7 replies to this topic

[Fred Downson]

Hello!

I joined this site because many of you share my interest in C60.

I am personally starting C60 on the 3rd of next month and will continue taking it as long as I'm alive. My reasoning is pretty obvious, I want to contribute to the scientific community and of course, live longer. Combined with this I will be starting a severe low calorie diet, eating as little as possible BUT getting as much of the required nutrients into my body as possible.

My question is this: What would you like to see documented?

[niner]

My question is this: What would you like to see documented?

How about athletic performance on a defined task, where you would monitor the time it takes you to complete an aerobic challenge, or the number of reps that you can lift using a weight that you can do 3-8 reps at most. This would need to be something you'd trained on for a while so there wasn't a big training effect. Another thing you could measure would be your heart rate at 0, 1, and 2 minutes after a defined aerobic task. You'd want to do these things several times prior to starting c60, and several times after.

Starting CR, particularly extreme CR at the same time is going to make it more difficult to tell which effects are due to what. It might be better to separate the start times by a month or so. I'm not a CR expert, but my understanding is that doing it right requires that you ease into it. I don't think you want to start an extreme regimen all at once.

[hav]

Here's a link to another related thread...

http://www.longecity...post__p__637958

Howard

[kmoody]

I would recommend getting labs and a complete physical done a least once before starting so that you have a baseline from which to compare the effects of your approach. I would also strongly recommend conducting your experiment under the supervision of/in consultation with a licensed physician. They can help keep a good record of any effects -- positive or negative -- and make this project safer for you. Any changes in dose, frequency, or source should be documented. A personal journal that describes your subjective perception may also be a good idea. Document any changes, good or bad, large or small, that you notice. As Niner suggests, functional tests could be useful. If I were to do anything like this I would select several tests that could be done periodically, and just make a big excel spreadsheet to track changes over time. Likewise with the labs. I would redo labs at least monthly if I could afford it, else quarterly or every 6 months.

[Jochen]

How much C60 will you be taking?

interesting things to document:

• set a baseline like kmoody suggests (with intervals of retesting)
• like Niner already mentioned, your fitness regime and results
• would also suggest mood self-assessment
• nutrition
• sleep
• other factors (like stress at work, brain training, ...)

Good luck with this self-experiment!

[Bogomoletz II]

Wasn't there a study published not too long ago detailing how calorie restriction didn't increase the lifespans of some research orangutans? In respect to longevity, it's less risky for you not to adopt any kind of crazy diets. Might win, might lose.

Edited by Bogomoletz II, 13 February 2014 - 09:48 AM.

[hav]

Wasn't there a study published not too long ago detailing how calorie restriction didn't increase the lifespans of some research orangutans? In respect to longevity, it's less risky for you not to adopt any kind of crazy diets. Might win, might lose.

There seems to be a couple of long-term studies on non-human primates with opposite results with regard to rhesus monkeys:

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study.

Caloric restriction delays disease onset and mortality in rhesus monkeys

The NIA study commented on their different results saying this:

Our finding contrasts with previous reports and suggests that study design, husbandry, and diet composition are important factors for the life-prolonging effect of CR in a long-lived NHP, similar to what has been shown in rodent studies

Not sure is that's an admission of a defect in their study or a claimed defect in the opposing study whose animals lived longer.

Howard

[scottknl]

Wasn't there a study published not too long ago detailing how calorie restriction didn't increase the lifespans of some research orangutans? In respect to longevity, it's less risky for you not to adopt any kind of crazy diets. Might win, might lose.

There seems to be a couple of long-term studies on non-human primates with opposite results with regard to rhesus monkeys:

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study.

Caloric restriction delays disease onset and mortality in rhesus monkeys

The NIA study commented on their different results saying this:

Our finding contrasts with previous reports and suggests that study design, husbandry, and diet composition are important factors for the life-prolonging effect of CR in a long-lived NHP, similar to what has been shown in rodent studies

Not sure is that's an admission of a defect in their study or a claimed defect in the opposing study whose animals lived longer.

Howard

The NIA study suffered chiefly because they included a bunch of monkeys from a military research institution that all died before 1/2 the age of the longest lived monkeys. This brought down the average to statistical insignificance. There were also many other problems with those studies, so I wouldn't put too much stock in their conclusions. The available human studies are better to use for judging health outcomes, but don't give mortality results.