6 replies to this topic

[xks201]

It is my understanding that desmopressin is a synthetic analogue of vasopressin. I see various notes of increased short term memory attached to one of these two. Will someone please clarify which one of these has supposed cognitive benefits? Desmopressin is extremely long acting and potent from my understanding compared to even endogenous AVP and thereby can easily engender side effects at low doses (from my understanding). Any comments are welcome. 

[Duchykins]

Are you basing this off of studies conducted before or after desmopression nasal sprays were banned for killing people?  

[xks201]

Didn't realize they were banned. I was curious because the stuff as prescribed is very potent and in my mind not a nootropic and is dangerous. Its nothing I would recommend anyone touch at all.

Edited by xks201, 04 August 2015 - 11:55 PM.

[Duchykins]

The sprays were banned, but not tablets.  Yet a lot of the nootropic blogs and bullshit like that sometimes cite the older studies that used the nasal sprays (and claimed some cognitive benefit), so it's a toss-up unless the site is very specific about where its information came from.

But I agree with you that there is no particularly good reason to try this drug for this purpose when there are dozens and dozens of better alternatives.

Edited by Duchykins, 05 August 2015 - 02:14 AM.

[xks201]

I was just under the impression that for whatever reason the analogue desmopressin did not exhibit near the supposed positive effects of vasooressin or whatever other analogues possibly.

[xks201]

The sprays were banned, but not tablets.  Yet a lot of the nootropic blogs and bullshit like that sometimes cite the older studies that used the nasal sprays (and claimed some cognitive benefit), so it's a toss-up unless the site is very specific about where its information came from.

But I agree with you that there is no particularly good reason to try this drug for this purpose when there are dozens and dozens of better alternatives.

Let me know if you have more info to my next q. thanks. 

[Duchykins]

I was just under the impression that for whatever reason the analogue desmopressin did not exhibit near the supposed positive effects of vasooressin or whatever other analogues possibly.

 

 

It's not only possible, it's probable.  We see different effects with synthetics all the time, even if they do the one specific job they were made for.  Our synthetics are never perfect copies of the real thing and our bodies aren't wholly fooled by them.

 

I don't know much more about the vasopressin because I've never tried it.  Sorry.