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phenylalanine essentiality and role

essential amino acids phenylalanine tyrosine

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#1 caruga

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Posted 02 June 2015 - 06:28 PM


Does phenylalanine have any role outside of being a precursor to tyrosine?  If not then I wonder then why they don't say tyrosine is the essential nutrient rather than phenylalanine.



#2 abelard lindsay

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Posted 03 June 2015 - 05:43 AM

L-Phenylalanine is a direct precursor to Phenethylamine which is the body's natural TAAR1 receptor agonist.  It's broken down pretty quickly by MAO-B.  

 

From Wikipedia:

 

In a resting state, phenethylamine is synthesized in catecholamine neurons from l-phenylalanine by aromatic amino acid decarboxylase at approximately the same rate as dopamine is produced.[27] Because of the pharmacological relationship between phenethylamine and amphetamine, the original paper and both reviews suggest that phenethylamine plays a prominent role in mediating the mood-enhancing euphoric effects of a runner's high, as both phenethylamine and amphetamine are potent euphoriants.[2][25][26]

 

 


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