4 replies to this topic

[us3yournam3]

These cause a lot of forgetfulness, my guess it that it's a negative impact on ACH, so is this possible?

[prunk]

No.

[us3yournam3]

A serious response someone please.

[Kinesis]

The SSRIs are not in general anticholinergic.  Paroxetine has only slight anticholinergic activity; fluoxetine, sertraline, escitalopram, virtually none.  By far and away their neurotransmitter effect is restricted to serotonin, hence the "selective" part of Selective Serotonin Reuptake Inhibitor.

 

So if they are causing forgetfulness, it is probably due to serotonin inhibition.  Deleting that, then, would be deleting their main design target. 

 

Although it is not an SSRI, bupropion too lacks strong anticholinergic activity.  Of the antidepressent drugs in mainstream use, only the tricyclics have particularly notable anticholinergic properties.

 

It is still possible, however, that piracetam may help with forgetfulness, since it may do so even in people not taking other drugs.

[us3yournam3]

I guess I'm constantly fickle and this kind of anxiety is causing me problems.