 100,000mcg = somewhere near 1000 doses

Well if a dose is 6 drops, there is no way you're going to squeeze 6000 drops out of that bottle. Just sayin.

[phil8462643]

16 drops in a ml roughly. 6000/16 = 375. Either the bottle is 375ml (does not look like it is) or a dose is not 6 drops, or we have not been given 100mg

[Hebbeh]

16 drops in a ml roughly. 6000/16 = 375. Either the bottle is 375ml (does not look like it is) or a dose is not 6 drops, or we have not been given 100mg

I'd eyeball that as a typical 50 ml medicine bottle. 375 ml would be like a large bottle of olive oil.

[phil8462643]

if these drops are normal size drops, there should be 16 drops in a ml. if there is 1 mg in a ml, then 1 drop should be 62.5mcg! If the info we have been given is correct then a dose should be no more than 2 drops

[Hebbeh]

if these drops are normal size drops, there should be 16 drops in a ml. if there is 1 mg in a ml, then 1 drop should be 62.5mcg! If the info we have been given is correct then a dose should be no more than 2 drops

Sounds better. I wont have a chance to test it till the weekend but a drop sounds like a good starting point.

[Multicultural Harmony]

Received mine. I've never tried DMSO, but holy shit this stuff is nasty. Easily the worst tasting chemical so far.

DMSO's odor is very pungent, I wouldn't really want to ingest it. lol. This is getting funny.

[sparkk51]

Guys, I left the BPAP in the refrigerator last night. I took it out just now and it's frozen. I am no chemistry student, but should this stuff freeze in the average refrigerator? I can't tell the temperature it's set at but the other liquids aren't frozen ><.

Edited by sparkk51, 02 January 2014 - 02:32 PM.

[uralsky]

It is actually serious question.
The bottle has ~ 30 mL of 300 ug/mL solution (as confirmed by yadayada) which makes ~10 mg total. If it is 100 mg: then actual concentration is more like 3 mg/mL?
Can we get a word from the manufacturer what is the concentration?

[Nattzor]

Guys, I left the BPAP in the refrigerator last night. I took it out just now and it's frozen. I am no chemistry student, but should this stuff freeze in the average refrigerator? I can't tell the temperature it's set at but the other liquids aren't frozen ><.

Different liquids have different freezing points.